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1Medical Health Institute - Wellness ExpertsPart 1 of 3 - Dr. Suzanne Ferree: Clockwise Longevity with Peptides & ...85335.725:55I love everything you said is on point about your book. It's literally a practical manual. You have an issue, go to a specific page, and there's a solution. The book is designed for you to be able to go just to that chapter. So let's say you have a GI problem. You don't want to read about the cognitive stuff. So you go right to the GI chapter, and you can learn about what we do with peptides and GI in that chapter. Across all the chapters, it's going to say over and over again. Please make sure you're doing all the things you've got to be able to sleep. You've got to eat right. You have to have kind of an underlying baseline before you can go into using these peptides. Because many of them will not be effective if they're not being used in the right body. The way that we call it is you have to be able to qualify for peptides. I give you come to us and you call us be like, yeah, I want this peptide. No, he's like, why not? He's like, because you're not ready for it. That's just simple. Like we're talking about the roof of the house. You don't even have a foundation. Hi guys, welcome to another episode of Beyond Biohacking Brothers where we explore all things, optimization, biohacking, longevity, and beyond. And today, as usual, I'm joined by my brother Miguel and we have the pleasure and privilege of having Dr. Suzanne Fere. Dr. Suzanne Fere is a double board certified physician specializing in family medicine and anti-aging and regenerative medicine. She has earned advanced certifications in endocrinology and peptide therapy and is recognized as a leading expert in the peptide world. An award-winning educator, Dr. Fere has taught medical students and residents and has served on the faculty of Emery University as well as organizations such as A4M, IPS, ACAM, and SSRP, which we are also approved for writers off. She is also a veteran of the US Navy. Thank you so much for your contribution, Doc, where she served as a physician. In addition to her clinical work, Dr. Fere is an author, her book, Counter Clockwise, using peptides to renew, rejuvenate, and rediscover was released in March of 2024, and explores the use of peptides in anti-aging and regenerative medicine. So get ready for a deep dive into the exciting world of advanced peptides. And as her book's title suggests, this is a way to turning back the clock. So Dr. Fere, thank you so much for being here. It's a pleasure and an honor to have you. And I think we're going to have a lot of fun. Yeah, this is great. I have two interviewers. That'll be awesome. So first, as always, we always like to hear about your personal experience. What brought you to the world of peptides? What got you interested? What sent you down this rabbit hole? Because we've been there done that, right? So we know that this is a path that requires a lot of time and dedication and intention. So what led you down this path? So it came from two directions at the same time that merged into this peptide. I'm always looking for, I always have patients who don't get better with whatever I'm doing. So let's, you know, percentage of people just don't get better with the things that we typically do. So you treat them with herbs and diet and lifestyle changes and getting them to sleep and you do all the things. And eventually, there's a select number of patients who don't get better. So we put them on hormone replacement therapy. And wow, most of those patients get better. And then we put them on, you know, ebu or ozone therapy. And most of those patients get better. And so you're sort of always looking for what's the next thing. But then at the same time I had my own journey, I used to be a competitive runner and had injured my hip. It's a condition called Trendellan Burger. Some people call it Trendellan Burger. You decrease the use of your glutes and you start using the hamstring as the power muscle for running. I'm very muscle. Yeah, and it's not the way to run. So I didn't have a coach. I mean, I was young so I could do whatever I wanted at the time, but at this point in my life, which was around 40, 45, I started to be unable to do probably 40, started to be unable to do the running competitively because of this pain. So I was at a conference, one of the big major medical conferences. And at the conference, someone was talking about this wonderful peptide called MGF, Mechanical Growth Factor, which is a derivative of IGF1. You probably have heard of IGF1 in the body. It's one of the things that growth hormone becomes when it grows up. Yeah. I love that. And MGF is one of the specific strains of growth hormone when it grows up, that it's used when the body has an injury. And so I went to this, I saw on the, there was a breakout session on MGF. So I go to this breakout session and I was like, wow, what is this magic that you're talking about? I have no idea what you're talking about. So I say that, but then at the same time, we had a bodybuilder client years ago who they called him Doc in the gym because he was the guy that