Exosomes won't do much for texture, they only help with the health of the skin and hence will help with hyperpigmentation a bit. For texture, you'd need to try microneedling, or chemical peels, or fraxel.
I've tried both exosomes and PDRN meso therapy, and definitely prefer PDRN. I have done Rejuran Healer meso a few times and it has made my skin 1-1.5 shades lighter and overall clearer (in reality it brought back my original shade as my face was so much darker due to constant scarring and inflammation). It also gives a bit of a plumping effect because of collagen building which is good for pores and texture very slightly. But the most surprising effect was that it (almost) completely stopped my deep cystic acne. I've had acne all my life (I'm 37) and Rejuran finally strengthened my skin barrier to stop clogging and having acne all the time. Now even if I get one here and there, it comes and goes quickly without causing a lot of damage and hyperpigmentation.
I read on another subreddit that you need to have collagen building meso therapy 3 times in a row every 4-6 weeks (building time for collagen) and then you won't need to have it for a year as it builds upon itself if done at the right intervals. Otherwise single sessions will feel good for a while and then the skin resets. The effect of reducing acne was immediate for me after the first time, but they came back after I took a break. And now I'm on course to get the 3rd in a series, but I don't know if the effect will last a whole year, or it's just a marketing gimmick. We'll see. I'm also thinking of trying Juvelook meso, as they say it helps with hydration and achieving that glass skin look.
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u/Skinsymphony
From what I’ve seen, exosomes seem promising but still kind of early in terms of solid evidence, especially compared to more established treatments. A lot of the results people talk about seem to come from in-clinic use alongside things like microneedling, not really at-home products. Personally I’d be cautious about the hype vs cost and stick with proven treatments unless you’re getting it done professionally.
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3
u/Skinsymphony
From what I’ve seen, exosomes seem promising but still kind of early in terms of solid evidence, especially compared to more established treatments. A lot of the results people talk about seem to come from in-clinic use alongside things like microneedling, not really at-home products. Personally, I’d be cautious about the hype vs cost and stick with proven treatments unless you’re getting it done professionally.
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u/kstations
The at-home exosome products are a bit of a different category from what's used clinically. Real exosome preparations need cold-chain handling and lose bioactivity pretty quickly outside of that, so what's in most retail formulas is probably closer to lipid vesicles being marketed under the same name. For the texture piece especially, the mechanism that actually moves the needle exists in the clinic, not in a bottle.