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1r/HotScienceNewsCompulsive behavior is caused by brain inflammation - not bad habitssoulpost23520%14082.5stem cell therapy2026-03-09
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u/fhwoompableCooperHuge news tbhneutral125
u/babyhuffingtonThis makes sense based on common symptoms seen with people who have experienced a traumatic brain injury like myself. I’ve noticed that I can go through phases where I keep repeating the same thoughts in my head and I’ve noticed that it’s tied to when I’m sick. This makes it hard to seek out therapy because when I tell a therapist about it, they completely dismiss it. I have to keep it all to myself because no one understands.neutral99
u/Fuzzy-Albatross-9206So how do we decrease inflammationneutral95
u/thebigyin3This does correspond with what is seen clinically but as always need to be careful in attributing causation.neutral48
u/Ok-Rule9973The scientific article doesn't state that people with OCD have heightened inflammation, but that inflammation can cause OCD-like behaviors... In rats, and in controlled situations. It's a very big leap to say that OCD is caused by inflammation. We know that human behaviour is extremely complex, it should not be reduced to a single factor like that except when the science actually back this. And I'm not sure about whom said that compulsive behaviors where a sign of loss of control. I've always read that it was overcontrol.neutral20
u/neatyouth44YES! And it can be ironically made worse if encountering “focus on what you can control” language in therapy right off the bat. Same with eating disorders. We need to be careful about “calming” people into pacification of damaging and abusive environments, though. And that is very hard to seperate from systemic misogyny or patriarchy (harming both men and women, to be clear).neutral12
u/Otherwise_Cry95A lot of cases are caused by past strep infection and the resulting inflammation effecting the brain’s basal ganglia.neutral4
u/Bababooey0326Glad this is finally being discussed and recognized by medical powers that be Diet/gut you are what you eat. The improvements you will find within yourself once what you put in your body is under control? It's miraculous.  Inflammation is key to so many issuespositive4
u/InteractionGreedy249The brain inflamed will mainly go insane.neutral3
u/skyfishgoocooler heads truly do prevail perhaps the answer is as simple a taking beat to let the swelling go down before you make any life changing decisions. this sounds like ancient wisdom even tho they probably had no idea about the actual mechanics involved.neutral3
u/Mountain_Elk_7262So how do we increase inflammation enough to motivate but keep it under enough control to mitigate the potential down sides? ?neutral3
u/Ardent_ScholarMy word. This must be why glp-1s lessens obsessions with food, caffeine, booze, gambling, etc.neutral3
u/GravyMealTeam6I wonder if this is another reason why GLP1 drugs help addictions. Not just cause of the dopamine aspect but also they are anti inflammatorypositive3
u/Dedicated2bMedicatedSo how do us with ADHD increase inflammationneutral3
u/secondrunnerupIs this why GLP-1s are having an effect on people’s smoking and drinking habits? From what I understand they are anti-inflammatory. ?neutral2
u/Forward_Motion17How many times do I have to say psychiatry and psychology need to move in to a “whole-body” model before it’s taken seriously smh2
u/Overlord7193Seems promising but still needs work based on my lived experience with ocd.2
u/TemporaryElk5202Sweet jesus I swear I have felt so crazy explaining to doctors and autoimmune neurologists that my OCD gets better with anti-inflammatories, and gets worse alongside my autoimmune disorders.2
u/AttorneyUpstairs4457I knew this to be true for years! I have very pronounced compulsions to research health solutions to my problems when I’m experiencing brainfog (neuro inflammation). Think doom scrolling down rabbit holes instead of sleeping m or cooking/cleaning. I’ve finally discovered that my inflammation is caused by SIBO which I’m trying to treat.2
u/[deleted]For years, the scientific consensus was that compulsive behaviors like repeated handwashing or gambling were simply "autopilot" habits that overrode a person's self-control. As someone who's lived with OCD for several years as well as a couple other disorders that are even more misunderstood.. The shit scientists believe just really baffles me sometimes. You can just ask us, it's very clearly not an autopilot thing. It's the complete opposite, you are incredibly aware to the point that it's intensely uncomfortable and completely overwhelming How on earth did they ever think it was an autopilot behaviour?! Did they even bother to ask people who have OCD what its like? 😂2
u/peterjohnvernon936Often enough there is a reason for bad behavior other than the person being evil.2
u/baaaananaaaI have intrusive thoughts and take things like ashgawandha and NAC, glycine etc to ‘calm’ my head. I don’t think inflammation is the reason for intrusive thoughts but likely can make it worse. When I gave birth, my hormones made my intrusive thoughts unbearable. It was literally like torturing myself with thoughts about things going wrong, that were completely unrealistic.1
u/SGT_KPYea, BUT if I don't continue my behaviors and habits, then I may become a bad person. But then again, I would be a bad person if I didn't try to better myself. So, I'll try to better myself. But if I better myself then I won't be doing my habits, and then I'll be a bad person...1
u/TheShimmeringCircusSo anxiety/OCD based behaviors stem from trying to control and seek out less scary outcomes? Shocked… I’m shocked, I tell you.1
u/glunky_womboI thought this was all already known 😭1
u/Visible_Fill_6699Wait so the ambitious go getters could simply be suffering from brain inflammation?1
u/CatOnKeyboardInSpaceTake two ibuprofen. If your mood improves and you can think more clearly, maybe the reduced inflammation helped.1
u/Wooden_Try1120Compulsive disorders are not impulse disorders. I think we already knew that.1
u/Fun-Birthday-4733Celiac disease should be tested for at birth1
u/ColonelSpacePirateWhat are the bio markers for brain inflammation?1
u/ImAVibrationLikely why the keto diet, which reduces inflammation, is so well connected to mental health improvements.1
u/BaronOfTieveYeah this makes complete sense as someone with OCD; my OCD is 100x worse when I’m stressed or sick.1
u/Lurk-ProwlVery interesting and great work from an Aussie uni to have come out with. I’d like to know how inflammation was measured and how this can be reduced. For instance, skin inflammation can be reduced with drugs like prednisone, but there are side effects. Other people claim that diet helps them reduce inflammation, but perhaps it depends on the cause and area of inflammation.1
u/Ok_Yellow_4862Muscle spasm causes compulsive movement and thoughts. "Working out/unraveling" the spasm so that it no longer controls. OCD behaviors may also decrease inflammation short term, but does sticking through/going all out on the behaviors (as opposed to stopping them) ever result in cessation of the behaviors? I.e. are they becoming ingrained, or are they a necessary tool to reprogram the brain? I like "misguided" being used in the article, bc with other help or support that could "change the overall environment or system" the ocd behaviors may become unnecessary.1
u/Funkmaster74Today's edition of Obvious News.1
u/strawberry_lr/M_Determinism r/Determinism1
u/Formal_Economist7342The word inflammation is used kind of um confusingly here.1
u/Resident-Age-8844Does this include compulsive liars?1
u/archives2024Inflammation is the root of all disease.-1
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2r/Epstein"Canada's Epstein Peter Nygard" & Steve Powers on Stem Cell Technology (SCNT) | ...WelcomeWindsorCastle6290%8580.0stem cell therapy2026-03-05
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u/Honest_Yesterday4435So basically they want to take the traits of black women and give them to white women. This instead of just fucking a black woman because they want to avoid the "black" parts. This feels pretty overtly racist right to their faces. "We don't want you, we want your ass on a white woman."negative204
u/Desperate-Pause6422It’s eugenics. Acid-fashism.negative111
u/shhhImasleepAh yes. Peter Nygard. He also liked to have girls “stool in his mouth.”negative85
u/wheresmystache3It seems like they didn't know eachother, but I did search the files and Epstein says he didn't know him when one of his friends asked. Later on, JE was trying to sell one of his planes and Nygard sent an offer, but JE didn't take it. One of JE's secretaries mentions that Nygard was interested in buying the plane's interior. JE and Nygard had VERY similar hobbies with sexual abuse on islands (Nygard had Bahamas) and obsession with genetics and producing offspring with their DNA. Nygard's obsession was with black women and believes their DNA to be superior. He bought placentas of the women he impregnated (one victim says he offered her 30k for her placenta!!) and had his team of scientists extract stem cells from them for him to inject into himself. Crazy how these two really didn't cross paths, just barely.negative42
u/Strawb_shakeFucking Crypt Keeper over herenegative31
u/[deleted]I’d rather not come across this tonight and ruin my night. They are talking about women as some sort of specimen to use for their projects. He says if they have abortion it’s even valuable as they can use it. This is utterly sick and disgusting. And they record this heinous conversation? What’s wrong with people…negative30
u/OverAmount5551Proof of another franchise in the same sketchy business? ?negative22
u/Chemical-Lab8446This is one of the most disturbing conversations I've seen in the internet in general, and that says a lot.negative22
u/Sacred_SilencioI’m so disgusted. $100 for their egg? This is modern slavery. Bet these white men will force these women to also raise these children without compensation. ?negative12
u/[deleted]What. The. Actual. Fuck. Females are not fucking cattlenegative11
u/silhouette_orchestraThis guy lived up the street from me.. He always had parties with a particular interest in black women. He let several live in the apartment building behind his home.neutral10
u/Financial-Newt2291Didn’t the Nazi’s do these types of experiments.negative8
u/Level_Worry_6418WTFnegative7
u/FewHotel5733Notice they mention about using and consuming everything, yet tip toe around mentioning the actual Baby.negative7
u/LifeAsNixThis is what Epstein was allegedly doing at Zorro ranch.negative7
u/CBLA1785He is Finnish. Not Canadian. We renounce him.negative5
u/mcolette76Bekah Day did a deep dive on this. Peter Nygard was raping and impregnating women so they would abort the fetuses and this ghoul would have the stem cells to keep him looking young.negative5
u/jake_burgerThose guys look like sex offendersnegative4
u/chingy1337What the fucknegative4
u/Apprehensive-Style64Whatttt??? ?negative4
u/KidzinmotionPut these fools under the jailnegative4
u/IamKris7rnHoly crap! Peter Nygard use to try to get young girls in the Bahamas. Fucking creep.negative4
u/Sweet_Strength1120[deleted]neutral4
u/Apprehensive_Eye_530This is actually happening has a podcast episode featuring Peter’s son! It’s him talking the whole time telling his story. It’s a great podcast in general and a good listen! Edited for spelling I got excited lolpositive3
u/cool_girl6540Offering the women $100 for an egg? Total exploitation. Glad the women were savvy enough to know that that was a totally exploitive offer. ?negative3
u/SatirebutinasadwayThis is a fucking "I think you should leave" sketch but it's real. What have they done to us? ?negative3
u/benjaminm_4229Super cringe.. I hope the women in the videos are cringed as well.negative2
u/Large-Mastodon6179Fucking nuts ….negative2
u/Adventurous_Pie6362It's over. Humanity, I mean. Just enjoy the rest of your life as best you can and don't bring anyone else into this world.negative2
u/georgedupreeI said what I said when I said it, our Prime Minister needs to be investigating any and all ties to Epstein and the files up North.negative2
u/ILoveinfo9911Creepy weird sick men👺👹negative2
u/b15d1ckThey damn know how to talk in cryptic languages in all these files...negative2
u/Gabagool1969A family member worked directly for Nyguard’s fashion company in the ‘90’s (fam directly reported to Nyguard). Fam wasn’t looped into to any of his crimes, but said Nyguard was a horrible person and boss. Example: Nyguard demanded shitty company policies, like that work-related air travel had to be done outside of normal business hours (on nights/weekends). Nyguard’s secretary booked all airfare to ensure flights adhered to this policy. Also - Nyguard once settled with a woman that was bitten by an emu at one of his “feather parties”. Nyguard personally invited employees to these parties by gifting them a “feather” & invitation. Fam was never invited to these parties, but mentioned they happened at Nyguard’s SoCal residence. After fam quit, Nyguard went out of his way to rat-fuck fam by giving him shitty references.negative2
u/BSTARYOUNGGYukkkkkkkkknegative1
u/Sterlingsgma1ALL MY CHILDREN??😓💔😡🤬 ?negative1
u/MarinaEnnaObjectifying them in the worse way possible, and trying to pass it out as a complement 💀negative1
u/Mundane_Front659All of the transcripts of what these guys and other rich people and politicians used back then for private communications was on ECHELON and will probably never see the light of day without massive public outcry because it's a tool still used by rich people today to manage their lives through their government connections, especially the Rothschilds.negative1
u/Spicy_Pickle_6Disgusting conversation at the table wtfnegative1
u/babyblew82Why was ONE of the broads not blurred out? ?negative1
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3r/InterstellarKineticsEXCLUSIVE: Scientists just discovered a protein that reactivates stem cells in a...InterstellarKinetics17510%3979.4stem cell therapy2026-03-20
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u/InterstellarKineticsThe DMTF1 finding is compelling on its own, but the bigger story is what it represents in context. Three years ago, telomere lengthening in living humans was theoretical. Today there is a human clinical trial showing an FDA-approved pill does it, a Stanford study showing stem cells can be rejuvenated with a single molecular exposure, and a Harvard scientist standing at a global summit saying aging is reversible. The science did not inch forward. It accelerated. Do you think we are within 10 years of a clinically approved anti-aging therapy that measurably reverses biological age in humans?positive31
u/EmberMelodicaIve been saying to people for a while, my generation will be the first to see immortality. Whether it's through biological advancements like this, or through technological replacement.positive16
u/SteambunsinvasionOh , dictators will live longer now…negative12
u/VoodizzyCan this apply to dogs? ?neutral9
u/ahmtiarrrdCue billionaires ensuring they have exclusive access to therapies based on this breakthrough in 3... 2... 1...negative7
u/baycentersDMTF1!1neutral5
u/poopinWell, this would explain why billionaires are building bunkers.negative5
u/bardmalliardSo what vegetable am I supposed to eat to get this? ?negative4
u/Whatislifeabout24Does this also work on TBI? ?neutral2
u/wvuroxxLet’s goooopositive2
u/Mooseguncle1No one here thinks this is how we wake up to a zombie outbreak?😷 ?negative1
u/OMGWTFBBQBRTStoked to see the story 2br02b come into fruition!positive1
u/Candid_Koala_3602And the replicators level uppositive1
u/opalvegWho wants an increased rate of brain cancer? ?negative1
u/derpindabAs someone with MS, I will take two. Thank youpositive1
u/beyondbarrelsso eat more protein bars? ?neutral1
u/Opening-Winter8784This is nice and all, but can we not.negative1
u/Hungry-Ad7987Suddenly your mortgage extends to 300 yrs.negative1
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4r/MultipleSclerosisJOHN HOPKINS UPDATE!Emotional-Mud-86843090%8276.8stem cell therapy2026-03-12
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u/mullerdroolerThanks for sharing but one thing I want to dispute about diet is (if you can't pronounce it, don't eat it) Psudo scientists and wannabe gurus often say things like this but often simple ingredients like salt or vitamins have their scientific names on ingredients. Just coz you don't instantly recognise it doesn't make it bad. Do a quick Google search of ingredients then decide. It might be a nasty preservative or a simple healthy thing your body needs.59
u/Material_Sundae_5832Thank you so much.. this means a lot. You reported back very quick. And looked and took time to respond to all the questions. You are a very kind person.51
u/MoonElf19Also RE effective medication on the market: it's spelled Kesimpta (ofatumamab) It's what I'm on, happy to hear it's a top suggestion!11
u/HerBonsaiGirlI find that research hospitals tend to be the most dismissive of the lived experience of smouldering MS.10
u/spunkerella75Thank you for reporting back and so fast!8
u/worried_moonThis is so interesting! Thank you for managing to answer so many of our questions when you have a lot on your plate yourself. I’m going to stop worrying so much about my Octave results - if John Hopkins doesn’t care about it yet, maybe I should boot it from my headspace. There’s not a lot of extra room there anyway. Smoldering MS is def a thing, but not everyone talks about it that way. Some say PIRA. It’s definitely an issue - and maybe THE issue for me at the moment - but I can understand why it’s not discussed at your first appt. And…they don’t really know what to do about it anyway, aside from the great advice that they already gave you (strength training, DMTs, etc). Thanks again for doing this for us!7
u/LaurLoeyhttps://youtu.be/IaCdmu61T8k here is my neuro talking about octave. i found him when i googled his work. 😂 now i know these big conferences are a thing….6
u/EthyrumThank you. I’ve gone to Hohns Hopkins MS center for 10+ years and have been happy with the care. The answers to the questions you posted sound similar to what my neurologist there would also say. He said the octave test is a bit too new and doesn’t have the standardization yet for it to be meaningful. I trust what I’ve been hearing from this MS center and feel like I’ve received quite good care. My neurologist there are also answers any messages I send through the portal quite quickly.6
u/Roger_VandenbergheWould have loved to hear their opinion on everything gut health related and spinal fluid transplantation. Like one of the potential therapies i imagine in the future is having your intestines cleaned off any bacteria that's involved in ms (like they do presently for a colonoscopy, the laxative green fluid they make you drink) then transplant a health donors compatible stool. And the chemotherapy thing, i keep on getting about in relation to ms. Basically they kill all your spinal fluid (where your immune cells are made i'm guessing) and again introduce a healthy compatible donors spinal fluid. Also if EBV is suspected to have such a high correlation, you would think a vaccine would be the number 1 priority in these research focused hospitals, no,? Thanks for sharing with us.5
u/MoonElf19Thank you!5
u/Master_Caramel5972Thank you a lot ! I'll look into strength training, I would not have thought it helps with cognitive issue5
u/Did_ya_like_itBless your heart. So kind of you. Love the response to smouldering MS- so fast. But space and time 🤯5
u/Reasonable_Life4852Thank you for sharing!4
u/Isitoveryet_50This is awesome thank you so much ! I'm glad you added that about peptides and sleep. Both both are issues I'm dealing with right now and someone I know is urging me to try peptides as it works for so many things and wants me to get them from Russia. But.. not wasting money on something that no one thinks is going to work. And help for sleep? Thank you for that I will try the Magnesium 2 hours before bed because I don't want to feel groggy when I wake up. All of this is really awesome thank you for sharing!4
u/No-District-9322this is what i needed to read to start seeking strength training. I was thinking it would get my fatigue really worse, but now im considering at least to give it a try4
u/[deleted]Thank you!3
u/PK5002Thank you very much. It's so nice of you to share all this information.3
u/berrattackThank you3
u/NicoleR_24Thank you so much for taking the time to share this. It’s because of people like you that cares so much that can help find a cure for this one day.3
u/buderfwyThank you so much for sharing!3
u/Soft_Cash3293Thanks so much for reporting back 🙏🏻 love to hear about strength training, it's something I really enjoy and it's great to know it's good for us with MS3
u/Many_Theme4441Great post. I’m a lurker reading everything as I’m newly diagnosed. Thank you for taking the time to share the information from your appointment. I hope your appointment personally went well.3
u/my_only_sunshine_Ugh sucks that the one I was most interested in is the one with the shittiest answer (smoldering MS)3