knew about the peptides. Now he didn't really understand the cellular health of how it worked in the cells, but he knew how it worked in the body. And he could say you need to do this. And this, he started teaching me, this is years before this MGF conference. It started teaching me about peptides. So I was like, I don't know, this sounds a little gross, I can see you're not sure if I'm on board. And then this, I went to this breakout session. Of course, doctors are way behind the bodybuilders. Unpeptides. And so at the same time on my own journey because of my injury, I had moved from competitive running into competitive powerlifting. So my own journey had moved from one to the other. And then looking still for a way to heal this injury. So I'm at this conference. I go, oh my gosh, this is amazing. Gotta get my, get this MGF. How do I get this? Where do I learn more? Always, always, where do I learn more? And so I went to a conference, another conference a weekend, little quick thing out in California, where I mean it was firehouse to the face, every single peptide that was available from the compounding pharmacy. And the really at the time was one of them are making these. Of course, I was concerned for using some of the available over the counter online kind of research peptides. I just didn't know what we were making. I wasn't sure what was coming out of them. And so for my own use, I was concerned about making, using something that wasn't from a compounding pharmacy. So I found a compounding pharmacy that made MGF and started using it. And of course, now we know that you would use MGF and you'd follow that with IGF1LR3, that sort of progression of things. But at the time, this was all a brand new so the physicians were concerned. The research that was available was mostly in an order of two management trials with small numbers of people. And so, and our experience with using them was also very, very limited and learning how to do this syringes and how to draw things up. I mean, it was all well, well, less back then. Of course, now we have multiple compounding pharmacies that do this and lots and lots of clinical experience using them. But at the time, that's really what I was doing. So that was really fun. And it was really fun to realize after that conference, you just come home and you're like, OK, you make a list as you're in the conference of all the people you want to treat with each one of the peptide. I'm going to put the PC1557 on these 10 patients and these. So it just became, I'm just going to try it. I'm just going to try it. I'm just going to try it. We'll see what happens. You call your friends that you met at the conference and you say, what are you doing? What are you seeing? What are you doing? What are you seeing? And we started to do ask minds together where we were going to use it. And it was a thing that was effective and productive for our patients. The original study doses were not what we actually ended up using. So especially for cognitive things. So it was a lot of fun. The last 10 years have been, 15 years have been a lot of fun learning how to do that. Well, Suzanne, first of all, I want to ask you where did this motivation ignite from? Because it sounds like this was like almost halfway through your life. You're like, whoa, let me start lifting weights. Because Carl's and I, I mean, we trained six days a week of not seven. People ask, how the hell do you do it? I'm like, well, do you brush your teeth every day? Of course I do. Do you shower every day? Of course I do. Do you eat every day? Of course I do. Well, then you exercise every day, right? It just becomes a part of who you are in your identity. So Kudos to you with the amount of discipline and motivation and drive and passion you've had for optimizing and improving performance. Have you ever wondered why back pain affects so many of us? It might just be in the way that we walk. And we've seen firsthand the impact of footwork on posture, stability, and overall performance. And that's why we're excited to introduce you, Palova Shoes. Our ancestors walked barefooted, allowing their toes to spread naturally. Modern shoes, however, constrict your toes, forcing your body to compensate negatively, leading to poor posture and chronic issues like back pain. Palova shoes are engineered for comfort and designed to enhance your balance and posture. Experience walking as nature intended. Go to our website and visit MHI recommends to get our discount code and learn more about Palova's technology. For now, stay healthy and God bless. That's an alright. And like it always happens, it's always a health condition. Like we find that pattern among so many different practitioners that that's how they break the cycle of their training bias. Like the way that they break that cycle is they have either an injury or a health scare or they gain 60 pounds and they're like, what the hell is going on? And they go down this path. So you share something in common with a lot of really amazing scientists and practitioners who have gone through this personal experience that had really has transformed their approach to medicine and healing. Yeah. Yeah. And the