Reprogramming T cells does seem very promising.
Using PSMA to guide radiation to cancer cells is also very promising. We need to get it approved for salvage.
My uro believes a lot of men today will avoid metastatic cancer with one or more of these.
positive
3
u/Practical_Orchid_606
There is a phrase in law that goes like this: "Asked and answered." It means that a lawyer can only ask a question once during deposition or oral examination. Using the immune system to fight cancer has already been tried with Provenge with only lukewarm success. Do not be fooled by Dr. Marson's enthusiasm for his project. He is an academic and will be judged by the quality of his research even if it results in a Provenge quality treatment. Academics need to 'sell' their projects for the purpose of attaining money to continue his research.
Mother nature has blessed PCa men with several biological gifts. First, unlike other cancers, PCa is slow growing. It has a built-in warning system with the PSA protein that can be measured. Men have a built-in mechanism to halt PCa growth by lowering testosterone. And finally, PCa cells express a protein called PSMA.
I agree with Special-Steel in highlighting PSMA guided radiation as an area where new therapies will be developed. This technology is now available as Pluvicto which is for late stage advanced cancer that is castrate resistant. I believe in 3-5 years, it will be available at the initial recurrence level. Nowadays, the treatment intensity at the Gleason 7-10 is high due to fear of BCRs. If this fear is diminished due to robust PSMA guided radiation, all men with PCa will benefit.