u/CheebissThank you for posting these responses! My husband just had his first outpatient appointment yesterday and the 90 minutes went by so quickly we didn’t get to ask everything we wanted so these responses help! For your eye, did your neurologist mention trying to treat it again before starting a DMT? My husband’s optic neuritis hasn’t totally gone away and he hates steroids so they’re actually going to have him do plasma exchange. They’re basically going to try to rescue as much of his vision as possible before starting the DMT.2
u/chunkykimaThank you for doing this! Saving this thread to come back to and remind myself of those answers.2
u/Kelevra7_Thanks!2
u/Drbpro07Thanks a lot for sharing2
u/No-Establishment8457Thank you for this information! Even as an MS patient for 35 years, always something to learn. Appreciate you.2
u/sunshine_59_Thank you!!!! You're the best!!2
u/mr_bearculesVery interesting and informative. I’m just starting out on my MS journey and so this info is helpful.2
u/raptordamusThank you for sharing, appreciate you!2
u/Thereisnospoon64Interesting re Melatonin. My neurologist flipped out at me when I told her I was on it bc she said it’s completely unregulated plus it causes bad hangovers in the morning. I’ve been on Trazodone for sleep ever since and it’s been great.1
u/LizzieBourbonAwesome! Which dr did you see? Mine isn’t super chatty, but he responded to my MyChart question within 5 minutes today.1
u/No_Consideration7925So you were just diagnosed. I’m so sorry. Yeah there’s a lot of information out there. Hang in there mind your sleep and healthy daily habits, especially with eating lots of nutrients. Xx1
u/No-Armadillo-7393Strange question, still new to this 8 months since diagnosis but what are T-Bands in spinal fluid? I had "O" bands in mine🤷‍♀️1
u/asap_stockyWhat is the eye thinning about? I’m confused1
u/Broman400You lost me at your response to stem cell therapy. It is 100% better than a dmd for a lot of people. AHCST stops disease progression and lasts for years1
u/FewProgress1797Thank you for this. First symptom optical neuritis1
u/NativeSJThis should be pinned for newly diagnosed folks. Well done!1
u/sonoallieWow! Thank you so much for all of this!1
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5r/immortalistsMore people will want to live forever if and only if they can live forever young...GarifalliaPapa2720%8176.2stem cell therapy2026-03-15
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u/ImDeepStateI can look 50 if I get to live forever.63
u/AttorneyUpstairs4457It’s good to take a moment now and again to remember that it’s only people who have the opportunity to age who actually see aging as a problem. Aging is of course also a privilege that we won’t all have.32
u/Repulsive_Falcon_408If only there was a way to pass down our biological information into a new body that inherits everything we are, yet begins with every cellular process fully restored...14
u/GenuineHMMWVDon't worry, if we don't figure it out and have to die... it won't matter anymore 😃9
u/smart-monkey-orgAnd you can actually help by growing the community - joining r/immortalists and bringing your friends along!7
u/moonracersMost, depending on their age will get their wish. 150 will be the norm, sooner rather than later. In order to truly live for hundreds or thousands of years will require us to toss these bags of water we call bodies. IMO anyway.6
u/TiltedbrimboyScience advances one funeral at a time6
u/MissAmberRI’m 50 already I’m not sure they are going to figure it out in time to save me5
u/Available-Mail-8264Couldn’t care less what age I look if I have the physical and mental fitness I have at 385
u/EnvironmentNeith2017Kind of off topic but aesthetically I wouldn’t want to look 25 again. I find middle aged looks much more attractive.5
u/parkerkudrowI would want to live forever if the planet wasn’t dying and everything wasn’t getting more expensive and worse. What’s the point of living longer if quality of life is horrible?5
u/Antique-Resort6160Honestly i could be old looking, i just have so much I want to do. Another hundred years or more would be great!4
u/OwlKitty2Who cares about looking 25, it’s how you feel that’s important. Living until 125 and feeling 125 would just be a cruel and unusual punishment.4
u/Huge_Line4009I imagine you would also have to work longer, right?3
u/_FIRECRACKER_JINXyou'd think so, right? I don't think it would work that way. Because TECHNICALLY SPEAKING, we ALREADY have a few anti-aging medications called "vaccines". They technically prolong your life, reduce the amount of stress that your body goes through by preventing preventable diseases/infections, and limit the amount of damage your body sustains from preventable infections like COVID, Flu. yet here we are, with a huge HUGE segment of the population being proudly Anti-vaccine. I think if an anti-aging cure was invented. People would respond to it, the SAME way they responded to the COVID vaccine. WHICH IS A GOOD THING, IMHO. We do NOT want the dumbest people living forever, we really really don't.3
u/MrGhost899Ruuuuun!2
u/MegaManSELooking young is actually way easier than actually medically reversing aging. Many Hollywood / politician types already have these techniques down.2
u/Melodic-Berry-8635Are we being hyperbolic with the living forever statement? I can see people wanting to live to the high hundreds or possibly longer if they could be feel/look like they are 25. But seriously who the hell actually wants to live forever. I'm not suicidal, and have a pretty decent life, but I would have been cool tapping out of this world a decade or two ago. I mean there's really only so much you can see or do in this world. Let others have fun playing with this puzzle box2
u/saymellonIf we could somehow get a 125 year old person look like 25, then everyone would want to live forever.  That's a pretty stupid thing to say, though. Why do you think some people in their twenties commit suic***? Not everyone wants to live forever2
u/sakraycoreYep my goal is to look like I'm around 25 years old forever. Basically my longevity stack in a nutshell.2
u/Emergency_Incident32Nah, I will embody the crone phase of life and keep it that way. Aging is a privilege2
u/El_Loco_911There is no self i am mortal and eternal2
u/totoin74Every death would be an accident or a murder if aging got eradicated.2
u/Emotional-Dog-6492You can’t DEFY ageing. Its a genetic program. You can only slightly expand or shrink it2
u/stomachofchampionsProblem is you would become more likely to die from an accident.1
u/ReadwhatudisagreewitAnd what do we do when hundreds of millions people can live well into their 3 or 4th century’s, while populations swell into the hundreds of billions? Somewhere along the line, procreation would have to be restricted.1
u/BriannaPuppetI think that what is actually going to happen is that large numbers of people will have to confront the fact that they hate themselves and can’t wait to die Fortunately, they will have plenty of time to work that out1
u/JonaEnyaI'll fix it1
u/hordak666I want to look like Saburo Arasaka and live forever.1
u/WordPlenty2588When I see this photo I think of sun related aging https://share.google/sgQxfauOCWr2sP0uZ Sun is very good for you, we need D3 and other things... But too much sun is bad1
u/aspiringimmortalAging is barrier number 1. Religion is barrier number 2.1
u/MrGasMan86Nobody wants to live forever. That’s not what life is about. There is no game genie you can just hack life with to live forever and even if you could, nobody would want to. Life is short, delicate, and precarious for a reason. Enjoy what you have TODAY and forget about tomorrow because regardless of anybody says about the future, our time here is limited. Acceptance of that will go a long way for your wellbeing AND your future.1
u/Willing_Progress_646I think also sometimes life sucks so that also plays into ppl being ok with marching towards their death everyday...1
u/Sure_Assumption7857lol, no.1
u/Origin_64The age gene has been found for a while now….if you couldn’t live forever, what age would you want to live to, assuming you still look 25 haha1
u/Independent-Sense532This seems a bit delusional.1
u/SuddenAvocado35 and started taking my metabolic health seriously this year for this reason. I know I won't get back exactly to where I was at 25, but I want to feel good and strong for as long as possible, and if I can capture right now, that will be good enough. I think the biggest difficulty is illness. Even the most fit and healty people can get a serious infection or disease- or even stressful periods- and be knocked out for months or year, and then struggle to return to their previous fitness. This was my case in my early 30's and I fear it will happen again in my later life.1
u/ConfusedGuayabaTrue1
u/Fluffy_Nuts4120if my aunt had balls she'd be my uncle1
u/DrawingCivil7686[deleted]1
u/MrBodaciousMakerIf there was no religion we would have figured out immortality long ago.. but nooo people think there is a magic world after you die instead of just nothing so death is ok 🤦‍♂️
u/Constant-Chance-5245Imagine how horribly overcrowded the world would be and the shortages of food and housing and the strains that living so long could cause…….
u/PsychologicalMethod6I personally think it would be a curse to live forever and even if I stayed as fucking good-looking as I am right now I'd still want to die and see what's next
u/Odd_Spring_9345I don’t think I’d want to live that long with the way the world is looking-1
#SubredditTitleAuthorUpvotesRatioCmtsScoreSentimentKeywordDateLink
6r/TheRaceTo10Million$SLS (Deepest Due Diligence for SLS-009, Machine Learning Models and Results, an...Confident-Web-71181790%9674.9stem cell therapy2026-03-16
commentercommentsentimentupvotes
u/Even_Armadillo_634Me who trades on vibes: sounds good, buying more!57
u/cuntysometimesWow, as someone holding SLS due to conviction from galinpepimut-s (gps) research, thank you for this deep dive on Sls-009. Don’t have the time now but will def be back for a deep read. What are your thoughts on gps phase3 trial?26
u/ModelingDenver101SOB, I'M IN!!21
u/astroworldddBabe wake up new Confident Web DD just dropped17
u/The_Pixel_KnightSLS and IBRX were the first stocks I bought. Now my only 2 stocks. Just over 1000 shares in SLS. Im not exactly rich, so this could be life changing tbh. Wish I knew a ballpark timeline. Debating whether to invest more.15
u/Snoo-90236Ohh god Nooooooooo!!! Please for the love of god stop it with the DD. Everytime I see one of ur DD makes me wanna add some more. I already full ported this shit. And I got no money left bro. Im gotta sell my ass soon, or work extra behind Wendy's dumpster. Fukc11
u/Lowlander-b9Was hoping you would tackle SLS009. Thanks - look forward to reviewing.8
u/Consy98Was previously an SLS doubter, and never really had a large position but I’d never come across your posts but this has completely cleared any doubt I had. This post and research is incredible. Thank you so much. Opening a large position in the AM. Thanks again!8
u/Fragrant_Persimmon_8You dirty dog, I'm in! (For 1000 more shares)7
u/KirklandJoshLegend7
u/redditshelley1Amazing resource! Thanks for sharing!5
u/Dagobot78I’m up big on SLs… i sold 1000 shares last week and bought $7 options for Jan 20275
u/TestoWenzxRemindMe! 1 day5
u/currysoup19RemindMe! 365 days5
u/Consy98Was previously an SLS doubter, and never really had a large position but I’d never come across your posts but this has completely cleared any doubt I had. This post and research is incredible. Thank you so much. Opening a large position in the AM. Thanks again!4
u/Ambitious-Dark-6321OP maybe a stupid question but if the 80 event annoucemend still takes longer en longer does it still improve the hazard ratio or has is halted. Sorry for my English it is not my first language.4
u/bmarvin35I’ve been in since$4. Holding 7000 shares so far4
u/dirksqjawOverall, brilliant DD. Honestly one of the best I've seen in biotech. You lost me at the %99.99 thing though, that's a conviction statement disguised as math.The model is good enough to say "probability of success is meaningfully above the base rate for Phase 3 oncology trials". It is not good enough to compress the failure probability to 0.01%. Saying a blinded Phase 3 cancer trial has a 99.99% success rate isn't doing science, you've started writing fan fiction. Just to pump the brakes a little here, note that the control arm problem isn't addressed. What if VEN/AZA in 2024-2025 (the REGAL control arm's actual treatment era) produces 14-16 month median OS rather than the 6-8 month historical baseline? That would compress the hazard ratio dramatically even if GPS is genuinely extending survival. The cure-fraction model uses historical BAT priors. If the actual control arm is outperforming those priors, the HR prediction becomes unreliable. Don't get me wrong, I HOPE you are fully right, but I'm playing this like a typical biotech binary play. This is still a casino.4
u/PrettyStatistician29RemindMe! 1 year4
u/steadyeddy_10Thank you for the insight!3
u/ProfessionalDesk1914thanks, appreciate the sls dd and will read a few times. did notice you listed the market cap as 494m when it's roughly double at current share count and around ~1.16b fully diluted.3
u/mad_papooserI think if GPS pushes later into Q4 or Q1 of 2027, we should have early data on SLS009- I'd think it would lean more towards an all-cash deal vs cash plus CVRs.3
u/Just-Finance1426Amazing DD as usual, thanks confident-web. I have a couple questions though - why is SLS running a phase 2B trial for SLS009 instead of moving directly to a phase 3? And why did SLS set such an aggressive primary endpoint of HR < 0.63 for GPS? It seems like they would have achieved statistical significance with a smaller trial, or been able to conclude the trial with fewer events if they didn’t aim so high - I’ve heard that HR < 0.8 is generally sufficient to get approval.3
u/Roffles85Another one for me to read, thanks. Just out of interest what is the average cost of your shares, thats a huge investment…3
u/Accomplished_Way8964Thank you. My big fear at this point is the FDA decides the REGAL results are too good and ask them to run the trial again. Sounds preposterous, I know.3
u/Accurate_Pay_2242For the BO3
u/lndnmdnholy yaparoni3
u/lardarzAlright clever clogs, I'm in3
u/JoeAceJR20I have a DITM call for sls3
u/Intelligent_YoloerI’ve gone through all the DD and the comment threads on confident-web’s posts, and I still haven’t seen anyone clearly disprove the thesis with solid numbers. This man has exceptional talent in ML and statistics. This is still a binary play, and anything can happen. I will not go full port. I’m in with about 30% of my port right now, slowly adding in more shares with the gains from my other stocks.2
u/RaichuCakeOh please give us a $100 each share buyout2
u/My5t3ryLots of words and pictures. Im in ! Thanks OP2
u/carpool4445Solid DD as usual. Have a question not about science but about politics. If the war in the middle east drags on, what would happen if there were to be a global recession and wider stock market decline. The strait of Hormuz being shut down halts 20% of global oil, 33% of global fertilizer. How would this affect a buyout?2
u/Physical_Package_34020% of my portfolio now! Should I add more OP?2
u/SteveMcHeaveThanks for all of your hard work here. Is using 53 AML trial cohorts enough for statistically significant ML results? The sample size of patients also seems way too low for definitive phase 3 clearance. 99% chance of REGAL being a go seems a bit excessive.2
u/Consy98Was previously an SLS doubter, and never really had a large position but I’d never come across your posts but this has completely cleared any doubt I had. This post and research is incredible. Thank you so much. Opening a large position in the AM. Thanks again!2
u/1fortheroad24theshowMuch great data, much that does not make sense, at least to me. Several factual errors, herein, only to quibble, RPPR Vouchers, last 3 or 4 sold for $205M not $100. VINC VIP150 was the Most advanced CDK9 prior to Tambiciclib, its absent from your analysis. I Saw no discussion of the many fda apprved Kinase inhbitors. Tambiciclib P2B results for the AML-MR patients on optimal dose was not yet reached, so it will be longer than the 8.9 months you scaffold much of your data. In attempting to simplify, the OCT webcast has a very detailed analysis, from the Dr's trialing Tambiciclib, and underscores yours analysis, Tambiciclib will work better in Front Line Setting, than the refractory environment from the P2b, which ensures its approval, as the p2b data is already better than the current SOC AML-MR CPX-351. Thank you for the exceptional Due Diligence/2
u/BigPharmaSLSWHAT IS YOUR POSTING NAME ON STOCKTWITS?2
u/carpool4445Separate question pertaining to the REGAL timeline. In a separate thread, you argue that the models project it ending between October 26 - March 27 or even later. However I have heard it argued that REGAL is due “any day now”. This thread has run4theroses’s DD (https://www.reddit.com/r/sellasLifescience/comments/1rdp2sw/comment/o7qra8n/?utm_source=share&utm_medium=mweb3x&utm_name=mweb3xcss&utm_term=1&utm_content=share_button) and he argues that events are not linear and that REGAL results are imminent. Do you mind breaking down his claims and your own projected timeline more? I’m trying to resolve these competing arguments in my head but do not know enough science/stats to do so. also you might have to dig around in that comment section. A lot of comments were deleted so his DD is buried in a long comment chain1
u/carpool4445I am debating calls and thought I'd ask. $10 calls for Jan 2027 are a safe play yea? Because if REGAL doesn't end, the results from SLS-009 in Q4 will definitely spike the price above $10.1
u/Content-Resource5887Still early for a lot of these models, but they’re definitely worth keeping on the radar.1
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u/Upstairs-Zebra633And that matters
u/Reasonable_Cow3667slop-1
u/Leading_Form_8485Puts. Im dead serious-1
u/cyrustwoCan you PLEASE buy DRTS too? and ASTS? and RZLV?-1
u/SnooChickens561Always inverse Reddit — buying puts!!-1
u/Scary_Culture3768ummmmm I just farted-5
#SubredditTitleAuthorUpvotesRatioCmtsScoreSentimentKeywordDateLink
7r/alamedaBEWARE raw milk! New vendor at the farmer's marketrubysolomon1700%10174.8stem cell therapy2026-03-25
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u/AlamedaRaisedYes that's bad. I thought this was an Indian-owned business because of the name "Desi Milk." Turns out it's a white lady named Desiree, so Desi is a nickname. But on the company website it says she's been in the homes of hundreds of Desi families (South Asian families) through her arts, so she's actually co-opting the "desi milk" term from this community. "Desi milk" refers to milk from desi cows that are native to India, it does NOT mean raw milk. Most Indians do not drink raw milk, and most of those that do boil their milk first, due to not having access to pasteurization. This person is making it sound like a cultural thing and it's not. This needs to stop, both for public safety reasons and for cultural sensitivity reasons.141
u/ShoesietartThe level of stupid at the federal level is staggering.29
u/Abba_FiskbullarThis man has done heroic quantities of hard drugs, so he knows what's safe for us!26
u/contactdepartureDesiMilk posts this on her IG, but sees no irony in it... https://www.instagram.com/p/DCnG784ynmo/?hl=en Uhm...13
u/StracharysHere come the MAHA warriors who don’t understand about human breast milk vs cow milk or anything about farming practices. They will have statistics that don’t actually make sense, but they have done their research!13
u/Rolling_PugslyThe comments visible are nuts. Tin foil America. Edit to clarify: The comments in the IG photo praising RFK are nuts.10
u/Zealousideal_Help421I was there on Tuesday and overheard her saying to a customer that she likely won’t come back because the Alameda market is so slow and she’s a few hours away. Let’s hope.8
u/snickle99Yikes.7
u/heyitscoryIf you hang a sign that says "get a new clock" on the stopped clock, it's right all the time.7
u/LadyBrady66They take medical advice from someone in the Epstein files who did coke off a toilet seat. No surprise.5
u/Technical_Fix_706I wonder if these people believe they’re innately better informed and more knowledgeable than the highly educated & experienced in all fields of study & areas of expertise or just those associated with science & medicine? For instance, if their transmission starts slipping, do they run to the feed store for some horse dewormer or do they defer to an auto mechanic? If a grease fire starts in their toaster oven, do they sprinkle some peptides over it and douse it with raw milk? Are they the reason those tiny packets of desiccant have the phrase “DO NOT EAT” printed on both sides???4
u/Any_Administration17Yikes3
u/Kill_Bill_WillShe’s probably anti vax if she’s peddling raw milk too, yikes!3
u/rubysolomon<image> OH DEAR2
u/moth_candelabraThanks for the warning 🤢 these kooks are a public health hazard and should be treated accordingly.2
u/chrisfsDefinitely not good at sll1
u/gsanch9There’s a war on exercise everyone
u/Opening_Big4569this is not a place of free speech, has reddit always been cultish?