name to the game to us is, you know, we're on the performance side and not on the body building side but on the performance side because we do big wave surfing and we like jumping off helicopters and skiing and doing all this extreme stuff. So our bodies have to be dialed in to perform at an elite level. So it's how do I get, you know, your brain and body to function no matter if you're 30, 40 all the way to your 80s, like if you were in your 20s, as safe as possible, right? Without hurting also the other side, which is the longevity side because the expense of performance is longevity. So it's kind of that rubric tube challenge of finding the medium between lifespan and health, no, health span and life expectancy, right? Correct. And here you talk about six to seven days a week. That was a new concept for me when I started competitive training was thinking about even on your non-training days, like when I'm not, when I wasn't training powerlifting, I was still training. I might be walking. I might be doing Pilates. I might be doing a yoga class, but you're still training on your non-training days. I'm not that they have me on my non-training days, yeah. Well, I'll add something that I discovered two months ago and we'll keep moving because I just love that we share that. I didn't know you were that passionate about it. Now I've started working and we're really pounding our hands on the table in regards to neuro-mechanical therapy, whereas, you know, if you run for years, you're triggering, as you saw, you weren't properly firing certain muscles, so you're wiring your nervous system to have certain fibers that should be off and the ones that should be, that are off that should be on, recalibrate them. And in order to do that, you have to break down the myofascial trigger points and adhesions that we build up and retrain the nervous system, so you're more moldable and adaptable and resilient. So the body meets, you know, the performance halfway, strength without flexibility and, you know, suppleness. It's like the wingspan of a bird, it won't fly straight. Correct, yes. I had a bad injury of my left QL last year. I guess it was a year and a half ago, as I was approaching my last competition, and it's because I did not have the neuro-mechanical therapy or neuromuscular rewiring. And so in our practice, we use Pilates Plus Neural Therapy, but in your practice, you have something that's different from that, but yes, you, that's it. So it has to be so intentional about that, especially with heavy lifters. Yeah, daily, it has to be every morning I wake up after I ground, I get photo-biased, I start my day with stretching every single day. And then you have to use like devices like, you know, hard balls and rollers to break down those adhesions. Once they're gone, you work on them once a month if you start building them up, but it's a process to break these things down. And then you have your flexibility back. You are correct, yes sir. So let's move on to the second question. In your book, counterclockwise, which is right in front of you guys, and it's a must read, and I promise you, by the end of this interview, you will find yourself going online and purchasing this book. So in your book counterclockwise, you highlight peptides as powerful tools for renewal and rejuvenation. One inspire you to write this book. So it was sort of, are you completely familiar with the concept of a can? A can is where you set down almost an altar or a the end of a time period where you've learned and learned and learned and learned and you're grateful for the things that you have learned. And now I'm giving and sharing that information with other people to revisit, revisit, revisit. I wanted to be able to give that information to patients, but I also wanted to be able to give that information to providers, either who didn't know about peptides or who knew a little bit, but wanted a little bit more comprehensive. This is very approachable. There are stories, vignettes about my patients and things that I have come across with my own patients. There's also a lot of science in there. So as much as I could pack in, there was a good bit of science. I know a lot of my patients really like knowing the information where things come from and they'll go look up all that information. But you can skip right over all that if that's not your goal and you can just look at the story and then the peptide stacks is the end of each chapter. The book is designed for you to be able to go just to that chapter. So let's say you have a GI problem. You don't want to read about the cognitive stuff. So you go right to the GI chapter and you can learn about what we do with peptides and GI in that chapter. Across all the chapters, it's going to say over and over again. Please make sure you're doing all the things you've got to be able to sleep. You've got to eat right. You have to have kind of an underlying baseline before you can go into using these peptides because many of them will not be effective if they're not being used in the right body. Oh man, I love that. No, I want you to say what are you going to say? But I love everything you said is on point about your book. It's