Channel: TED-Ed clear
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1TED-EdWhat are stem cells? - Craig A. Kohn22323592727384260.3positive4:11Imagine two people are listening to music. What are the odds that they are listening to the exact same playlist? Probably pretty low. After all, everyone has very different tastes in music. Now, what are the odds that your body will need the exact same medical care and treatment as another person's body? Even lower. As we go through our lives, each of us will have very different needs for our own health care. Scientists and doctors are constantly researching ways to make medicine more personalized. One way they are doing this is by researching stem cells. Stem cells are cells that are undifferentiated, meaning they do not have a specific job or function. While skin cells protect your body, muscle cells contract and nerve cells send signals, stem cells do not have any specific structures or functions. Stem cells do have the potential to become all other kinds of cells in your body. Your body uses stem cells to replace worn-out cells when they die. For example, you completely replace the lining of your intestines every four days. Stem cells beneath the lining of your intestines replace these cells as they wear out. It's hope that stem cells can be used to create a very special kind of personalized medicine in which we could replace your own body parts with, well, your own body parts. Stem cell researchers are working hard to find ways in which to use stem cells to create new tissue to replace the parts of organs that are damaged by injury or disease. Using stem cells to replace damaged bodily tissue is called regenerative medicine. For example, scientists currently use stem cells to treat patients with blood diseases such as leukemia. Leukemia is a form of cancer that affects your bone marrow. Bone marrow is the spongy tissue inside your bones where your blood cells are created. In leukemia, some of the cells inside your bone marrow grow uncontrollably, crowding out the healthy stem cells that form your blood cells. Some leukemia patients can receive a stem cell transplant. These new stem cells will create the blood cells needed by the patient's body. There are actually multiple kinds of stem cells that scientists can use for medical treatments and research. Adult stem cells or tissue specific stem cells are found in small numbers in most of your body's tissues. Tissue specific stem cells replace the existing cells in your organs as they wear out and die. Breonic stem cells are created from leftover embryos that are willingly donated by patients from fertility clinics. Unlike tissue specific stem cells, embryonic stem cells are pleuripotent. This means that they can be grown into any kind of tissue in the body. A third kind of stem cells is called induced pleuripotent stem cells. These are regular skin, fat, liver, or other cells that scientists have changed to behave like embryonic stem cells. Like embryonic stem cells, they too can become any kind of cell in the body. While scientists and doctors hope to use all of these kinds of stem cells to create new tissue to heal your body, they can also use stem cells to help understand how the body works. Scientists can watch stem cells develop into tissue to understand the mechanisms that the body uses to create new tissue in a controlled and regulated way. Scientists hope that with more research, they can not only develop specialized medicine that is specific to your body, but also better understand how your body functions, both when it's healthy and when it's not.
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@@SaveTheCordFoundatioLove the graphics and the explanation is very clear...but....and this is a big but here... you skipped completely over the fact that you can collect non-controversial stem cells from cord blood at birth without causing harm to the mother or child. You mention embryonic but this is a far more controversial source of stem cells. Why not just use something that we would otherwise throw away? Let's use the cord blood collected just after the birth of a child. Give life twice. Save the cord. ?negative698
@@MilanMilan0000ok, so stem cells don&#39;t do much in their original form, but they can transform into other types of cells...<br><br>are stem cells dittos? ?neutral649
@@rydonwunaliI want to learn how to animate like that one day.positive507
@@magicstix0rThe liver was a pretty poor choice for an example on regenerative medicine... It regenerates itself already...negative448
@@Derek-d5097Okay, I have one question? WHY ARE WE NOT FUNDING THIS? ?negative346
@@meesdegroot1896if you read this, i hope you will become succesfulpositive158
@@raiden5867Does this mean we can bring Harambe back? ?negative146
@@zwolfelfenIn fullmetal alchemist philosopher&#39;s stones are made from humans, so are stem cells basically philosopher&#39;s stones because they increase life expectancy and are made from embryos which are pretty much babies but unborn.negative120
@@GriffenDesigns<a href="https://www.youtube.com/watch?v=evH0I7Coc54&amp;t=203">3:23</a> Don&#39;t think I didn&#39;t notice Doctors House and Farnsworth, you sneaky animators you! ?positive114
@@ElementalSkater0013D Printing + Stem Cells =  no more waiting linespositive83
@@CrazyFactory741The eevee of cellspositive70
@@craigkohnHello all! A couple quick responses to some valid questions: -Currently most stem cell therapies are based on tissue-specific (or &quot;adult&quot;) stem cells. The treatments are very limited in what they can do (hence the interest in other kinds of cells). -Tissue made from embryonic pluripotent stem cells does face the risk of rejection by your body. This is why there is so much interest in induced pluripotent cells, which would come from your body but have the capabilities of embryonic stem cells. neutral62