u/wwarrHow much raw pus is too much? In California and across the U.S., the legal limit for somatic cells (white blood cells, often referred to as pus) is a maximum of 750,000 cells per milliliter (mL) of raw cow's milk. This limit is enforced to manage mastitis, an infection, though typical herd milk often has much lower concentrations. What are Somatic Cells? They are predominantly white blood cells produced by the cow to fight infection or bacteria, particularly mastitis. Regulatory Standards: The FDA sets the limit at 750,000 cells/mL. If a bulk tank exceeds this, the milk cannot be sold for human consumption. California Specifics: California generally follows national regulatory standards, with the Milk and Dairy Food Safety Branch (MDFS) overseeing milk quality.-1
u/justid_177What do you mean by “beware”. Do they sell raw milk and claim that it’s actually not?  It is legal, and there is no reason for disparaging a legitimate business. You don’t want it raw, don’t buy it. Simple-7
u/Rich_Gap3429I actually bought some of this milk yesterday and it was delicious—definitely a high-quality product. At the end of the day, it’s a legal product in California and the beauty of a farmers market is that we get to choose what we buy. If you aren't comfortable with the risks or the vendor’s personal views, that’s fair—don't buy it. But I don't think we need to 'cancel’ a small business that’s following state regulations. Most people don't realize that many common foods like raw oysters or even bagged spinach actually carry a higher statistical risk of foodborne illness, yet we don't try to cancel the grocery stores that sell them. We’re all adults who can make our own informed decisions based on our own risk tolerance. If it's not for you, just move to the next stall!-15
u/Tommy2212222What is this? They’ve been selling raw milk at California farmer’s markets for as long as I’ve been going (2009). Shame RFK has spoiled the name of raw milk. In my experience it has been great, love the taste. Also just moved back from EU where it is relatively available. Not sure why you’re here rage baiting and disparaging a small business?-33
u/OhShitAnEliteOP you’re gonna wanna sit down when I tell you what you drank as an infant…-62
#SubredditTitleAuthorUpvotesRatioCmtsScoreSentimentKeywordDateLink
8r/pennystocks$SLS (Deepest Due Diligence for SLS-009, Machine Learning Models and Results, an...Confident-Web-71181650%13174.7stem cell therapy2026-03-17
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u/outdoors_life22You sir have made the longest Reddit post that I have ever and probably will ever see53
u/CHE-B5Pfoh you accomplished a lot but men, that is a truly a though, technical read haha42
u/Yung_CeejayGreat post! This is still my largest holding!23
u/Practical_Ad_5875I’ve full ported this, could be my biggest regret or biggest achievement19
u/Muted-Extension-852117
u/Regular_Hawk8513I only have 120 shares, but I'm looking forward to what they become.16
u/Urkel____grueThanks for another great DD post. I am a big believer in $sls and hold five-digit worth of shares (and buying more when I can). I see your posts a lot and follow you on Stocktwits. I really do appreciate them very much, and have read all of your posts. The only two things that give me pause about your posts: you clam to have 800k shares. You don’t owe use anything at all, but can you share proof of holdings? That’s an insane investment and you must have more conviction about this stock than of any stock you’ve ever held as a DVI with that amount riding on a single stock. Secondly, if the math shows 99.99% success rate for just REGAL, what aren’t investment firms pouring hundreds of millions into SLS if it’s so surefire? I know there’s a lot of interest from investment firms but there’s not $1b+ pouring in. It can’t possibly be so surefire as you make it out to be Thanks again - I don’t want my slight skepticism to outweigh the due diligence you’re sharing. It’s just, the amount of shilling from an account that only shills about a single stock raises flags for me. Cheers14
u/Playful_Criticism425What the helly.8
u/Used-Motor8283I'm balls deep in SLS8
u/Confident-Web-7118I am an SLS holder. I personally believe that SLS will have a premium with it essentially becoming an AML monopoly in the best case, with some platform optionality. My best guess would be somewhere in the 3-8 billion range. Perhaps higher if results are exceptional. But any ideas that SLS buyout will be in the 20 Billion+ range is folly. That would essentially make SLS worth around the same Moderna and BionTech, which have a platform proven for multiple indications. Sellas at best has two indications without further research/development. For a company to conduct many, perhaps dozens of clinical trials to truly create a platform, it would take billions of dollars in RnD. That is why they will offer a discounted price to future potential.6
u/Federal-Snow1914Really appreciate this and your other posts. I’m heavy into $SLS as well. A few questions to hep me understand your confidence for you since I can’t fully grasp all of your analysis: Have you ever been this confident in a stock and missed the mark? What percentage of your own portfolio is in $SLS? Are you betting the farm? Thanks again for sharing all of your work!5
u/MaxTrade84As someone who went through treatment for Leukemia (not AML) I appreciate the depth of research and am now a shareholder. Thanks!5
u/Tantpispourtoi5
u/ambassador3215
u/National_Major_9356Holy... this is impressive. I really apperciate your work. I can't even argue with what's been written, so I have to go in with a small position; I'll be watching this very closely.5
u/SavingsMortgage1972Frankly, I didn't read any of this so I have no idea if you overfit your models to hell but you convinced me to put 10 racks into this lets print money.5
u/Accurate_Pay_2242Holding for the BO4
u/altiifGod, I hope you’re right. I have 4400 shares at around $2 based on a random post I saw on Reddit. Definitely have made money but am holding on for the long haul. Amazing analysis and work that you put in - even if it doesn’t end up being correct. I admire the dedication and level of nerdiness.4
u/BehemothslayerTLDR, what’s the ticker that I’m buying??4
u/sterculese89I caaaaint reaaad4
u/PhebreGreat work, thank you3
u/BariBlueYou are a very intelligent person and I do my best to read all of your DDs to get even more of an understanding of what we own. With that being said I’m curious in what you do for a living if you don’t mind sharing or can give vague details. These models and over all DD is some of the best I’ve seen since being in the market the last 7-8 years. I know there is no such thing as a sure thing, but you’ve convinced me this is. If the 80th event occurs earlier than expected let’s say Q2 for example. Will the stock run on the great news or will there be no movement until a buyout is officially in discussion? Thanks for all the hard work you do and hope you can answer my questions if you have time.3
u/Desperate-Ring12😎😎3
u/Antonio-BamaoI am in. And I think you can publish one SCI paper using these meta-review data😊😁3
u/Admirable_Ad5134this is insane. props to you man. great work <33
u/Low-Childhood-748Its an incredible analyses, and u are to be congraulated for all the work you put into it. What was not factored in was the testimony of the leading enroller-of course that is not math, nevertheless its important. Dr. Tsirgiotis is convinced that the extended survival being seen is due to the GPS effect. He already explained that his patients were experiencing a better QQL, which makes sense since GPS lacks the cytopenias cuased by hypomethylating agents. Interestingly on the last KOL call, he pushed to study GPS in post transplant maintenance. An academic Hematologist would not push for this unless he was convinced of the effect. Moreover, 2 weeks ago we saw a linked in exchange between a Myeloma KOL and the CEO again where there was interest in evaluating GPS in the MM maintenance setting. My expertise was in KOL management and behavior, and I have a robust amount of shares, but what are the limitatons of the machine model? Could one argue that at the end of all this analyses, the model only has predicted the direction of the survival benefit???3
u/Ateyo94If regal fails we probably won’t get much out of sls900 right? When do you predict the 80th event will happen2
u/TheGoodSaladYou've mentioned a lot of positives, is there anything to be worried about/ anything that could throw this out? No matter how unlikely2
u/Ok-Rock7488I have thousands of shares. I want to buy more but I’m also building into another biotech that I believe will return good results. It’s about choice. Which do I top up. Probably going to let me sls position ride. Good luck everyone. Especially the patients.2
u/Interesting-Play-489Anyone who hasn’t seen the RD video from last fall and witnessed the giddy joy of Dr. Kahn as he talks about 009 should really do so.2
u/kroefRemindMe! 18 months2
u/[deleted]Well researched and thought out. Well done!2
u/Deep_Development3814Do you envision 3.50 could be an entry point?1
u/Low_Sheepherder7990My one and only critique of SLS… your buying a lotto ticket and waiting for a buyout. It will guarantee make you money… I have no doubt there. But in 5 weeks? 5 months? Two years? That unknown timetable and opportunity cost keeps me from going heavy on this one.1
u/Tom9274Firstly, thankyou for your efforts here. The time you've put into this is truly appreciated. Secondly do you have a Github repo to share? I feel I'd probably learn a lot going through your code.1
u/moreheart3Thank you so much!!! Are there any other pennystocks where you see a similar potential and evidence behind it? I‘d appreciate your insights🙏1
u/kroefRemindMe! 1 day1
u/shinigamislikapplesOh fudge that's deep1
u/DawctorMeNice DD again. You mention Keytruda as a potential trajectory, but not as a potential GPS partner. Merck and Sellas did the PT resistant ovarian trial, where merck supplied Keytruda for the trial. Do you think there's potential on Merck also being interested in (atleast) GPS? Biologically the PD1 + GPS combo seems like a good pair. Sorry if you've adressed this in your other posts or comments. I might have missed it, perhaps not.1
u/ExpertMycologist8149Alles gut aber schlussendlich ist es eine hochriskante Aktie. Das muss man eingestehen.1
u/Pretend-Comfort-2569Hey OP, I’m not biotech native in anyway and ran all your DD through Claude and this was the output. https://claude.ai/public/artifacts/91d890dc-e4cb-4d9a-8682-289b676cbbe3 Would appreciate your response to the following points that highlights skeptics. Thank you :)1
u/rockhao781Can you teach me how to build your ML models?1
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u/iplay4HimWell done. I have an off topic question. My biggest concern, legitimately, is AI. I truly believe AI is about to change everything in the next 12-36 months as it quickly passes human intelligence. If that does occur, not only will it have been a better investment than almost anything, but it could render most modern medicines obsolete as it creates more effective medicines overnight. Any thoughts? Just curious.