literally a practical manual. You have an issue, go to a specific page and there's a solution. Don't go online and read George from, I don't know where, talking about peptides and some bogus Mickey Mouse protocols. Here's legitimate, scientific evidence base and basically, you know, over viewed by a profession like yourself. And I love what you mentioned that it's congruent, right? Like you can't, you have to know what body you're putting these peptides into. Like if you're super inflamed and you know there's a friend of ours that calls metabolic dumpster fire. Like, I mean, how effective do you think these peptides are going to be? So there is a lifestyle that you have to maintain in order, the way that we call it is you have to be able to qualify for peptides. Like if you come to us and you call us be like, yeah, I want this peptide. No, he's like, why not? He's like, because you're not ready for it. That's just simple. Like we're talking about, you're talking about the roof of the house, you don't even have a foundation. So let's talk about the foundation first. So that will lead me to the next question because, you know, we do have an order in syntax and I think you do too. I think you see that in terms of how biochemistry works, which is really refreshing to hear. So in your view, how do peptides compare to traditional treatments like bioidentical hormones, which you mentioned, in terms of their efficacy and safety, especially concerning performance, age-related decline and chronic disease? So it depends on where you're coming to me in the process, right? If you're coming to me as a 20-year-old, I'm certainly going to look at your testosterone with a 20-year-old man and you're doing some sort of, you know, going to the top of some kind of building or mountain or going to a mountain or something like that. Or Boston Marathon. I'm going to certainly check your testosterone because there are reasons why you may have a low testosterone. Even at age 20, there's lots of endocrine disruptors that we're involved in every day. And so I'm going to look at those things. I'm also going to look at what your estrogen is at whatever age you are because I want to make sure that you're not overproducing or taking all of your testosterone converting into estrogen. Again, there's lots of reasons why that may be happening, even in a young and fit male. Consuming plastic. When people eat those plastic meals that we see it all the time, their estrogen is out of the roof. You got it. Exactly. Things like using the spandex clothing that we're all wearing. I mean, the PFOAs are really toxic and they can really affect a lot of the things in our bodies. Yeah, the Poggy, or whatever. That's what, 2024, they tested, I don't know how many people, they tested, but every single male testicle sack was found to have microplastic in it because of the polyesters. Yeah. And then you know what? And I'm sorry to kind of interrupt like your flow. It's just this is really important because there's not a lot of practitioner. So it's really refreshing to hear you say this because this is kind of like our foundation. Because a lot of people will say, why? Why am I 20? I have the testosterone levels of an 80 year old. Like that's the big question, right? And it becomes deeply psychological. And it's like, hey, listen, it's not something you did or failed to do. The fact of the matter is that we are now consuming a credit card's worth of plastic a week eating and drinking them like ourselves were not designed to metabolize plastic. Yeah. You know, this is a reality. And this is just one factor, right? There's many other factors. So it's really refreshing for you to say that because that, you know, we have to check and we have to educate people that these things in our environment are deeply crushing our health. And this is why we even need all the stuff that we're talking about. Yeah, and who's that? In those patients, that would be a patient I would probably start them out with Ebu F, which is one of the available Ebu machines that's there because we know it's a white paper granted. It's not a peer reviewed article, but in a really substantial white paper, Angie Valdevesco was able to prove that the Ebu F is able to pull microplastics out of the blood. So it's definitely worth moving in that direction. So guys, and gals, for those that you know, what Ebu is, it stands for extra corp, how do you say extra corporeal blood ozone oxygenation? Basically, they filter out your blood through a system where you're hooked onto two arms. They filter out all the garbage in the breath that builds up in your blood. Some of it is microplastics and eds, and then they refilter it after they pass it through a spectrum of light where they enrich the blood with light and put it back into your body. When it comes out as like a red wine, when it comes back into your body, it's like a Ferrari red. So yeah, and just to kind of close that circle, go ahead. And I love, again, as he said, I want to echo on the fact that you're talking about EDC's and plastic because our biggest thing is nutrient deficiencies, the toxic burden from environmental toxins and the aging process. And