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Need help understanding exosomes/growth factors/peptides/pdrn

pferdchenpojuzt

58.2

positive

2026-03-27

commenter	comment	sentiment	upvotes
u/drifter91	They can be quite game changing, but a lot of those ingredients require a channel to penetrate through like microneedling or injections. A lot of products proclaiming to have them such as pdrn creams and serums are usually not very effective because of lack of penetration capability and low molecular weight.	neutral	7
u/Mlle-Aqua	I use pubmed to search for literature reviews that explains clinical trials that have investigated the application of these ingredients in cosmetic or medical applications. Literature reviews are useful because they can provide an overview of what the research says about these ingredients. Make sure to make your search a bit specific. I usually add the ingredient and the application that I’m looking (ex: PDRN and cosmetic applications or wound healing) because these ingredients have been used for things outside of cosmetic research and you want to narrow down your search to the relevant applications.	neutral	3
u/New-Can-432	Curious to see responses to this. I used Calecim Professional Serum after laser and did heal well (tho it was my first laser so can’t compare) and I have been using it when I have a blemish and it seems to help speed up healing and avoid PIE. I just bought Allies of Skin Growth Factor 2-3 weeks ago. Too soon to say what impact it’s having.	positive	2