u/Better-Salad-1442The amount of these types of posts on this specific name is among the most bearish signals I’ve seen-3
u/Delancey1From 200k to penny, no thanks-7
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9r/immortalistsDon't die from Alzheimer’s and other dementias. Here are the most scientifically...GarifalliaPapa2530%4473.9stem cell therapy2026-03-15
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u/whatrumimeansThis article can only have been written by men 🙈 The most important thing is missing - hormone replacement therapy in women.15
u/Keji70gsmStop catching Covid. Seriously, it has been shown again and again to impact brain and cardiovascular health, even if vaccinated (but vaccinated is better), even later variants. Viruses in general are not given enough respect for the cumulative damage they are causing, but covid is particularly nasty for how many body systems it impacts even if it feels like a milder infection.14
u/abrandissorry to burst anyone's hope but most dementias are idiopathic (no known significant cause) and no specific pattern of patients,sure a few cases do have a strong genetic component (Like Chris Hemsworth who has two copies of the APOE4 gene variant (one from each parent). Increasing his risk... The only sure thing we know about Dementia is they are age related (no one under 40 gets them) , so obviously some aging degradation of the cellular mechanism is ultimately the trigger, but the chain is complex and can be influenced by a wide variety of factors . The worst part of dementia is by the time your diagnosed it's too late, there's no effective treatment it's really one of those diseases that you can't do much about other than enjoy life until you can't..12
u/drafzulI advise APOE testing in all my patients with any family history to dementia, not a guarentee of course but prevention is always better and if they have any risk genetically they suddenly start taking advise, exactly like yours here, much more seriously3
u/FrewdWoadHow about that 40hz tone thing? The science on that is new but pretty promising, no?3
u/Ok-Highway-5247It’s too late for my aunt but I hope it never happens to anyone else in my family. Efhkaristo poli!2
u/doker0It's the fat -> no it's sugar -> no it's sport -> no it's stress -> forget it, it's genes...   The Science.2
u/Starwaverraver[removed]1
u/GarifalliaPapaBest scientific research: [1] Optimal Cardiovascular Health in Type 2 Diabetes May Reduce Dementia Risk https://newsroom.heart.org/news/optimal-cardiovascular-health-among-people-with-type-2-diabetes-may-offset-dementia-risk [2] The Mediterranean Diet and Its Role in Reducing Cognitive Decline and Dementia Risk https://pubmed.ncbi.nlm.nih.gov/39797935/ [3] Vitamin D, Homocysteine, and Omega-3 Levels Associated With Reduced Dementia Risk https://foodforthebrain.org/good-omega-3-homocysteine-vitamin-d-status-cuts-the-risk-of-dementia-to-a-quarter/ [4] Lifelong Cognitive Reserve and Its Role in Prolonging Disability-Free Survival https://pmc.ncbi.nlm.nih.gov/articles/PMC10084126/ [5] Impact of Loneliness and Social Isolation on Cognitive Aging https://pmc.ncbi.nlm.nih.gov/articles/PMC10357115/ [6] Effects of Heavy Metal Exposure on Brain Health and Neurodegeneration https://pmc.ncbi.nlm.nih.gov/articles/PMC12625418/ [7] Effects of Intermittent Fasting on Cognitive Health and Brain Aging https://pmc.ncbi.nlm.nih.gov/articles/PMC10413426/ [8] Long-Term Exercise Training Improves Memory and Cognitive Function in Middle Age https://www.nature.com/articles/s41598-019-40040-8 [9] The Glymphatic System Clears Amyloid-β and Tau Proteins From the Human Brain https://www.nature.com/articles/s41467-026-68374-8 [10] Sauna Bathing and Its Potential Protective Effects Against Dementia https://pmc.ncbi.nlm.nih.gov/articles/PMC7560162/ [11] Aging Study Discussion on Cognitive Decline and Dementia Risk Factors https://academic.oup.com/ageing/article/46/2/245/2654230 [12] Study Results on Cognitive Aging and Dementia Risk Factors https://pmc.ncbi.nlm.nih.gov/articles/PMC10168460/ [13] Translating the Biology of Aging Into New Therapeutics for Alzheimer’s Disease (Senolytics) https://www.jpreventionalzheimer.com/7690-translating-the-biology-of-aging-into-new-therapeutics-for-alzheimers-disease-senolytics.html [14] Plasma Dilution Therapy Improves Cognition and Reduces Brain Aging Markers https://pmc.ncbi.nlm.nih.gov/articles/PMC8050203/ [15] Cyclic Overexpression of Yamanaka Factors in Neurons Reverses Age-Associated Brain Phenotypes https://pubmed.ncbi.nlm.nih.gov/38789561/ [16] Researchers Rejuvenate Brain Neurons Through Cellular Reprogramming https://web.ub.edu/en/web/actualitat/w/rejuvenate-brain-neurons [17] Sauna Bathing, Heat Shock Proteins, and Potential Reduction of Dementia Risk https://saunas.org/sauna-dementia-risk-hsp-hormesis/ [18] Young Plasma Rejuvenates Blood DNA Methylation Profiles Associated With Aging https://academic.oup.com/biomedgerontology/article/79/5/glae071/7618060 [19] Senolytic Therapies Targeting Aging Biology in Alzheimer’s Disease https://pmc.ncbi.nlm.nih.gov/articles/PMC11103249/
u/TappindatfannyLots of saturated fat to avoid Alzheimer’s-2
u/Cat_Daddy37You left out the importance of lithium, and also a warning against the phytotoxins found in many leafy greens that can actually contribute to pro-aging and neuro-degeneration effects. Consuming certain leafy greens can form reactive oxygen species in the body which is linked to aging and neuro-degenerative conditions. Many of the phytotoxins in them block essential mineral or vitamin absorption, can turn into neurotoxins in the body such as cyanide, can cause inflammation which damage organs slowly over time, contribute to kidney stones due to high oxalate and therefore UTI's (while UTI's are positively correlated to dementia risk). Leafy greens seem more detrimental to human health than helpful it seems since you can get all the benefits of leafy greens from other foods minus the toxins. Such as meat, dairy, or other fruits and vegetables. And lithium is like the #1 promising dementia supplement recently, especially for alzheimers because it inhibits GSK-3 beta enzyme, which reduces tau and amyloid buildup. And it also increases "brain-derived neurotrophic factor" levels, increasing neurogenesis and neuroplasticity.-10
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10r/tresslessProof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. P...noeyys1380%9773.8stem cell therapy2026-03-10
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u/Radiant-Community467Remindme! -1825 days132
u/1StationaryWandererOk so… when are we getting AMP-303 lol97
u/dorsei👀 William Rassman, MD, an Amplifica co-founder, adds, “The results observed in the frontal temporal region are particularly encouraging, as this area has traditionally been one of the most challenging to demonstrate a clinical response. AMP-303’s potential to stimulate hair regrowth in this region underscores its unique potential and sets it apart from existing therapies. Findings from this initial clinical study offers renewed hope for patients struggling with hair loss that have historically been resistant to treatment.”74
u/0zetoSo how does Ru58841 a topical anti androgen protect from androgenic alopecia then? No fr i get it, multiple pathways can be targeted but eh... androgens definitly are somewhat relevant39
u/oartistadoespetaculo5 years37
u/KamikazehogCan I get a TLDR for the TLDW? Jk thanks for sharing27
u/F0x_is_killReminder that Hair loss forums have posts from 2005 saying "just 5 more years" btw23
u/jeansarkozy1607yeah and the fact its an injection is even better no topical to apply and at least maintenance but i will be fully bald by the time this come out ....22
u/GRAND_PrepI'll wait for the haircafe video20
u/megaman2500Verteporfin activates trps1 after wounding, dr longaker talks about it in this video presentation at at around 18:30 timestamp https://youtu.be/CpfsAbOuOCY?si=Wp3aa2PMeaCTvlvw Furthermore, this paper by shamik mascharak et al Goes into it https://pubmed.ncbi.nlm.nih.gov/35077667/14
u/ItsToboLadsI'm getting flashbacks to brocolli boy13
u/The_Cabal_This guy again13
u/LWJ748A segment of the hair loss community reminds me of a segment in the fitness community. In fitness it's very well established what works. Yet you have a swath of people doing everything they can to avoid that while wondering why they don't get results. People seem to go out of their way to avoid anything DHT related. I started losing my hair in my early to mid 20s. I'm now in my 40s with a 20 year old hairline because of duta/min. Maybe something better will come along, but at present time you're losing gains avoiding what works.9
u/Jrlu92Let me guess, there’s a mouse out there looking like a young Rick James7
u/miyeetsGood research. I always had a problem with the "dht is the root cause crowd." To me it's quite ovioious dht is just a part of the equation of hairloss and of course, if you disturb an equation with a 5ar inhibitor, it helps, but it's not the cause.6
u/AppliedLazinessThey really did that guy dirty with the caption...5
u/TerryMiseryWhere did you read AMP-303 is osteopontin analog?3
u/TwistingSerpent93There is this study in which androgen sensitivity has been induced in mouse follicles, triggering miniaturization similar to that in MPB. I'd hypothesize that if you took two healthy follicles from a man's scalp, one in the "androgen sensitive zone" and the other taken from the base of the back of the head, and implanted both of them in the same spot (let's say the upper back), the follicle extracted from the androgen sensitive zone would display profound miniaturization in relation to the other.3
u/Quirky_Comfort_7083Dgaf its not available yet.3
u/Comfortable-Rock4349Remindme! -1823 days2
u/Zealousideal-Fox623they went after my niggas nose2
u/Own-Luck4169Measurable increase in hair count. From what they say is nothing wow at all yet you talk as if this is the real cause and is not, I can tell you 100%. Why? Is simple, the moment they will understand the real cause they will say: Hey we tried to fix this and the moment we did it, all hair grew back. Saying that PP405 won t work and this one will is kinda troll since this one doesn t have any outstanding results as you can read on their page. I think both will work but don t expect wow results.2
u/VolturmusThanks ChatGPT2
u/benshiro93Release date ?1
u/farcedsedRemindme! -3650 days1
u/Ok-Neighborhood4798If DHT is not the main cause of hairloss then why did it immediately stop after 2 weeks of me taking finasteride and slowly growing back now 9 months later?1
u/wonderboylsdI am not a professional in this field. Perhaps you are right. However, I fail to understand that if the effect of PP405 is extremely poor, why they have launched Phase III clinical trials and received such a substantial investment. Could it be that the purpose of this company is money - laundering? It won't be long before we obtain the results of the Phase II clinical trials. Let's wait and see. I hope you are wrong.1
u/jasko666Does this mean I can stop with Dutasteride?1
u/ROCKSTAR_LH_MENRemindme! -365 days1
u/Specialist-Escape300but what pp405 do is to directly trigger the follicle stem cell1
u/AloopOfLoopsAMP-303 is 15% regrowth. That is not so impressive. I mean i guess it is okay compared to minoxidil. We will have to see if more injections lead to more regrowth. If that it the case then it is interesting for real. Would be great of someone would inject some Osteopontin in there scalp: Buy it here freeze dried: https://www.sigmaaldrich.com/SE/en/product/sigma/o4264 Dissolve the powder in a sterile saline solution. Then dissolve down to maybe 2 ng/ml (just guessing and i want to guess very low for "safety") then inject in to scalp. The issue might be that real Osteopontin is a big molecule and might not diffuse very well. Where i assume AMP-303 is a smaller functional analog and not just pure Osteopontin. As that would make it better for injection and also make it patentable securing their money. Another issue is that large amounts of Osteopontin may be cancerogenic.1
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u/Odd_Sir_8705We have been 1 more year away for 10 years now….you know how long 5 more years away will be? RemindMe! -7500 days
u/TheHeftyAccountantI’ve been thinning leading up to and since swapping to Dutasteride about 1.8 years ago. I started PP405 8 months ago and had promising results for the first month but it’s since had no impact. Hoping this explains how my hair can continue thinning even though i’m on both a systemic and topical anti-androgen regime. edit: lol, i meant pyri, not pp405. what a gaffe-10
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11r/NooTopicsDid this come true?ps4roompromdfriends46980%38972.9stem cell therapy2026-03-09
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u/Party_Candidate7023yes, i am so sick of the FDA waging war on sunshine!151
u/HamHockShortDockWhat is their obsession with ivermectin and hydroxychloroquine?? How is this making them money?87
u/Virginia_HallI have not yet found my favorite psychedelics on Amazon.43
u/VkardashFirst off. He's the head of HHS and not the FDA. Does he have influence? Yes. But the FDA has its own commissioner, regulatory process, and Congressional oversight. And none of this shit he said ended up being true. Surprise to no one. The FDA still regulates everything he mentions in that tweet. Raw milk is still illegal in most states. No sweeping reform in psychedelics. Stem cell clinics are still highly regulated. None of these systems disappeared. It honestly sounds like he's just making stuff up. "War on vitamins"??? You can buy vitamins literally anywhere. 😂42
u/itswtfeverbMarijuana? ........Oh, I forgot the alcohol industry paid to nix it25
u/Ashamed-Status-9668In 2025 he laid off 3500 folks in the FDA and in total about 10,000 folks in the U.S. Department of Health and Human Services (HHS) which includes the FDA.22
u/Optimal-Hunt-3269Don't forget high colonics!13
u/vonbehren[deleted]12
u/sirsadalotHe did absolutely nothing. Similar to how Trump did the opposite of everything he promised. TL;DR? Nothing ever happens.10
u/pdublyPerhaps a better way to ask this question would be to decompose what he’s saying, and attempt to find evidence of any progress. Then perhaps extrapolate out… I feel many in this sub are missing the point, and being overly political. He is a political appointee, and probably misspoke somewhat. Disclaimer: I’m no cult member. :) To be fair, “supplements” are typically all thrown into one bucket by mainstream science and dismissed out of hand. What is generally said is that supplements are not effective. The truth is that there isn’t robust evidence to make such blanket statements. Which is to say that the studies haven’t been done which would ‘prove’ whether or not ‘supplements’ are effective in improving health. Not to mention that throwing all supplements into one bucket and making generalizations is completely disingenuous. Nonetheless, there is research on some specific supplements that show they either do or do not have an effect on human health in specific contexts. One off the top of my head is creatine. My point is that ‘supplements’ are typically dismissed out of hand by mainstream health professionals and scientists, many of which never learned about the topic in medical school and do not have studies that would to point to their conclusions in a meaningful way. Their statements are then typically interpreted (or explicitly said) as ‘they don’t work’, whereas the truth is that broadly there isn’t enough scientific research nor studies to say conclusively either way. So, if mainstream science is dismissive without evidence (ironic), they are lending credibility to that argument, while the truth is there isn’t enough data, evidence, science, research to make that conclusion. Essentially, they are stigmatizing the topic, which can have negative downstream effects of creating a general lack of interest in a topic that could in fact lead to positive outcomes from research into these substances, which happen to be largely unpatentable. “FDA’s war on sunshine” sounds absurd, but there is concern that sunscreen could block the bodies ability to create vitamin D. There is at least one study looking at this specifically. I don’t recall the results or robustness of the findings. You’re welcome to look that up on the NIH website. Anecdotally there is also some research out of Australia that looks at sunscreen usage rates and skin cancer rates over time (correlation does not equal causation). Again, you can go look that up yourself, the science is real. It is established that a majority of people in the U.S. have low levels of vitamin D, do not get enough in their diets, and it’s a health concern. Regarding peptides… There are recent changes which appear to be paving the way towards better standards and regulations to make peptides safer for end users by limiting fly by night sources, improving oversight of compounding pharmacies, and not penalizing doctors and end users. This is happening in realtime. The peptides user community crowdsourced testing of some of the research chem sources, and it’s a bit scary. I’d tentatively call all the above progress. What about the horsey paste? In the end, there may be some value in ivermectin use with covid, perhaps simply via some anti-inflammatory mechanism. I’m not an ideologue on this issue either way. I think being open minded and doing the science is the right path. We don’t have conclusive science (only clinical evidence) on whether it helps or not, and to what degree it is helpful or harmful. Again, it’s been politicized on both sides, and as a result we either miss the potential benefits or risk the potential harms. Who does benefit from the fighting and lack of science? It’s a fair question, but probably not for this sub. I’m not defending anyone here, just humbly attempting to make a more nuanced point that people tend to jump to conclusions without evidence, and in a sort of scientific-ish r/ where we’re sorta fringe anyway, we ought to be taking a more scientific and objective look at stuff like this. It’s not doing ourselves or anyone else any favors to continue to contribute to misunderstanding by politicizing topics and derailing objective science.10
u/OrganicBrilliant7995Regardless of whether you like RFK, the FDA is and has been the greatest obstacle to health progress. This is what most voters want, though. They'd rather have safety over reward and the risk that comes with it. If we have to have a few corrupt officials paid off by pharmaceutical companies, so be it.7
u/Cautious-Ad-9554If you want this to come true you have to support unions and establish a more realistic life/work balance for American workers. You also have try and do things like have employer based insurance refund gym memberships if you go. This admin is very anti worker. RFK’s goals are unattainable for the masses bc of who he works for.6
u/xiovelrachRFK is functionally braindead and has setback public health decades.6
u/irlostrichIf we’re being charitable, then maybe we could say his attitude contributed to the buzz we see about grey market peptide usage (eg the “chinese peptides” craze on twitter). I personally think this would have happened in any timeline with ozempic though. And I’m tempted to say that the state of affairs for the nootropics demographic in general has actually gotten worse during this administration due to tariffs making it harder for us to import from india and china.5
u/Full-Shelter-7191It’s based of anti-scientific rhetoric and the false premise that somehow the FDA is trying to surpress your access sunshine, vitamins and exercise5
u/painalpeggyAre people healthier yet?5
u/Ok_Refrigerator9461We’re all going to die.4
u/MisterallrounderRFK is against nature..he is trying to ban Kratom yet here he is saying that he is FOR nature...it's sickening3
u/Noblez17I'm Down for psychedelics at least 🤷🤷‍♂️3
u/Jwbst32Glyphosate for all !!! 😂😂😂3
u/Actual_Musician_4157Lmao nothing changed3
u/nonlinear_nycWe got… roundup in our food supply.3
u/[deleted]Funny that the Trump admin is taking all that pharma money and they’re making record profits, again3
u/Automatic_Opposite17Says the heroin addict, coke-head brainworm guy.3
u/LessMention7652Why did he forget methylene blue and MMS?2