@@thomasmckonigal4191Embryonic stem cells aren&#39;t necessarily aborted babies with regards to IVF. If a couple are not able to have a baby they can obtain the necessary requirements for life from donors. The sperms and eggs are brought together in a lab where they form embryos, but say for example 5 embryos were made but the doctor only implants 2 into a surrogate (or the mother) and the doctor freezes the other 3. She falls pregant and gives birth. Now maybe the mother wants more children then she can use the remaining 3 embryos to be implanted in her and can fall pregnant. BUT the mother may not want to have any more children hence she is given the option to maybe donate the embryos to another couple who wish to have a baby but can&#39;t OR donate them to science - in this case stem cell research. This is the reason why stem cells is such a controversial topic because the remaining embryos are more or less unborn babies and it may go against the grain of several religions.neutral46
@@benjohnson4925As a wise man once said, “why aren’t we funding this?!” ?positive23
@@missstudy1226<a href="https://www.youtube.com/watch?v=evH0I7Coc54&amp;t=135">2:15</a> To add to that:<br>For Leukemia, the curative effect of stem cell transplants is actually due to the GvL effect, or Graft versus Leukemia effect. In other words, it&#39;s an IMMUNE-based response where the new cells you received (LTCD8, NK cells) are literally directed against your cancerous cells, thus curing you of Leukemia.<br><br>(or at least that&#39;s me summarizing what I understood from today&#39;s lesson. I really like your video btw) ?neutral22
@@patrickmilton9168+TED-Ed That was DEFIANTLY Professor Farnsworth from futurama at <a href="https://www.youtube.com/watch?v=evH0I7Coc54&amp;t=205">3:25</a> ?positive17
@@uimasterskill&quot;Why two legs? Why not three?&quot; Lol. ?positive15
@@xiiaocbzaii1996Thank you for the clean and simple explanation about stem cells !!!!positive15
@@franzsno70193.31:weird blob found in my head ,gonna call it brain after my son<br>negative15
@@HanaChowdhuryI dont get itnegative14
@@pokegi1022The part when it says pluripotent stem cells can rise all cells. The correct type is to totipotent.neutral10
@@haydencook682I just wish the best cells weren&#39;t from unborn humans. Idc what you say, as soon as the egg is fertilized, there&#39;s potential for human life (no way to refute that)...at that point to me, it&#39;s up to nature on whether it makes it or not.negative10
@@supersmashmaster43This vid helped me alot with my report :) positive9
@@urgandmaI can&#39;t wait for this shit. Joint injuries will now actually be <b>healed</b> and not <b>temporarily better til you get old and it really craps out on you</b> negative9
@@allanallan2941So basically, as long as you&#39;re living, stem cells can cure anything, just cut and replace. But what would happen if a brain was made from stem cells, and then transplanted? Would it be the same, or would it start from square one again? ?neutral8
@@austinmarshall8892Who here is from school? 😂😂 ?neutral8
@@crazydudetzI love how they always incorporate media icons into their videos.<br><br>House and Futuramapositive7
@@AnnaidatrolleThis was so helpful, thank you! I liked that he did not speak fast, because English is not my mother tongue, so it&#39;s nice when you find these videos that explain everything in a nice waypositive7
@@nukeman0199<a href="https://www.youtube.com/watch?v=evH0I7Coc54&amp;t=202">3:22</a> Gotta love that House XD ?positive7
@@IsieePersonaU know TED? If I had seen this in 2007? i wouldve just gone straight to premed after highschool at 17<br><br>Man.... I never realized biology and medicine can be so fascinating.<br><br>Thank you for always sharing information like this to the world. <br><br>I had traumatic Brain injury in 2018 and this video answered so many hows and whys why I got the slim 1% rate of full recovery as one of my nueuro surgeons told me.... <br><br>Thank you for making me understand so many hows and whys<br><br>Happy new Year ?positive6
@@benabelePoor unborn babies. So sad.negative6
@@B3bita1215Hooray for stem cells!!positive5
@@TheDemolitius<a href="https://www.youtube.com/watch?v=evH0I7Coc54&amp;t=201">3:21</a><br>Farnsworth + House = God<br>:P ?positive5
@@reshmaparekh6310Wow, just look at those amazing animations!positive4
@@sanojsanoj5943informative and easy to understand. good job sir!positive4
@@huijinan5036Thank you so much Ted-Ed! This video is what I need! I have a summative assessment on Friday!positive4
@@fenipatel7937Love how you guys explain these things... makes much more sense.positive4
@@luckyHorseshoePony12This. Reminds me of a sad South Park episode kenny dies and the stem cells can grow muscle tissue sorta and kenny died and cart man used the stem cell to make a pizza placenegative4
@@rigelaltair465The most accurate explanation about stem cell. Love.positive4
@@ZerepzerreitugIt&#39;s great that I was just wondering about stem cells when I found this video. I wonder. Do the embryonic stem cells work for any person? For what I understood, if they&#39;re donated, then their DNA is different than the patient they&#39;ll be implanted in, doesn&#39;t that causes a problem? It says that these cells are donated by fertility clinics. I&#39;m not sure how this will sound, but maybe this is a way to un-demonize abortion procedures? By retrieving stem cells from the embryo to help others? ?neutral4
@@jasroop_sandhuGreat Clip!<br>Really explained the process well.positive3
@@michaelabulman8451Thank you Ted ed...you teach me when my bio teacher doesn&#39;t 😄😂positive3
@@rainyraelyn9649love this video. its very accurate and informative!positive3
@@Aven333The real question is would you rather listen to playlist 1 or 2 at <a href="https://www.youtube.com/watch?v=evH0I7Coc54&amp;t=13">0:13</a>. (playlist 1 is the only right answer) ?negative3
@@khaziayintime to get more brain cellspositive3
@@nadatazouti2218I am here from online lesson...say hello to my science teacherrrrr😘🖕(😭😭😭😭😭)negative3
@@Roy-G-BivI had a stem cell transplant.....science is awesomepositive3
@@Atlas_Travis<a href="https://www.youtube.com/watch?v=evH0I7Coc54&amp;t=202">3:22</a> lol the scientist dude kind of looks like the dude from Futurama ?positive3
@@woodfur00Fat, skin, muscle, and nerve cells look a lot like air, earth, fire, and water. Is that intentional? ?neutral3
@@reginaldpooftah4525wow! this is awesome. stem cell can actually be used to alter your body parts. so tommorow really rich parents can go to  doctors and alter the kid. for example, if they say i want my kid to win a noble prize in physics, the neuron branching can be made thickernegative3