we interviewed Dr. Shana Swan, who is a PhD, has a PhD, Harvard grad, and has a PhD in reproductive and environmental epidemiology. And she has shown the current data she showed is that in the last 57 years, men all over the planet have lost 59% of their sperm count. And sperm count into testosterone on different branches of the same tree, which are still interconnected. So we're seeing that 16, 18 year old boys with a testosterone, not even of an 80 year old, I got 200 with a free tea of two. It's so they never get to experience their masculinity. And this is why I feel it's so important to basically pounce on this because now we just got back, what was the conference we went to? Changing life destiny. Changing life destiny, we found a company that looks for microplastic particles that we accumulate. It's the first company of its kind that we can identify not just like Thalate, Oxybenzone, BPA and all these chemicals, but actually the amount of particles that we're carrying and they developed a novel supplement called chemo. It's kind of like a probiotic that feeds on the plastic. Yeah, it feeds the plastic and then two months later you can measure and you can be back to baseline because if you have microplastic in your body that's in parent-year reproductive system. We're still trying to have children, right? So our reproductive system has to be intact and I think that this is something we can share off camera with you out of the company. But I think every physician should be testing for microplastics in today's world. And just to close that circle on it, doc, and now continue. I'll let you finish on the HRT. It's super-percent, but I think this is really valuable for people because the fact of the matter is that from an evolutionary perspective this is brand new to ourselves. 90% of these chemicals weren't even around 30 years ago. This is the fact. And just one plastic water bottle, this is what we learned from this company. This is really important for everybody to listen. Just one plastic water bottle can contain over 240,000 plastic particles that you are ingesting. And this is what our cells has to process, right? So continue with the HRT. Sorry for seizing your thunder. I mean, in that study, even to mention the things that are blocking our hormone receptors like fluorine, like fluoride that's blocked. You know, there's so many things that are blocked. So all of that involved, we just have to start with what are the things we need to be doing for our bodies? What are the things we need to be getting rid of in our environments that are contributing to the problem? And then making sure that we're nutrient optimized. It's so easy for us in our general daily lives to not be including all of the nutrients that we need to include. So that's sort of baseline. And then moving the body, I'm a huge proponent because moving from running to powerlifting and now moving into bodybuilding, this is, I think resistance training is so critical as you age, as you go past 40 years old, resistance training. You know, my dear friend, Carl, with a muscle is the currency of aging that is, that I'm such a huge fan of that phrase. And I think it's really, really true. The more I read, the more I believe it's true. Yeah, absolutely. So I think all of those are critical pieces that we need to be aware of. And especially when we think about all the beautiful chemicals that are released, when we do resistance training from our exercising muscle that contributes to anti-aging. So not just because we're not gonna fall, but also because of what, chemically, biochemically at the cellular level is happening to us and as a result of resistance exercise. So that's what I would say is super important for us to do. And look, I'm responsible for cutting your flow. So, but if I hear where you were going so we can wrap the question up, is that, I mean, you would focus on HRT first if someone is hormonal lead-in-fishing, but if someone is not necessarily hormonal lead-in-fishing, this is where you would actually open the door for peptides. Correct. Exactly. Yeah. Yes. So then I'm gonna say, okay, you're optimized. Okay, you have all of your things in place. You're looking really great. I'm super excited about this. Let's add on some things that are gonna help with energy, repair and recovery and body composition. Inflammation detoxification, I mean, it's endless. It's endless. That's awesome. And by the way, we like to call it for men to Soshram Dificiency Syndrome. I mean, testosterone-resistant syndrome or for women, hormone-resistant syndrome, when they're exposed to these EDCs and all their levels are dialed in, but they're like, Doc, I don't feel any different. That's because of the remodulation of the receptor where you have a seno-ashigen blocking it and the real bio-identic hormone can actually activate, you know, the receptor to actually express itself. And sometimes it's as simple as something like iodine. Yeah. It's simple, simple. You know, get tested because you can have excess iodine, but sometimes it's really, really a simple change for my patients that can make a huge difference in their, in their ability to receive that hormone. Yeah.