u/SoggyGrayDuckLikes peptides but against 7oh. Someone just needs to get him to sit down with the 7oh hope alliance. He should understand the benefit. I think he was one that used benzos or liberum from a doctor for several years after stopping street drug use. It's something you'll see is actually quite common in older AA stories. It's like a 5 year period of something you can use to take the edge off but won't destroy your life at the same time (historically controlled by the number of pills in prescription) if you mess up and have a bad day.2
u/No_Opportunity1934Bro hasn’t even gotten red40 off of shelves though?2
u/popcorn-triviaHasn’t come true for peptides. I think more and more sites get shutdown (b/c semaglutide peptide cuts into Ozempic profit, etc).2
u/BGMilanHere come the reddit scientists2
u/No_One_1617For the rich it has always been true2
u/SillySpoofGood thing FDA stopped suppressing sunshine and exercise. /s2
u/Inevitable-Cherry598But we're using toxic pesticides proven to cause cancer because Trump loves Monsanto.2
u/xbt_The peptide part somewhat improved very recently, a list of them recently got approved to be compounded in the US. Not sure about any of the rest.1
u/Traditional_Air_6867“Post Meridiem”? Woah, dudes really accessing 100% power here…1
u/cs_legend_93Make dmt legal 100% and then I'll believe you.1
u/surstrommingsexNew foundation of RC scene since NL ban? 🥲🤣🤣1
u/SamPDougWhat a good-looking question! Lol, no. And based on what I’ve heard from RFK jr lately, what little change there will be is going to be very slow.1
u/Leading_Matter_1168Oh thank god! I’m so ready for the drugs1
u/hoteppeterIt’s in progress1
u/IncandescentSplashAs someone who has benefited enormously from psychedelics, I hate seeing the thing that helped me become associated with this completely unqualified Trump grifter and named in the same sentence as ivermectin and hydroxychloroquine.1
u/michaelmhughesWell, the moron is responsible for the rise in measles, for one. He’s a dangerous lunatic whose face looks like an old shoe.1
u/Ok-Parfait-9856No, the current administration has shut down peptide vendors. They do the opposite of everything they say.1
u/Conscious-Comment-66Sunshine and milk came true!1
u/ScaryLetterhead8094But also the hemp bill is making CBD much less accessible. Right? So what’s up1
u/Olga2757He forgot snorting off of toilet seats.1
u/ketchupisfruitjamhe had me at the first half I'm not going to lie. broke clock is right twice a day1
u/DrbilluptownHe has such vast medical knowledge. /s1
u/fleetzeI love how he's mixing in the BS like. Sunshine, bloodletting, exercise, flat earthery, get good sleep, drink mercury.1
u/SCHawkTakeFlightNot yet, hoping we dont go back to non evidence based medicine. Don't have to prove a therapy works before consumers spend money on it or at a minimum won't hurt you. Also, at one point I am betting ivermectin, hydroxychloriquine and hyperbaric devices were patented...thats generally how new innovative tech works. It gets patented to secure profit for x time. After x time anyone can make it. Otherwise, there is disincentive to make anything new if someone can copy it right away and sell it cheaper because they dont have to recoup all that development cost.1
u/DizzyMeatball1791It’s crazy that a man in recovery wants to promote psychedelics.1
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12r/ValueInvestingAvoiding dumb mistakes might be more important than following good rules in inve...RawDogStudios1340%4671.2stem cell therapy2026-03-15
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u/ColForbinClimbsCapital preservation is key29
u/CompoundQuietlyGreat thought. You've hit the classic Munger philosophy - think about what would cause failure and then do the exact opposite. In his words: "It is remarkable how much long-term advantage people like us have gotten by trying to be consistently not stupid, instead of trying to be very intelligent"12
u/DaveFoSrsDon't invest in a business you don't understand. Don't "figure out" what a company does from its shills on WSB and Stocktwits--they have a vested interest in duping people. Avoid small cap stocks, especially if the above it true. Don't invest pre-revenue or pre-cash flow positive Source: I was a moron in my 20s9
u/mrmrmrjMinimize losses. Sell losers quickly. You can always buy them back. There seems to be a psychological resistance to selling a stock after owning it for only a month or two if it is down. I don't get this.4
u/Q16QGreat to see someone think about fundamentals. You have a better chance of succeding.2
u/Few-Perspective4430Good point. In investing, sometimes the biggest wins come from simply avoiding bad decisions. Many people chase hype without understanding the business or checking the fundamentals. Sticking to what you understand and avoiding obvious red flags can save a lot of money in the long run.2
u/Hamzehaq7totally get what you're saying. it's wild how many people jump into stuff without really digging into the basics. like, sure, AI is hot, but if you're looking at companies like Oracle with that kind of debt, maybe take a step back? lol. sometimes it feels like folks want the thrill of investing without the actual work. it's all about balancing enthusiasm with common sense, imo. avoiding those super obvious red flags can save you a lot of pain later. what’s your take on the whole AI hype right now? seems like everyone's trying to chase that next big thing.2
u/CherryRoutine9397Avoiding dumb mistakes honestly does more for your money than trying to find the perfect strategy. Most people lose because they chase hype stocks, overtrade, or copy random portfolios they saw online. Keeping things simple and actually understanding what you own already puts you ahead of most investors. I write about stuff like this sometimes, link is on my profile if anyone’s curious.2
u/Dependent-Panic-9457I agree with the point about debt. I am nonetheless up to my neck in Jadestone Energy. Actually: above my neck.1
u/BCECVEgive us more. thx1
u/CalendarNo6655I actually genuinely enjoy reading and learning about these companies. I think big pharma, nvidia, or biotech is really interesting though investment wise they are not ideal. I think there are some 10/10 companies but they rarely go on sale. Unfortunately the market prices them too well1
u/jay_0804Avoid obvious mistakes first. Examples: Snapchat never profitable, Tesla P/E 363, Oracle high debt. My rules: long profitability, decent ROIC, understand what you own, low debt, real moat. Avoid dumb errors before chasing perfect setups.1
u/One-Event6199Someone on this subreddit who actually has useful thoughts/insights. This is so spot on. This is Buffett/Munger/Lynch in a nutshell.1
u/Lost_Percentage_5663Most ppl are IQ100. But they think they are IQ110. All tragedies happen with it.1
u/AInotGLesson: If it is being discussed publicly, probably it is already overpriced-3
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13r/InterstellarKineticsBREAKING: Scientists Just Built Living Bodyguards for Insulin Cells That Could C...InterstellarKinetics4720%870.9stem cell therapy2026-03-03
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u/einstein2025And its not going to make it in market. They don’t want you to get well just get hooked on pills5
u/InterstellarKineticsThe immunosuppressive drug problem is the one that most people outside of transplant medicine do not fully appreciate. After an organ or cell transplant, the recipient's immune system has to be chemically suppressed for the rest of their life to prevent rejection. Those drugs work by broadly dampening immune activity, which means the patient is permanently more vulnerable to infections, cancers, and every other threat the immune system normally handles. For a 40 year old receiving a kidney transplant, the risk-benefit calculation is often clearly in favor of the transplant. For a child diagnosed with type 1 diabetes at age 8, a lifetime of immunosuppression starting in childhood is a genuinely difficult tradeoff. What the MUSC team built is a way to get tissue-specific immune tolerance without systemic immunosuppression. The engineered Tregs are not broadly suppressing the immune system. They are precisely positioned at the transplanted beta cells using the CAR receptor and their job is specifically to protect those cells from immune attack. The immune system continues to function normally everywhere else in the body. That specificity is the engineering achievement that changes the risk calculus entirely. The stem cell manufacturing side is equally important to understand at scale. Current islet transplants require beta cells from three to four organ donors per patient. There are not enough donors in the world to treat 1.5 million Americans with T1D, let alone the global population of approximately 8.4 million people with the disease. Lab grown beta cells that can be manufactured, quality-controlled, frozen, and shipped like any other pharmaceutical completely bypass that donor shortage. If the one-month durability in mouse models translates to multi-year durability in humans, this framework could be the actual end of daily insulin injections for the majority of people living with type 1 diabetes today. What other autoimmune conditions do you think this kind of targeted Treg bodyguard approach could be applied to next?4
u/Difficult-Till5031Hopefully this makes it out of trials. But I fear like a lot of other treatments it will be shelved or unaffordable.2
u/Broad-Term1872X: Doubt1
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14r/MultipleSclerosisNo more DMT after agressive evolutionRemyMajd1120%4670.5stem cell therapy2026-03-07
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u/youshouldseemeonpainThere was a new drug specifically for PPMS and SPMS that was supposed to get approved last December. The FDA denied it, but it may still come out later. It’s called Tolibrutinib, and I’m hoping they can jump through whatever hoops are required to get it on the market soon. I’m sorry for your situation. This disease sucks, specially PPMS.57
u/FragrantQuail5559I had a good friend with MS that was in a wheelchair by his mid 30s. I used to hang out with him and play monopoly and just talk. When I was diagnosed several years later I didn’t have the heart to tell him. He has a positive spirit. Stay positive. Life doesn’t end it just changes. Look into programs that can help you. If your doctors office has a social worker ask to speak with them to find out about assistance.52
u/jmoroni89Fuck. I'm right there with you brother. 37m. Been on Ocrevus for 4yrs, PT for 3. Nothing is helping. I've been told I should be in a wheelchair. I fall all of the time. My daily regimen, baclofen 30mg 4x a day, 10mg edible 2-4x a day. The edible helps my body relax more than just the baclofen. When I do too much (normal shit for regular people) my index and middle fingers on my right hand spasm and I can't bend them. They eventually go back to normal. We're too young for this shit man. I hope you find something that helps you and I hope you have someone to talk to about it all. Stay strong brother. FUCK MS41
u/LaurenlondonerHave you had a recent MRI? I’m sorry that is happening to you, MS sucks, and it’s scary😩😩19
u/ThermostatMcGeeHave you discussed Briumvi, Lemtrada, or Mavenclad?? I'm shocked she just wants to stop at Ocrevus. I've gone from Tysabri to Ocrevus to Briumvi. If needed, Mavenclad or Lemtrada are next up in my doctor's plan. Your rapid progression sounds like a reason for more intervention, not less.16
u/BucktoothWookieeAfter I “failed” a few meds, the last being Ocrevus, I did Lemtrada. Have you discussed that option? It’s “big guns” but finally stable and in a remission. And no ongoing infusions or anything anymore.13
u/SpookynashMS has destroyed too much of my body to even begin listing. Zero balance, legs declining significantly (below 30% function), spasticity, stiff back muscles (crazy painful). Mobility shot, nerve pain off the scale on a regular basis. It easier to tell you what doesn’t hurt, and what works properly. Crushing chest pain, not heart related. I’m only 53. Had to give up my job of computer programmer when I started 19 years old. NOBODY SHOULD HAVE TO LIVE LIKE THIS. You are not alone!! 🙏💛8
u/JooleyceeAHSCT available where you live? 38 is too young to stop treatment.6
u/BobbybezoYes, I'm in the same case, wheelchair and all, PPMS is quite something, I got diagnosed at 49 . Know that I'm with you!6
u/SpotTheDoggoI stopped ocrevus after 3-4 years recently, too. In my case, it was still effective, but I developed a very mild chronic lung infection. I cough up the nastiest shit. Sorry to hear about your struggles, buddy. :(6
u/Daurth_ZombieI’m most likely on my way. We should all paint our chairs SHINY AND CHROME!! WE SHALL RIDE ETERNAL THROUGH THE GATES OF VALHALLA!! My girlfriend is against this. BUT I WILL NOT BE DENIED!!!5
u/JustlookingfromSoCalI am more or less in the same situation. But I am a lot older than you. In addition to PT and Baclofen, I do find that Dalfampridine (Generic Ampyra) does help me with standing, balance and the steps I need to make when walker assisted transferring to and from bed or wheelchair and in and out of my bathroom which is too narrow for my chair. At your age, I wonder if trying a different DMT makes sense though. Are you able to get a second opinion from another Neuro with an MS specialty?4
u/Maleficent_Fun_7622talked with your neurologist about stem cell therapy?4
u/PK5002I have SPMS and was on Ocrevus for 2 1/2 years. My neurologist recently switched me to Tysabri because Ocrevus wasn't helping. MS just kept progressing while I was on Ocrevus.3
u/Jillo616I would personally look into another opinion. It’s quite possible meds will no longer help you, but damn. I wouldn’t want to give up. I’m sorry for your situation and I hope you find some relief.3
u/Tall-Pianist-935Get that new DMT And get some curcumin to help it along. Good Luck.3
u/Der_BingomannHello. I'm 44 years old. I was diagnosed with PPMS at the end of 2024. I can barely walk anymore. After just one year, I had a 60% disability rating and am already retired because I can no longer work. I need help with everything in my daily life. Ocrevus didn't work for me; on the contrary, I never felt worse, and all my symptoms worsened. I started making videos about it on YouTube. I'm taking baclofen and cannabis. I've stopped taking Ocrevus. There's nothing left to do but accept my fate...3
u/Ok-Elderberry7087Yes! Look for CAR-T. Life changing!2
u/dontgiveah00tI wish I had advice for the MS, mine doesn’t have me in a chair (yet) but it’s been 1.5 years and still struggle to walk a mile a day (spread out). However for mental heath Spravato really helped me and low dose naltrexone for pain and mood.2
u/buderfwyDon't give up! You're important and meant to be here. I love you and am glad we share the same earth at the same time. Keep fighting2
u/Far_Ebb_7477Yup. Full time wheelchair user now. Diagnosis PPMS, not taking any ms drugs anymore. Just baclofen and fampyra. Fampyra has helped give me slightly more strength. I think it's called ampyra in the states. I'm in Canada. The meds make the signals jump down the nerves (instead of going down a straight line) with the hopes of skipping a lesion. I mean I can't walk, but when I don't take the meds I have a harder time transferring to the toilet or holding utensils. With the meds it's easier. It's expensive though I was a photographer and an artist. And now , I don't know what I am2
u/Wooden-Use-2640I have primary progressive multiple sclerosis and my neurologist tried telling me the same thing.2
u/Electronic-Mammoth19Sending prayers man. 38m here too although early in my journey as I was diagnosed last year. Just did my first infusion of BRIUMVI earlier this week and been on a strict diet since the last relapse. It’s honestly been happening for years, so I’m happy to have an explanation. I read these forums but rarely comment, but your story touched me and I wanted to say you are in my thoughts and prayers.2
u/Ill_Algae_5369I'm so sorry. I don't know where you are but maybe there are trials you can get in on? Even if for movement and spacicity not the lesion activity itself?1
u/Murky_Bird_2695I’ve been dealing with this since seventeen unfortunately but I’m now bedridden and wheelchair bound. 31 now. Definitely sucks1
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15r/immortalistsMitochondrial Dysfunction is a major hallmark of aging. By repairing Mitochondri...GarifalliaPapa1940%2070.1stem cell therapy2026-03-23
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u/GarifalliaPapaI am writing this for the other scientists who are interested in the aging science (advanced mechanisms): Mitochondria function is a central regulator of aging because they integrate energy production, redox balance, apoptosis, and immune signaling into a single system. Their primary role in ATP generation through oxidative phosphorylation links directly to cellular repair capacity, while their production of reactive oxygen species (ROS) acts both as a signaling mechanism and a source of damage. In parallel, mitochondria control programmed cell death via cytochrome c release and contribute to innate immunity when mitochondrial DNA (mtDNA) leaks into the cytosol and activates danger pathways. When mitochondrial quality declines, these systems become dysregulated simultaneously, making mitochondrial dysfunction both a driver and amplifier of aging. With age, mitochondria accumulate a set of characteristic defects that impair their function. Mutations in mtDNA disrupt electron transport chain (ETC) proteins, reducing efficiency and increasing electron leakage. This leads to elevated ROS production, which damages lipids, proteins, and nucleic acids. At the same time, mitochondrial dynamics become imbalanced: fusion processes (regulated by MFN1/2 and OPA1) decline, while excessive fission (linked to DRP1 activity) fragments the network. Compounding this, mitophagy (the process that removes damaged mitochondria) becomes inefficient, allowing dysfunctional organelles to accumulate and dominate the cellular environment. These defects form a self-reinforcing feedback loop that accelerates aging. Initial mitochondrial damage reduces ETC efficiency, increasing ROS generation. ROS then damages mtDNA and mitochondrial membranes further, worsening dysfunction. Impaired mitophagy prevents the removal of these damaged units, while the release of mtDNA into the cytoplasm activates innate immune pathways such as cGAS–STING, driving chronic inflammation. This inflammatory state feeds back into mitochondrial damage, linking mitochondrial decline tightly with systemic inflammaging and cellular senescence. As mitochondrial performance deteriorates, cells experience a bioenergetic crisis. ATP production drops, impairing essential processes such as ion transport, protein synthesis, and DNA repair. The increased AMP/ATP ratio chronically activates AMPK as a compensatory mechanism, but this cannot fully restore energy balance. Cells increasingly rely on glycolysis, a less efficient pathway, creating a pseudo-Warburg metabolic state even outside cancer. At the organism level, this manifests as sarcopenia, reduced brain energy metabolism contributing to neurodegeneration, and diminished functional reserve across organs. Mitochondria also exert direct control over nuclear genome stability and epigenetic regulation. Excess ROS induces nuclear DNA damage, while declining NAD⁺ levels impair the activity of key repair enzymes such as PARP1 and sirtuins (SIRT1, SIRT6). Additionally, mitochondrial metabolites act as cofactors for epigenetic enzymes: acetyl-CoA drives histone acetylation, α-ketoglutarate regulates DNA demethylation, and NAD⁺ supports deacetylation. When mitochondrial metabolism is disrupted, these epigenetic processes become unstable, leading to epigenetic drift, altered gene expression, and reduced cellular resilience. To maintain mitochondrial integrity, cells rely on a coordinated quality control system. Mitochondrial biogenesis, driven by PGC-1α, AMPK, and SIRT1, generates new organelles. Mitophagy, regulated by the PINK1/Parkin pathway, selectively removes damaged mitochondria. Meanwhile, dynamic fusion and fission processes allow mitochondria to exchange contents and isolate defective components. Aging disrupts all three arms: biogenesis declines, mitophagy becomes inefficient, and dynamics lose balance, resulting in a network increasingly composed of dysfunctional mitochondria. Lifestyle interventions remain the most robust methods for improving mitochondrial function in humans because they directly target these quality control pathways. Exercise activates AMPK and PGC-1α, stimulating mitochondrial biogenesis and improving respiratory efficiency. Fasting and caloric restriction increase NAD⁺ levels, activating sirtuins and enhancing both autophagy and mitophagy while reducing ROS production. Hormetic stressors such as heat and cold exposure induce protective pathways, including heat shock proteins and FOXO3, which enhance mitochondrial resilience. Sleep and circadian alignment further regulate mitochondrial gene expression and oxidative stress cycles, maintaining temporal coordination of repair processes. Nutritional and pharmacological compounds can support mitochondrial function, although their effects are generally modulatory. NAD⁺ precursors such as NMN and NR restore intracellular NAD⁺ pools, enhancing sirtuin activity and DNA repair. CoQ10 supports electron transport within the ETC, while alpha-lipoic aci9
