Would love to know what the conversations are with Big Pharma at the moment? ?
negative
33
u/Chemical_Sky6013
Thank you u/MGK_2 once again for an excellent post. I've written in the past about my long journey with CYDY, and many of you have shared similar experiences. It's been really hard to stay invested for all these years and not lose hope.
What I didn't share earlier, was that around the time that this thing hit 14 cents in November 2024, I saw a post on FB that said,
"Sometimes when you're in a dark place, you think you've been buried, but you've actually been planted."
And that's when I told myself it was time to start buying again.
And now those seeds are about to bloom for all of us!
This company is almost entirely owned by individuals... who kept the faith when everyone "in the know" fled. And soon we will have a beautiful garden to enjoy. Congratulations to all the longs!
positive
33
u/Cytosphere
This is an excellent explanation of complex phenomena.
positive
28
u/Tra-Kal34
Praise the Lord, we are getting closer and closer.
positive
27
u/paistecymbalsrock
The data has arrived!
positive
24
u/upCYDY
Wahoooooo ‼️ thank you MGK for this thorough explanation‼️🧨🙌🙌🙌 THIS🤗👍‼️FANTASTIC NEWS 💃
positive
23
u/surfgolf4life
Great post MGK. Patiently waiting for PRs and more good news👏👏👏
positive
23
u/Jtzdad5673
A couple of years ago my niece told me about a friend, a close friend; who was intelligent and kind. He had everything it took to lead a very successful life, until he was diagnosed with GBM. He faced his illness with great courage and grit. He truly lived “one day at a time” knowing he didn’t have much time left. When my niece told me about his illness, I immediately told her about CytoDyn and leronlimab. I continued to stress the importance of having his physicians use the “Right To Try” statute and get him on leronlimab. Of course his physicians never heard of CytoDyn or leronlimab, nothing came of it, and once again the GBM won. I think he lived about 18 months after his diagnosis. He wasn’t even 30 years old when he died. The same thing happened when my cousin with a wife and four children had a massive stroke a few years ago. (I’ve posted about this here before). I called CytoDyn myself to request leronlimab for my cousin and Dr Scott Kelly was more than willing to send it to his physicians in Houston, but they (his doctors) refused to contact CytoDyn. He died six months later, on his 50th birthday. Had their doctors followed through, both the young man and my cousin might be alive today. Go CYDY!
negative
22
u/Pharma_Junkee
Excellent breakdown MGK
positive
21
u/Missy2021
Just a matter of time now, that Leronlimab blows the doors off of Big Pharma! Thanks again.
positive
20
u/Pharma_Junkee
🙏🙏🙏
positive
19
u/Upwithstock
BOOOOOM! Thank you for the plain language breakdown my brother! Your post was by far the best read I have had regarding the science! Loved: The abstract is a declaration of Kinetic Validation! The physics of the TME has been solved!! Now let the interested BP’s come to PAPA Dr. J and Uncle Hoffman! The Golden Tsunami is coming!!
positive
18
u/Pristine_Hunter_9506
Thanks brother another step forward.
positive
17
u/megadunamis
Thank you for your analysis of the results. GBM is a tough cancer to crack, call Leronlimab to the rescue...
positive
15
u/twinter11
That was nice write up!
And it look like pestell and team were hard at it and I'm sure more to learn.
I can't think of anything to ask
Thanks Mgk!
positive
15
u/Doctor-MTJ
MGK, This IMHO is one of your very best posts. Great explanations of very complex processes in a very concise, easy to understand manor...Thank you my friend for all that you do! Things are really coelescing at a very fast rate right now. It feels like this is all leading to a big Crescendo very soon!
positive
15
u/waxonwaxoff2920
Many thanks for the work you do here MGK. YOU ARE APPRECIATED BROTHER. 🫡
15
u/No_Mathematician299
I don't have anything to add to the discussion other than thank you.
Thank you, MGK_2, for helping us make sense of everything.
Thank you, Cytodyn's team. They are a bunch of diamond cutters, working tirelessly.
I even thank myself for holding on during the bad times.
positive
13
u/Lopsided_Roof_6640
Thanks MGK for the breakdown. Let us see what the new FDA does with this data. CRC, TNBC, and now GBM would meet any definition of unmet needs. Hard to ignore a hat trick. Notice that Pancreatic cancer has popped up here and there in Cytodyn literature. Would not be surprised if it gets a mention in the next update.
11
u/AggieEC3
After reading through the original post and many of the responses there’s a lot to unpack here, but stepping back, what stands out most is how the conversation is evolving from what could happen to how this might actually work in practice.
The breakdown around glioma stem cells and OCR is especially compelling. If recurrence is truly being driven by those “seeds,” and this approach is impacting the metabolic engine that keeps them alive, that’s not just incremental, that’s getting closer to the root of the problem. The idea of starving out the cells responsible for regrowth, rather than just cutting down the visible tumor, is a meaningful shift in how this disease is approached.
Where it really starts to connect is on the combination side. GBM has been the place where a lot of otherwise successful therapies go to stall out. If the issue has been access, both physical and immunological, and that barrier can be altered, then it makes sense why pairing becomes the focus rather than replacement. “Prime and pair” isn’t just a strategy, it’s a different lens.
The OCR data, the dose dependency, and the early signals around reduced spread all point in the same direction, but like anything in this space, it still has to translate clinically. That’s the next step that matters. If it does, then the implications go well beyond a single indication.
Appreciate the way this was laid out, it helps connect a lot of dots that don’t usually get tied together in one place.
And to build on the analogy… if checkpoint inhibitors are a high performance engine, and this approach is about finally giving them traction, then maybe another way to look at it is this…
right now, the system looks like a luxury car with a manual transmission, but no clutch. All the power is there, all the engineering is there but without that missing piece, nothing engages the way it’s supposed to.
If this data holds, we may finally be looking at what allows the gears to actually connect.
Thank you MGK_2 for continuing to bring clarity, put in the time, and connect the data in a way that moves the conversation forward.
11
u/Cytomight
This is turning out to be a BIG DEAL‼️😁😆
positive
10
u/Practical-Archer-124
[deleted]
neutral
8
u/jsinvest09
As I was reading that I could literally hear the excitement in your voice MGK.. are time is here. Are time is now?So, enjoy everyone, because here it comes...
7
u/jsinvest09
Good morning
6
u/sunraydoc
Thanks, MGK, you are the rock. That OCR reduction in the hypoxic tumor center really stood out for me, Yet another previously undiscovered MOA.