u/GarifalliaPapaBest scientific research: [1] Mitochondrial Dysfunction as a Central Hallmark and Driver of Aging https://www.tandfonline.com/doi/full/10.1080/28347056.2025.2560191 [2] Mitochondria as a Target for Rejuvenation and Anti-Aging Therapies https://pmc.ncbi.nlm.nih.gov/articles/PMC10917551/ [3] Role of Mitochondria in Oxidative Stress, Inflammation, and Aging https://www.nature.com/articles/s41392-025-02253-4 [4] Novel Mitochondrial Mechanisms Underlying Anti-Aging and Longevity https://www.news-medical.net/news/20251210/Study-elucidates-novel-mitochondrial-mechanisms-underlying-anti-aging-and-longevity.aspx [5] Urolithin A Supplementation Improves Muscle Endurance and Mitochondrial Function https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788244 [6] Clinical Evidence on Urolithin A and Mitochondrial Health in Humans https://pubmed.ncbi.nlm.nih.gov/35050355/ [7] Mechanisms of Red Light Therapy and Its Effects on Mitochondrial Function https://optimalhealth.co/resources/red-light-therapy/science [8] Photon–Cell Interaction Mechanisms in Low-Level Light Therapy and Mitochondria https://www.liebertpub.com/doi/10.1089/photob.2018.4606 [9] Mitochondrial Donation Therapy: Clinical Advances and Birth Outcomes https://www.ncl.ac.uk/press/articles/latest/2025/07/mitochondrialdonationtreatment/6
u/EnclicidusGreat read. Our mitochondria are such a vital factor in so many facets of life. Looking more into and loving it. I’d like to add that last year I was trying to get a low body fat % and was doing intermittent fasting (18 hours) + the keto diet. While people did mention I looked lean and kinda sickly (lol), I had never felt so great in my 32 years of life. It was a hassle restricting carbs to under 30g while also caloric restricting myself, but the mental clarity, energy, and feeling so energized/healthy was unlike anything else for me. It was a sort of high I’d like to recreate but I’m unsure of if it was one or the combo. Will be trying it again this year.5
u/Pale-Stranger-9743Would methylene blue be a good tool to help with this?3
u/princesspoolExcellent work, new stuff here for me to dig into- thank you2
u/mdeeebeee-101Do nitric oxide powders used for gym pump vascularity hinder mitochondria ?2
u/YonKro22Is that why standing in front of a fire feels so good and is good for you I think it's got to be way better than standing in front of an artificial infrared light for one thing we grew up as a species doing just that2
u/Ill_Mousse_4240Another fascinating read! Really hope such research garners more attention. Powerful individuals like Musk and Bezos are trying to outdo each other in outer space. Individuals who, like us, exist in today’s world of limited lifespans. Each year that goes by affects them as irrevocably as everyone else. Unlike everyone else, they have the resources for effecting meaningful change. Yet, perhaps not realizing this, they continue focusing elsewhere. Like mayflies obsessed with sequoias2
u/Rude-Dealer9188Parasite Eve taught me this... but thank you 😊2
u/smart-monkey-orgFor now I'm sticking with exercise, fasting and GlyNac.1
u/Tasty-Windowwas just thinking about this1
u/ProprietorSooo…. Do some Wim Hoff and charge the mitochondria?1
u/kojefI don’t hear much about hydergine these days when reading about improving mitochondrial function. Why is that?1
u/Syn-thIs there a tldr?1
u/[deleted]Redact cleaned up all of my comments. Bulk deletion and editing is a feature supported to make sure that AI scrapers can't access my data for training. cobweb fade smart spoon hat work deliver juggle boast longing
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16r/exjwNew Cancer and Autoimmune Therapies Available that were Previously Off Limits fo...Slow_Watch_3730970%4469.7stem cell therapy2026-03-25
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u/Darby_5419And of course PIMI's are waiting for "clarification" from the GB overlords, to ensure they have permission to save their own lives in these private health matters....30
u/RhiboflavinImagine what it must feel like, to have a sick helpless family member slowly dwindling in front of you while you frantically search for any answer in watchtower garbage. By the time you find the answer is no. Your family member is 'moving on' and you wasted the few precious days you had with your loved one, all because 'men' decided on what the light says in this current decade. Disgusting.15
u/Diligent-Swimmer1966I work in dentistry. We have a procedure we call PRF or platelet rich fibrin where we draw blood, spin up a clot and use it in the socket when we do extractions on high risk or immunocompromised patients to help them heal faster or improve the overall prognosis. Witnesses adamantly have refused this proven therapy and some diabetic patients took months to heal up instead of weeks. I'm curious if those same people will have a different perspective when I see them again.13
u/Short-Complex-2410It pisses me off that people have lost their lives due to GB overreach. Recently a new woman in my parents congregation was diagnosed with cancer, I'm grateful she might be able to receive real treatment now. It seems like all lives lost before were in vain. Why didn't this "correction" come sooner? They will never ask.10
u/Pale-Cod3749Wow. Thanks for this and it absolutely should be its own post, if not pinned. It shows all the treatment options that were forgone by unaware, uneducated, obedient JWs facing death or excruciating pain or a longterm terminal illness. They thought they were obeying Jehovah’s explicit command, only because the GB forced them to obey and forbidden to research anything non on the JW dot con site. And if this is all about not disrespecting and wasting/improperly throwing out blood, if they’re saying they can remove their blood from their body and store it in bags in a blood bank, in advance of their own surgery, but don’t end up needing it… What about all the JW blood that’s not able to be used by anyone, according to the GB’s un-thought out new “exception”? With them adding in their own legally-protective, “blame-shifting” clause of “according to your own conscience” and a lowly, devout, obedient JW realizes that they did this thing that’s kinda unclear whether it’s ok with Jehovah, maybe their conscience will gnaw at them for having ended up “wasting blood” instead of just trusting in Jehovah (like those martyred children sacrificed for their Awake! cover were forced to)? It’s all such obvious bullshit. I hope they’re lurking in here and getting the message loud and clear that they need to just drop it all and not do this parsing out “spiritual food at the right time” or on Jehovah’s timing and just do the right thing and stop it. Now. Today. Pfft.9
u/Ancient_Team_7007This is where that statement — “the list of treatment options continues to grow” — really changes meaning. They’re not talking about relaxing the ban on blood transfusions. That part hasn’t changed. What they are doing is widening the category of what counts as “acceptable” by quietly absorbing newer medical techniques into the framework. So instead of saying “transfusion,” they avoid that word instead saying "give back", focusing on alternatives — many of which, in practice, overlap with what people would traditionally associate with transfusion-related care. It’s a linguistic and doctrinal balancing act: Keep the core prohibition intact Acknowledge modern medicine is evolving Reframe newer therapies as individual conscience decisions So the headline stays the same, but the application becomes more flexible over time. That’s why the wording matters so much(they say "clarification" instead of "change"). It’s not a change in doctrine — it’s an expansion of what can exist around the doctrine without appearing to contradict it. Mind blown!!9
u/ExWitSurvivorAnd all of the hundreds of JW’s who refused these treatments…who would possibly be alive today!!!5
u/goddess_dixthanks for sharing this information. for those of us completely uneducated in this area (i.e. me) i was wondering about this specific thing what treatments it opens up for people4
u/BolognaMorrisIVI'd caution against celebrating just yet. From what I'm reading, therapies like CAR-T or Stem Cell transplants still require donor blood and platelets to keep the patient alive during the recovery phase. While witnesses can now store red blood cells for up to 42 days, the platelets only last 5 to 7 days. It's apparently not possible to bank a month's worth of platelets, so they will inevitably run out during the recovery phase and die without donor transfusions. We really need somebody with actual medical expertise to go over all of this before we start popping the champagne.2
u/brooklyn_bethelI get what you mean, but it only affects countries which offer healthcare for free, so you don't have to do anything to get it. Otherwise if getting a therapy involves any action or money, Jehovah's witnesses are never going to apply for it. The cults teaches them to be useless penniless slobs. The cult teaches them to never care for their health or for themselves in general. The cult teaches and desperately wants them to be poor, uneducated, lazy and dumb. The cult brainwashes them into thinking they are going to live forever after death, so they don't take care of themselves and die from any smallest illness. It's ridiculous how destructive and evil the Watchtower cult is.2
u/EginmundisGreat post, useful research 🙏 thx2
u/Firm-Instance5489Pimo here, I had a family member that was very close to me die several months ago bc their lymphoma came back. They would’ve had access to much better options for treating relapsed lymphoma if weren’t for the GB. I had to watch them suffer due to ineffective treatments for years, when they could’ve had access to treatments that are clinically proven to be much better and have very high success rates. Clarification my ass, it isn’t clarification when it was pretty damn clear the org was against these treatments previously. How dare the GB not acknowledge any of the lives they negatively affected with this doctrine. I absolutely despise them.2
u/ClosetedIntellectualThat's pretty cool, actually. I didn't realize that all of those therapies use your blood.1
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17r/multiplemyelomaTen years agoHighyet1080%2768.6stem cell therapy2026-03-30
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u/per1sherWaking up is good! One day at a time. Thanks for posting this. I was diagnosed with smouldering MM in 2012 and have two transplants behind me. Feel pretty good right now and am very grateful.12
u/LonelyChampionship17Seven years for me. Still on maintenance but I work full time and have a good life. The gratitude does not fade.11
u/LeaStringPowerful telling and so happy you are here to write it. Ten years from back then on dex and one other drug only…you really beat the odds on SOC back then. I’m sorry you are in pain however. I hope you get reprieves from it with the help of palliative care. But to have no signs of disease now and off treatment for three years is something to be thankful for and celebrate. Taking wins when you can. I read your post to my guy, who like you was stage 3 with bone damage at diagnosis. He found it very interesting and hopeful. Back then when he asked, ten years was a good estimate for him. He’s now at almost 4. We’re hopeful for many more beyond the ten and feel good of his chances with advances in MM research and treatment. He was in extreme pain at diagnosis with several collapsed vertebrae, underwent ASCT, and still on treatment. Fortunately he feels good and without pain. Guess we never know what tomorrow brings but tomorrow does hold hope for better. Thank you for sharing your anniversary with us and we both wish you another ten at least. It’s encouraging to hear more stories of people living longer and longer lives.11
u/iNap2MuchAmen brother! Fellow MM patient here, bone marrow transplant last November and now recovering steadily. Glad for your recovery results. Hoping mine are the same.10
u/L31121Thank you for your story. I can only hope to make it at least that long. I'm going on 2 years since being diagnosed at stage 3 also.8
u/BrokenEffexThank you for posting this.  I’m 1 month post-BMT and 6 months post posterior spinal fusion from T9 to L1 with a corpectomy device at T11. I deal with pain every day, usually around a 7–8 out of 10. Right now, it’s my biggest source of anxiety. I’m 37, and it feels like the rest of my life may be heading toward pain management, which honestly scares the hell out of me. Your take makes it seem a little less severe than the picture my mind has been painting, so again, thank you.8
u/DeciduousEmuThanks for sharing I think I'm one of the fortunate few where they diagnosed me very early before I had any CRAB symptoms. Unfortunately my MM is considered high risk due to TP53 deletion from the genetic analysis. Hopefully I can get as many years as you.6
u/Fantastic_Fly_6434Thanks for your hopeful post. It means 10 years and beyond is doable for all of us. If you don't mind me asking, where is the pain coming from?. Bless you.4
u/Icy-Town-53559 years for me as of 4/7/17. I don't focus on it, and I think this is why I'm still here. Hugs to you all xox4
u/ShadowBard0962Thank you for sharing your story. 🫂🫂 Going on 4 years for me. Like you, I an in pain everyday all day, on Revlimid, but the cancer is in “deep remission”. I just saw my oncologist this past Thursday and he said I good stop the meds pending a negative bone marrow biopsy! So, wish me luck.3
u/Mommie62Good for you. I have chronic pain and a resource that helped me is an app called curable. They also have a Facebook group. Pain is a fun y thing despite things being repaired or healed the pain can persist but with the help of curable you can work in breaking down the established pain pathways . I wish you luck. My hubby has mm. He was low risk. Nearly 4 yrs post transplant and still on treatment. Doing well other than all his arthritis decking his joints. Awaiting shoulder replacement and had brutal foot surgery 5 mos ago3
u/WerewolfBarMitzvah09Thanks so much for your sharing your story. You're very strong. This gives me hope for my family member with MM.3
u/tofuraisinThank you for your post and I am so happy that you are cancer free!3
u/BB5erMy wife is almost 17 years post-transplant. Even off the Rev for a few months, here and there, the pain is more than it used to be. Like you, she works through it. Thanks for sharing your story.3
u/Myeloma-Fighter10 years is a milestone. I like seeing posts like this. It gives people like me hope. If you don't mind me asking, how old are you?3
u/AltruisticAccount909How are you able to be off maintenance therapy?2
u/Sad_Secret8253Thanks for sharing your story! sending lots of love and healing energy your way for the rest of your incredible journey 🙌🏻2
u/Sorcia_LawsonI had a very similar diagnosis story - broken clavicle, stage 3. I'm at 7½ years. But, my treatment ended up more complicated with more broken bones and other complications. The chronic and long-term pain sucks. But, similarly I'm appreciating still being here. Things with MM can change on a dime. For a while, I wasn't sure I'd make it to year 3 let alone year 7!2
u/Redneck-AstronomerI appreciate your post, as it gives me insight into my fight. Diagnosed over a year and half ago (MM IgD lambda, an unusual one), started Griffin induction right away and had ASCT four months into the treatment. It's been a year and three months since the stem cell transplant and am currently in the maintenance chemo with only Velcade. Pain is there, but I have a good palliative care physician as well. Wishing you all the best in the path ahead you.2
u/Mantisman51I was told it was a ASCT or palliative care. I couldn't wait to get the ASCT started. I'm glad you're doing well.1
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18r/immortalistsHyperbaric Oxygen Therapy (HBOT) significantly increases lifespan. Hyperbaric Ox...GarifalliaPapa960%3368.6stem cell therapy2026-03-04
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u/TheWatch83The time and cost are tough to swallow unless you are rolling in it and can have a hard HBOT unit in your house. Ive been tempted to do a 30 day therapy every day but its hard to spend an hour plus travel time back and forth to do it. Maybe sometime the planets will align and it will be close.16
u/Mission_Bullfrog3294Your comments make it sound like only three months of therapy is needed. Is that total? with no repetition schedule?6
u/Silky_MeatWhat is the investment needed to do this at a clinic versus buying the equipment for home use?3
u/ExerciseDear633Is this safe for patient stage 4 cancer?2
u/AllstarGERI have a chamber in Siegen, Germany If anyone is interested...2
u/Mission_Bullfrog329490 minutes at 2 atm 5 days a week! doesn’t that come with significant risk to your hearing? Anything more you can do than yawning and popping?2
u/JonaEnyaI already spoke about this days ago, Im doing this on myself already! I have a stack that will take us to 140 years, now...1
u/Cascadeflyer61I’m wondering if diving my rebreather gives me some of the same benefits? I breathe pure oxygen under pressure, although at deeper depths we mix air with the O2 to keep the O2 under 1.4 partial pressure to avoid oxygen toxicity. So it may have some similar benefits.1
u/LikeMrFantasticCool story, any cost effective methods?1
u/Phillip_CharlesIt didn’t extend Michael Jackson’s life1
u/[deleted]It's all fun and games until someone's autistic child burns to death.1
u/GarifalliaPapaBest scientific research: [1] Hyperbaric Oxygen Therapy Increases Telomere Length and Decreases Immunosenescence in Humans – PMC https://pmc.ncbi.nlm.nih.gov/articles/PMC7746357/ [2] Hyperbaric Oxygen Therapy Increases Telomere Length and Reduces Senescent Cells – Aging-US https://www.aging-us.com/article/202188/text [3] Tel Aviv University Study Reports HBOT Reverses Biological Aging Markers https://www.eurekalert.org/news-releases/667837 [4] HBOT Prolongs Telomeres and Reduces Immunosenescence (Prospective Study Summary) https://www.x4oxygen.com/article/hbot-telomere-immunosenescence-prospective-study-2020 [5] Effects of Hyperbaric Oxygen Therapy on the Pathophysiology of Aging – PubMed https://pubmed.ncbi.nlm.nih.gov/34784294/ [6] Hyperbaric Oxygen Therapy and Mechanisms of Aging: Clinical Study – Aging-US https://www.aging-us.com/article/203701/text [7] Hyperbaric Oxygen Therapy for Healthy Aging: Review – PMC https://pmc.ncbi.nlm.nih.gov/articles/PMC9156818/ [8] Hyperbaric Oxygen Therapy Effects on Aging Pathophysiology – Tel Aviv University Repository https://cris.tau.ac.il/en/publications/the-effect-of-hyperbaric-oxygen-therapy-on-the-pathophysiology-of/ [9] Hyperbaric Oxygen Therapy: Future Prospects in Regenerative and Anti-Aging Medicine https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2024.1368982/full [10] Hyperbaric Oxygen Therapy Human Study Reporting Reversal of Biological Aging Markers https://o2healthlab.com/wp-content/uploads/2023/11/Hyperbaric-Oxygen-Therapy-First-Human-Study-Shows-Reversal-in-Biology-of-Aging.pdf
u/mdeeebeee-101Worked for Michael Jackson.
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19r/AtlantaHere's What Happened This Week in the State House and State Senateznkatl800%3167.7stem cell therapy2026-03-08
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u/Atlanta_ManeSB 443 (Summers, R-Cordele) would increase the offense of obstructing streets, sidewalks, or highways (e.g. as part of a protest) from a misdemeanor to a high and aggravated misdemeanor. That won't be used to suppress protests at all. People jammed on a sidewalk could be arrested simply for standing packed like sardines.50
u/LastMuelLook at all that culture war bullshit.30
u/composer_7HB 1495, it's legitimately insane how all there's so many laws and programs the only benefit Boomers as if they're not the richest generation in this country. Regular people need these rent protections, among the other benefits these Boomers vote for themselves to enjoy.29
u/Radiant_Maize2315120 WHOLE hours? 🙄23
u/SavathunTechQuestion“Harbin, R-Tyrone) would allow gold and silver to be used as legal tender in the state. (Harbin, R-Tyrone) would require public schools to teach cursive handwriting by third grade” I shouldn’t be shocked these passed the full state senate but they’re both so dumb. I assume gold as legal tender is some “buy gold” culture war bs, and requiring cursive to be taught IMO is a waste of time as it isn’t required for anything anymore. Students would be better off with “learning to use the computer class” that teaches typing, file folder systems, etc as that’s actually becoming a real knowledge gap.19
u/harps86We are not sending our best.19
u/Louises_earsPossession is already a crime, doing so in the presence of a 13 year old doesn’t make it worse. We already have child endangerment laws, if that’s what is actually happening. Just seems like a way to add additional charges for no good reason.14
u/Commercial-Border227There’s no reason to increase rent on anyone of any demographic. Why should a person pay more for staying put than a new tenant? And should the landlord be able to increase rent by 25% on a 30 year old just because they’re younger? This is so wrong. Can’t afford to rent, can’t afford to buy!12
u/Loud_Fee7306Desperately need someone to confirm for me whether or not HB 1223 is what it sounds like. Because to me it sounds like they are attempting to declare that if a cop kills someone, they get to withhold the bodycam footage or audio from the public with the excuse of ″privacy interests″. Am I misreading? Am I Chicken Little-ing with the law here? Is this one of those things that′s already on the books anyway and they′re just changing the language around a bit? What is happening here?11
u/aumnrenSome of these are actually fire. 120 hours of pregnancy leave for state employees is great, sad it’s not for everyone else. The all included price tag is fantastic too. Tried of having to do the tax guessing game, even if I’m used to it.8
u/znkatl*If you want this delivered directly to your inbox, sign up for my free Substack at https://zachnikonovichkahn.substack.com/6
u/ATUGAJust read through the whole list… and didn’t really find much to be excited about. Usually it’s a little juicier…4
u/SofiNatural7Is the included tax price tag going to be statewide, and when is this implemented? All stores?1
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20r/covidlonghaulersIf money was no object what treatments would you try?Dazzling-Light-3487320%12067.6stem cell therapy2026-03-21
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u/LindenTeaJugIf money were no object I’d get a personal chef, a driver, a personal physical therapist, and a massage therapist to come to my home daily. I know those aren’t medicines but I react badly to meds and would love some daily help to see if it would help me heal!62
u/LifaceMoney is no object for me, but once you get to that point, it's not about money, it's about risk and effort. I entered a 60 day (and counting) bedbound crash from a fairly innocuous medication - low dose tirzepatide. You're not asking the right question here. The treatments you should try are not based on what someone with unlimited money would do, they are based on what fits your underlying test profile. I recommend getting comprehensive testing in order to guide your treatment options further.48
u/Kyliewoo123This question is asked all the time. I think what it’s really getting at is - what’s the magic treatment that most people don’t have access to because it’s too expensive (sorry if I’m wrong here). The reality is, “long covid syndrome” is just that. A syndrome. There are likely different issues going on for different subtypes of patients, and even within those subtypes people will respond to different treatments. LDN and LDA are commonly used medications that are fairly inexpensive. I think everyone should try each of these first. For lesser used treatments - I think if you have inflammatory factors at play, plasmapheresis followed by IVIG is likely the best treatment option. But I don’t see it curing anyone, just improving quality of life. Stem cell transplant sounds risky , and tbh I don’t know enough about it to make a comment. HBOT seems meh. SGBs help maybe 1/3 - 2/3 of patients with neuro symptoms. My true and realistic answer is - If money is no object, put it all towards hiring help so you can preserve your energy, properly pace and avoid PEM, and use any energy you may have towards something enjoyable instead of ADLs, chores, work (if possible… some like myself are too sick for that). Rest of the money goes to research. I personally donate to Open Medicine Foundation, PolyBio Research Foundation, and Dr. Jarred Younger’s lab at university of Alabama at Birmingham20
u/yellowpanda3Money is no object for me and haven’t found a total solution lol, but what helped the most was ivig and seeing a specialty doctor that operates outside insurance or any major hospital (who was able to get me ivig among other things)16
u/technician_902I would be be funding the research for diagnostics and treatments for long covid. No more having to guess what works.8
u/Impossible_Roof_JackNot aiming sky-high, but at-home HBOT. A 1.5-atmo soft unit runs $1800/month around here. A 2.0-atmosphere hardbody unit would be great to nap in. Ditto a 360* red light treatment bed. PEMF or trans-cranial magnetic stimulation. Don’t care if it’s off-label, the only limiting factor has been price. Acupuncture at least twice a week, basic IV treatments multiple times per week for generic brain fog, maybe trialling POTS treatments or recommendations for vascular dementia. Plasmapheresis or EEBO, possibly? My symptoms are almost all neuro now, so not sure if it’d make a dent. Diagnostically, finagling an fMRI may be nice. Just for fun, something like an Eight Sleep for cool overnight sleep.6
u/coconutoatsStem cell therapy. If money and pain/surgical anxiety were no object…6
u/CANfilmsI would put the best researchers on the planet, with the best equipment, and make it their sole purpose to find a cure for long covid6
u/Fearless_Fig_6568All of them. All of them5
u/Human-Committee3250Reincarnate 😍5
u/LeoKitCatDaratumumab, isatuximab, IVIG, and finally even a full stem cell transplant4
u/Choco_PawsI'm much better now so I don't want any more treatments but: When I was really bad, I didn't have an issue with money. I had an issue with my own capacity. When severe or very severe, you just can't buy yourself more energy to actually go get the treatments, the tests, etc. When you are stuck in bed in a dark room, there's only so much you can actually do... Some treatments or tests will just not come into your home, no matter how much money you throw at doctors. In my country, doctors are clueless and absolutely not willing to try experimental stuff. For example if I wanted to try SGB, I would have had to travel in another country. It was absolutely impossible in my state a year ago, I couldn't even sit up without crashing.4
u/Stranded_SnakeI would honestly do a blood transfusion or some type of blood cleanse if that’s the right word for it.3
u/Dazzling-Light-3487[deleted]2
u/MiserableInspector94Chromolyn sodium, Ketotifen. Natural mast cell stabilizers. All compounded antihistamines available on the market for my untreated MCAS. Treat my subclinical hypothyroidism. All compounded muscle relaxers for untreated severe muscle pain and CCI. Creatine, collagen. A taylor made Multivitamin without fillers and vitamins I react to. I would make my own infant/Nutritional formula so I am not emaciated anymore, gainweight and not lose wat muscle mass i have left. Medically supervised food introduction by allergist/Dietitian to up my 3 safe foods intake. Iron infusions, vitamin D sunbathing. Red light therapy. TENS machine / vibration plate. Full vitamin, nutrional panel and Elemental diet for SIBO.2
u/poignanttvI’d buy the Ammortal Chamber and Shiftwave chair for daily in-home use. With those two plus the Neuronic helmet, I’m fairly functional2
u/eefrIf money were no object, I would try every single safe, vaguely plausible therapy that exists. I'm six years in, as of today. I  would try basically anything.2
u/omegagaspI would love to try Maraviroc. It's so fucking expensive that I probably won't ever be able to and that sucks so much.  Also whatever my doctor wrote down as a treatment plan for me to try. I won't be able to do that unless I find a charity to kindly help cover the costs.  Other than that I'd move to a place that has an elevator and is generally more accessible, I'd get a driver, a cleaner, someone who cooks my meals and someone who helps me bathe regularly. If all of this would be taken care of, most sources of PEM would be gone and I'd have more chances of improving over time.2
u/East-Enthusiasm2504Car t Cell therapy2
u/ebaum55Id run every test imaginable that pertains. Gut zoomers, mycotoxin, every single blood marker possible, and other forms of testing I cant remember ATM. I feel this would and has provided so many answers to many people. Id upload all this data to multiple Ai platforms and use Ai to check other ais responses analyzing from a functional medicine perspective. This should get me very close to root cause(s) and a course of action. Depending on the answers most likely find the best functional provider i can find and compensate them to solve my particular case.2
u/kimchidijonIf money was no object I would be putting it towards long Covid research.2
u/danceintheflowersstem cell treatment seeing a medium or psychic having a safe home and not having to stress about become a climate migrant. or the weather causing flares and messing my days up. oh maybe a magic wand to fix climate crisis and expel the evil men starting wars, violence, etc.2
u/Useful-Secret4794I would summer at the coast like a consumptive Victorian. I would also try the HELP Apheresis protocol on Cyprus. If I’m going to be this sick, I wouldn’t mind a view of the ocean while I cope. Also, I’d get a personal assistant, as well as a housekeeper/cook. I can’t keep on top of appointments because every call takes so much out of me. I’d love to have someone who knows me well be able to man my calendar and make sure things don’t fall through the cracks. I’d crash less. Plus, a clean house and nourishing meals would go a long way.2
u/Excellent_Notice4047Someone is doing well with something called TruDose, I heard on FB. Might try that one1
u/curiouscuriousmtlTerzepetide, maybe some weirder peptides, maybe the weird thing where they remove something from all your blood (I can't remember what). I think just getting labs done a lot might show me what is going on if I compare it to how I am feeling at that time.1
u/brentonstrineDaily HBOT.1
u/caffeinehellDeep Brain Stimulation DBS for blank mind and anhedonia1
u/Sad-Abrocoma-8237Everything1
u/Evening_Public_8943I would try ivig and apharesis. Get my own hbot chamber. Hire a person for cleaning and grocery shopping. My meds currently: LDN, LDA, amifampridine. I will try rapamycin next probably1
u/BGM1988I would quit working and continue on my own pace without triggering pem cycles. Im slowly improving but think working slows my recovery. (Only work 2 days a week)1
u/Internal-Back1886for me/cfs stuff, RX Pros has NAD+ and peptide therapies that some people use for recovery. Dr. Patterson's RCCX theory folks tend to go with LDN first since its cheaper. stem cells are pricey but have the most anecdotal reports.1
u/apexnightmare333I would fly to Dubai , and ask for an inpatient treatment in the long covid clinic.1
u/srh-trzI would try every single treatment available !1
u/donotdiedragonflyIf money was no object, I would go to a functional doctor and try some of their treatments. I would also get a Pulsetto for vagus nerve stimulation. Probably a few other things I can think of. PEMF too.1
u/chubiraraMoving to a place with better conditions to my basic health needs. That would be my physical and mental therapy1
u/hoopitydGet tests until they figure out what strain I actually have. Make a custom mAb. mAbs seemed by far the best treatment in the beginning. Then "they" killed it to push vaccines. Now the mAbs only work if you are lucky and get the combo that matches your exact strain which they don't seem to test for. They just give you the general ones and use the failure to continue to say mAbs don't work.1
u/Historical_King333Buy a g*n and have texas roadhouse treatment. Im done.1
u/AfternoonFragrant617None. Nothing works1
u/Caster_of_spellsIVIG and MSC stem cells probably 💸1
u/Friendly_Boss_8725Plasma exchange and EBOO therapy1
u/Gimme-shelter-6_21What does the IVIG cost! Pemgarda was $9K1
u/happylightedFellow first waver. Fuck, and I can’t say this enough, this.1
u/OkEquipment3467Om thinking maybe IVIG1
u/Gardnersnake9Honestly, money being no object alone would be a huge benefit to my personal recovery, by giving me the security to simply rest without worrying about surviving financially or being a financial burden on my loved ones, in addition to a physical burden from my inability to fully help out arpund the house. The past 6 years have been a roller coaster of having to work to earn a living, crashing, going on short-term disability, recovering with rest and time off, returning to work, crashing again, losing my job due to attendance issues, being denied long-term disability, rinse and repeat. When I was able to take a full year off in 2022, living on my savings, and truly rest without the stress or energy demands of a job or having to find one, I actually recovered. Then I returned to work in January 2023, caught COVID two weeks into my new job, and began the se cycle all over again in March 2023.1
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u/ComplexologyI'd probably go for bruce patterson's work. https://www.covidlonghaulers.com/north-america/home
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21r/tresslessReducing Fibrosis in Hair Loss: Topical Pirfenidonenoeyys530%3666.4stem cell therapy2026-03-26
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u/Lev1nnHi, i cant use minoxidil foam or topical on my head due to seborreic and Malassezia. My dermatologist said your hair loss is not AGA im thinking my hairloss is due to dermatit and malassezia want to ask you think that gel gonna help to recover my scalp?3
u/HelpingmehelpNice work. Very interesting.2
u/Zealousideal_Sun6495Very interesting. What are your thoughts on copper peptides to support scalp health and possibly hair growth? (As an adjunct to fin/min ofcourse)2
u/Ralphiedog11Any way of getting this in the US?1
u/Luke10191Great content as always. Can you make a video regarding how a female should deal with androgenetic alopecia?1
u/AlakagomIs there any merit in introducing anti-inflammatory products without obvious inflammation in the scalp itself? Might not be visible but still affecting the hair and the stem cells in some way? You mentioned Wnt/B-catenin modulators which we know has a role in hair growth regardless. To me it sounds like Pirfenidone might play a role in a Dutasteride/Minoxidil stack through its mechanistic process. Hair loss is clearly not just a DHT sensitivity.1
u/aguedoudedaaSuper interessant. Tu as noté une amélioration depuis que tu utilises ce produit ?1
u/mewingprofileDo you apply it to the whole scalp?1
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u/jeansarkozy1607could you make some pirfenidone with your own patented vehicle you use for minoxidil sulfate?
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22r/stemcellsPlease help me get stem cells to help me walk againAdrianG_23440%4866.1stem cell therapy2026-03-07
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u/ConditionCorrect4065Hey brother stem cells do not work as well as you think they do. The science is not there yet. Save your money and spend it on hookers and happy endings lol. Just kidding but not really though. I spent over 50k on stem cells from a very reputable clinic in Colombia that starts with biox and I got almost no improvement. Just wait a few more years because there are other options that may be available and may be more beneficialnegative22
u/Zergs1Idk if that will make you walk dudenegative7
u/Warren_slIn the mean time a good daily protocol to help with nerve regeneration would be having a good omega 3/vitamin/mineral intake combined with ErinaMAX by Nootropics Depot possibly stacked with their Tigers milk. I’ve had nerve damage in one of my fingers induced by frostbite years ago heal from this and others have had brain and nervous system benefits. I wish you the best in your journey and I’m sorry you’ve endured this.positive6
u/tfrescaYou’ve posted before. Folks told you that the cure you are looking for won’t come from this treatment.negative2
u/ZumbgrlHey Adrian, have you looked into studies/trials?? ?neutral2
u/mistersilver007Just wait for nervgen to get accelerated fda approval on nvg-291. This is your best bet.positive2
u/omarfx007🙏positive1
u/Confident_Web3110Immunotherapy mx. saw someone walk after having ms. They will tell you if they can help you or not.neutral1
u/SoManyQuestions5200Hey man there is so much misinformation in these comments, its disturbing.do a google search for those medical research institutions that have successfully done restored walking and contact them directlynegative1
u/TemporaryCod5601Hey brother, May our Heavenly Father bless you, may He take your pain away and lessen your burden. May he guide you divinely, with Angels by your side on your journey back to health!!! In Jesus's name, Amen.positive1
u/Mr-CantaloupeThere is very little chance you’ll be able to walk again with stem cell therapy; the data doesn’t support it. In a few years, maybe, but a lot of the ‘positive’ outcomes in trials are people’s quality of life improving, and a lot of scientists/researchers argue that a big reason for their improvements is from the rehab/physical therapy. That doesn’t mean to give up hope, it HAS been done, and as time goes on the probability will get higher. Your best bet is applying and somehow participating in Clinical trials (I know, easier said than done), and there’s also ‘Neuromodulation’. Those two treatments would give you much higher odds to walk again than stem cell treatment. Please don’t get scammed and give $30,000 to a company in Panama that promises you the ability to walk again.negative1
u/Severe_Place_119This quote is pricey. Go to YOU regenerative clinic in Medeillin Colombia. Sure they can beat that price for you. It’s a small clinic with specialist doctors.neutral1
u/Ok-Individual-1154Rooting for you!positive1
u/CyruslegoGod bless. I wish there’s something works for youneutral1
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23r/InterstellarKineticsEXCLUSIVE: Swedish Scientists Built a Scaffold That Convinces Your Body to Regro...InterstellarKinetics4210%266.0stem cell therapy2026-03-07
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u/InterstellarKineticsWhen a bone breaks too severely to heal on its own, surgeons either take bone from somewhere else in your body creating a second wound or they put in a metal implant that your body never fully accepts. Swedish researchers just published a scaffold that does neither. It is implanted completely cell-free but it preserves the biological signals that tell your own stem cells to migrate in and build new bone using the structure as a blueprint. No donor cells, no rejection risk, no second wound site. If this scales to clinical use which current surgical procedure do you think it replaces first?4
u/dunce_charmingCool tech... I hope it can be scaled to normal use.3
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24r/ScienceOdyssey✨️China reports experimental stem-cell therapy restoring insulin production in s...Purple_Dust573424850%5965.7stem cell therapy2026-03-03
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u/DreboomboomChina doing shit the US refuses.negative35
u/R3D4FPharmaceuticals in the U.S. would bury this technology faster than an oil company buying up green energy patents. All hail corporations that write the laws, elect the politicians, and are made all powerful by Citizens United.negative12
u/Puzzleheaded-Bus1331How stupid are people in the comments? It's just some preliminary research guys. ?negative5
u/JaseKianThis came out two years ago and diabetes is still rampant. ☹️ (I work at a peds endo & diabetes clinic)negative2
u/PsychologicalMud3108I doubt this is real. I have diabetes. If there's a cure. Let me have it. I'll believe it when I see it. Give it to me and when my blood sugars are stable, I'll believe it. But not before. Oh! [Insert excuse x, y, z here] That's convenient. That being said, Trump is a narcissistic asshole with a brain the size of a tic tac. That needs to be removed from office by any and all necessary means, by the fastest way possible, and put in jail with ALL of his assets seized.negative2
u/Lofi_Joe[removed]neutral1
u/Jynae_Sin-QwaWhile Americans... we're bombing the jets we gave to Iran ...negative1
u/No_Cupcake7037Yay!positive1
u/Common-Sherbert4891Hey… uh can you cure herpes? Asking for a friend. ?negative1
u/[deleted]Wow just wow. While the US acts like Israel and bombs kids for what!? ?negative1
u/[deleted]Thanks to trump we won't get this here.negative1
u/meatmaxxer3000They’ll probably experiment on their abducted children thus producing better organs for them to harvest for the elite.negative1
u/detter1987ând at the same time, americans drink bleach and shut down science fundsnegative1
u/TechnicalChipzNothing but positive comments about China on Reddit. Has China bought stock in Reddit by chance? I don't see anything about the human organ farms that they have? Or the social credit score? So what's the deal? ?negative1
u/MaxBromosecsuali was about to take the image and change the wording to something else....neutral1
u/Jairoglyphics1Never thought I’d be jealous of Chinanegative1
u/migmac71I just wonder where they get all the stem cells needed for such and other studies...neutral1
u/420-eurekaI hope they get it. That is fixed diabetes. The US is going down in the dump because of the pretender and chief.negative1
u/Loose_Plane9790Guess I need to get a passport and prepare myself for a trip to china in the near futurepositive1
u/[deleted][deleted]neutral
u/Ok-Chemical-1020Man, all these advancements right after the USA leaves the WHO..... Wonder what that's all about.negative
u/No-Option-7010Gods that would change my life forever if it worked and the US had it. And yes they would bury it and would rather make money at the cost of suffering of others.negative
u/Supar-Morio69meanwhile in the...neutral
u/Life_Acrobat_2408Incrediblepositive
u/Ethe-Real-6837With the Rapist pedophile Trump who has his head stuck up some child's butt, and refusing science, china is going to wipe the clock of America over the next couple of years with regards o science.negative
u/Print-OverThat's great news.positive
u/KenyMooreHey MAGA are you tired of winning?😂😂😂😂😂 ?negative
u/dirywhiteboyChina been doing their shitnegative
u/Pacety1I’m pretty sure Cuba basically cured lung cancer too. All our enemies are losing so hard.positive
u/IntroductionGrand857China the leader of the world 💪positive
u/EagleEyes0001I’m so jealous. We could be doing this here. But I guess we have other things on our mind.negative
u/JONYLOCOThis is type of news that pharmaceutical companies would want a war to happen and distract everyone in the world...especially America $$$ dictates everythingnegative
u/NightstandsHearts and minds is a better strategy than bomb bomb bombpositive
u/Neither_Relative_252The US doesn't want this.. probably has the cure for alot however the payments are in illness i.e insulin, supplies, accucheck machines, complications, blindness, amputations therefore we will call this a hoax and denounce it especially since we no longer believe in science.negative
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25r/malehairadviceHow to fix hair loss(most naturally)bankerbilbo620%2065.2stem cell therapy2026-03-29
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u/phishnchips_Do this if your hairloss is so minimal that you can afford to try this out and see if it works. Or if its so bad at its a last ditch effort. Otherwise take it from me and just do topical fin/min if you’re concerned about sides.30
u/Random_fellow9Fin and min11
u/Different-Sky4553Nonsense.7
u/randomshitlogicFinally a 6-7 I can related to! Take that kids4
u/SuitableRelease4323Apply rosemary oil daily? You serious?4
u/My_Rhythm875I went through something similar, and honestly focusing on scalp health consistently made a big difference before even touching any meds. Along with things like rosemary oil and gentle scalp massages, I added red light therapy and it actually seemed to help with thickness and overall follicle health. I’ve been using this panel from longevity based, and over a few months it felt like my hair looked fuller and healthier alongside a solid routine, definitely not overnight, but noticeable with consistency.2
u/S_portzyWhat is your story in using these methods, from what NW stage to recovery within a year? For many of the NW stages on the scale you showed (4 and up), gaining ground with the methods you mentioned including pharma is a long road / very unlikely to recover because of the amount of fibrotic hairs a person has at that point. Even from a NW3 it’s at least a 2 year journey for many that aren’t strong responders to fin/min. As a NW3 who’s been regrowing dead zones…I actually am not against any of these methods and I do use some alongside min + tret. Caffeine has been in my routine for a while now and I do think it has value. I use a caffeine serum rather than a shampoo, my latest iteration is I massage it in: caffeine, niacinimide, capixyl ahead of IRL session. I noticed a pickup in regrowth speed after moving to this. I found oral saw palmetto to be of no value and eventually did get some odd mild sides from it…so stopped. I do use it topically though with more success.1
u/First_Tone4187Idk, I felt Great when I went bald1
u/FreedomKnownThis entire post is AI written1
u/I-E-TazzI ain't reading all that, try minoxidil if you don't use it already1
u/futurafrlxDo all of this instead of proven ways to correct hair loss and you will be bald in no time.
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26r/MultipleSclerosisIs this it? When doctors tell you nothing more can be done, go to physio, and go...mermaidoutofwater000380%3364.7stem cell therapy2026-03-12
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u/ChrisEUI am (and have been) in a very similar boat. PPMS, wheelchair, heavy fatigue, no DMT and nothing the docs can do for me. It may be the end of the line for the docs, but not for me. I still have the rest of my life to live and I refuse to sit back and die. I am working a different job now (as a specialist with specific knowledge that's rare, at home, part time, just enough money to live, but indispensable for my employer), so I don't have to worry about that at all. I can work there until the cows come home. One problem less to solve. Yes, I am lucky about it. I am using motorized wheelchairs that are cool and fun to use (This thing and a souped up device that pulls my manual wheelchair up to around 50km/h). I learned lockpicking for manual dexterity and hand/eye coordination. I am drilling deep into current MS science and AI technology, writing systems that actually help people with their work. I develop drone software that's autonomous. Just because the docs can't help me doesn't mean I'm helpless - or useless, for that matter.16
u/Adventurous_Pin_344Hi friend. I was diagnosed almost 14 years ago, started having symptoms 18 years ago, and I deal with a lot of the same shit you are describing. I appreciate the optimism shown here, but unfortunately, there aren't any medications that address our disease stage. We at least are at the next stage of MS research. Current meds do a great job stopping acute inflammation in the form of lesions, but they don't stop whatever is causing smoldering inflammation. (Ocrevus can a little, but they aren't sure why...) You could do what I do, and spend far too much time on clinical trials.gov, and look for trials that are recruiting for non-active SPMS cases I am going to try and get into the next stage of CAR-T trials and have been trying to get into a Frexalimab trial. Frexalimab is a BTK inhibitor, a class of drugs that show promise with slowing smoldering disease by limiting microglial activation. Unfortunately, the first one of these to come up for FDA approval (Tolebrutinib) was denied in December. The FDA said it created too high of a risk for liver damage. I also subscribe to Gavin Giovannoni's Substack "MS Selfie" because he is a huge believer in our stage of MS being the "real MS." For now, I keep working hard to stay active and mobile, and use what symptom specific treatments I have - Botox for my neurogenic bladder, trulance for my neurogenic bowel, Tizanidine for my spasticity. But it's frustrating and scary to not have any meds to slow our progression. For now, keep an eye on trials! And read Dr. G's stuff!8
u/cbrooks1232PIRA is short for Progression Independent of Relapse Activity. It’s also sometimes referred to as smoldering MS. If I were diagnosed as having PIRA MS the first thing I’d do is get a second opinion. From an MS specialist neurologist. If PIRA MS was confirmed, I’d find an MS clinic/hospital that was considered cutting edge and learn about potential treatments that many of us with more controllable MS might not know about. Your doctor’s response mentioned in your title is simply unacceptable and uncalled for and even if PIRA is confirmed I’d find another doctor.8
u/Amazing_Lead9946Hey, NO, thats not it That's all doctors can do YES But there is a lot for you to do youll find out that there are many things you'll have to do Think of yourself right now as a high-performance athlete no bad nights, stress minimized, good healthy ending aware of inflammation in any form No its NOt IT If you believe it your not doing enough research7
u/JCIFIREThat's pretty much it. I was on Ocrevus for 7 years and only got worse. No new lesions in years. Probably had MS for 20 years before I was diagnosed at 43 but never had any symptoms so I didn't know. I am now on Zeposia and still just getting worse. Getting worse coincided with going through menopause at about the age of 48. My walking, balance, and nerve pain are my issues. Nothing more they can do. I don't get MRIs anymore because there is no point. It's not going to change my treatment. This disease has ruined my life and it fucking sucks. I'm so sorry you have it too. Unfortunately aging is not on our side. I have read that getting worse usually hits between the ages of 45 and 50, and that's exactly how it was for me.5
u/Dramatic_Mixture_877Have you tried dalfampridine (Ampyra)? I asked my first neurologist about trying it, and it's a gamechanger! I accidentally ran out last year with no refills, and by the time I got some back in my system again, all my coworkers were worried about me - it's not just walking that it helps, it seems to be overall coordination for me. I've also learned that wearing inappropriate footwear will really affect my walking speed, overall tiredness, and balance. My first neurologist kept telling me that if I would go to the gym and work out, I'd have more energy - I told him that if it were that easy, I'd be there with bells on every day! But it's an either/or in my case; I can go walk/work out after I get off work, or I can tend to the dogs, chickens, and us getting fed. There's no and in that equation. My current neurologist totally gets where I'm coming from - he let me try a gamut of stimulants; nothing has helped. Modafinil, armodafinil, Sunosi, Ritalin, Adderall, Adipex, nothing. I asked to go back on the Adderall because it helps me stay focused at work and smooths out my typing for some odd reason (unless you count AuDHD, lol).3
u/mermaidoutofwater000Thank you, I also needed to hear this! I agree and thanks for reminding me that do much is up to me ( all of us) . Like eating right and not stressing, getting rest. I just want to make sure that there isn’t also a therapy that can help as well.2
u/mermaidoutofwater000Thanks for sharing and thanks for the optimism! It is up to us to keep living and adapt and it sounds like you truly have. Your work sounds really cool!2
u/Affectionate_Wish795Please watch Living Proof documentary on Prime. My naturopath also has had success with her MS patients. Theyve gone from using a cane/wheelchair to now jogging. Im hoping for the same or similar results with PPMS.2
u/alex_rasti13Complemento la medicación con mi estilo de vida, práctico ayuno, tomo el sol, hago dieta carnívora y ejercicio. Estoy diagnosticado hace más de 15 años y estoy muy bien. Creo que el estilo de vida es muy importante, siempre combinado con la medicación.2
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27r/Ayahuasca24 hours upon returning from an aya retreat, my partner of 5 years got very hate...This-Sky9770200%7364.5stem cell therapy2026-03-25
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u/INKEDsageSounds like very manic behavior. Probably has an unbeknownst underlying condition that is a contraindication to the medicine. Ayahuasca can exacerbate certain conditions. In my opinion, your focus should be on yourself and your son. Find as many resources as you can. Reach out for support. Get yourself and your boy safe. Your husband’s behavior might be concerning and you obviously want to help but right that is at the bottom of the list. You don’t have the luxury of trying to save him when you have your boy to care for. Also, your husband does not seem like he’s a in good space and is a liability to yours and your son’s wellbeing. I’m so sorry that this is happening to you both. Take good care and I hope you find everything you need soon.42
u/A_MurmurationWow. In ceremonies I have attended the facilitators were VERY clear about this great advice: First three days back is about grounding. Touch grass, no media, journal. Next two weeks to three months, no major decisions like job changes or ending relationships or giving away all your possessions. An hour long integration call at the two week mark to check on you. I really valued that they did that22
u/Soul_trustWas this Rythmia? Sounds like it was. They've totally screwed with him. The place is hell on earth, and I recommend you research it so you don't personalize what your partner is going through.8
u/BearsOwlsFrogsI don’t know where you’re from, but in a lot of places he can’t legally kick you out without notice. If he’s wanting to pay for an apartment, get the money up front for a years worth. He might quit paying a few months in. He most likely had you move back in to get unpaid childcare and housekeeping out of you. It was probably easier for him to be civil when he was gone 5 days a week. Even if he starts behaving again, it’s obvious he’s not safe as a partner.6
u/Sufficient-State3720So sorry you are going through this now. Please name this centre! Did they sell this stem therapy themselves that sounds crazy? Sounds like he needs a lot of extra support with his mental health urgently and integrating the retreat and you yourself need your own support too! I favour small retreats of max 5 people with at least a week or two afterwards with trained experienced grounded therapists who can give 1:1. The reality is overpriced retreats of 30 plus where the company ceremony control is poor. The shaman if there is one will just sing for the space and not individually so much. People leave for the real world too soon while they are still vulnerable. This is what happens with ayahuasca as a westerner business. I hope things settle down and his senses are regained and stress goes away5
u/Tiny-Art7074Just leave him. Seriously, stop wasting your time. Hate to say it but not everything is fixable or worth fixing just because its broken. He doesn't seem to be able to care about you and is dragging you along only so he isn't alone. Not worth it.3
u/astraladventuresThe post ayahuasca break up is amazingly common.3
u/Sea-Research8302im really sorry for you. I'll keep it brief because it's pointless to judge such things without hearing the "whole" truth or at least only your opinion and not his.  From experience, I know that after such retreats, the nervous system can be raw, and one might therefore go into attack mode as a form of self-protection (more unconsciously than consciously).  Perhaps there's more to it, though, and he had an "intuition" that now makes him believe he's better off without you.  Unfortunately, that's something you have to accept.  Bipolar disorder also sounds suspicious. I would wait and see; there's probably not much more you can do if he's actually in a different state or even psychotic due to the retreat (I've experienced this with my husband repeatedly...). All the best!3
u/sbarretI could not read everything, but really, you should focus on your kid, there's some narcissist/maniac behavior there but really focus on the kid and what's best for both of you. Ayahuasca has pretty much nothing to do with this, it's a brew it doesn't turn people into assholes2
u/Enough_Extent_2827Op I felt like reading this post the vernacular wall so much about him and his interests. . . I wonder if you might benefit from thinking about what you want and deserve.... Like : do you want and deserve a partner with this type of interest and response to you? I hope I'm not bulldozing here. Just hope you are caring for your on wants and needs and boundaries. It sounds like he has a lot of unacceptable behaviours.2
u/Revolutionary_Bike54Are you sure he went to the retreat? He travels with work, while you're home. He goes back and forth about the relationship.2
u/Ashamed-Internet8373Gurl your husband bought back some bad forces entites with him . The shamans can only send out an invitation they have no control of who accepts it . Unfortunately judging from what you posted things are only going to get worse for him . He will isolate more & spiral further & his mental health will slowly deteriorate. I would advise you to be patient. Also have noticed any supernatural things happening in your home or happening to him or you?2
u/Frequent_Truth808Sorry you're going through this. Hope you can find some sort of peace and grounding. Also, altered states are sacred. Selling and offering services during that time is not okay. It's actually a huge red flag. That being said stem cells for autism is not snake oil. There is research showing positive impact. The first thing that came up when I searched online: Stem cell therapy for autism remains an experimental treatment that has not received FDA approval for this specific condition, though clinical trials have shown promising results in reducing symptoms.  The only FDA-approved stem cell products in the U.S. are blood-forming stem cells from umbilical cord blood used for blood disorders, not for autism spectrum disorder (ASD).  Research indicates that mesenchymal stem cells (MSCs) and umbilical cord blood may help alleviate autism symptoms by reducing neuroinflammation and improving immune regulation, rather than curing the underlying genetic causes.  Several studies and anecdotal reports suggest improvements in social interaction, language skills, and sensory issues following treatment, but these findings often come from small trials or non-controlled settings.2
u/ProcrastingineerHonestly it sounds like you are in a relationship with a narcissist. You are seeing the result of the mask being forcefully ripped off. You're probably right that he has hated you for a long time, and he can't keep up the facade after being shown his true self. Psychedelics often can't really fix narcissists, but they can sure destroy them. You are likely watching the building of a new and stronger mask. The yoga studio and Buddha statue are almost comically stereotypical outcomes when people who really can't handle psychedelics get exposed to them. also see:2
u/erinaceousfoxI'd be concerned about the manic part as psychedelics triggered my bipolar years ago. First off, they failed with the screening process. Were they to be serious they would ask about family mental illness and screen out people with bipolar running in the family. Here's a good list to look out for in regards to bipolar: Elevated/irritable mood beyond baseline Decreased need for sleep (not feeling tired) Racing thoughts / rapid idea switching Inflated confidence or grandiosity Increased talkativeness / pressured speech Distractibility Impulsivity / risk-taking Economic behavior: Increased spending / impulsive purchases Unrealistic financial decisions or investments Reduced concern for consequences of money use2
u/Big-Performance5047Wondering if he is addicted to something1
u/TuckerStewartYour partner sounds very deep in the medicine, and you mentioned his family has a history of bipolar. After searching in the comments to confirm, I knew you were referencing Rythmia based on the stem cells. Rythmia is the most incredible, magical, beautiful, and supportive ayahuasca SANCTUARY in the world. They have a specialized program that in the end, you are told to ask the medicine to show you who you've become. Looks like the medicine is showing him EXACTLY who he has become- a belligerent, temperamental, abusive loser who wreaks havoc in his family's lives. I hope he sees who he has become, and he gets the proper support and help he so clearly needs. You also see who he has become, and without self-awareness he could stay this way. The medicine is just a tool. A beautiful, hard tool that can completely change the course of your life. It's up to him to get help and look at himself fully in the mirror. I hope you take care of yourself. And anyone reading, this, Rythmia is phenomenal. I go once a year for a tune up and it has changed the complete trajectory of my life. I am forever grateful for this place. It is insane there are so many shit-talkers of Rythmia who have NEVER been (they can't afford it lol) and are victims to life and are so quick to BLAME. Do the inner work and get honest.
u/miggins161014 day old account with no other posts or comments? Something smells off here to me-4
u/NonGMOman_Brand New account. All these Bull shit posts using AI Enough already!-10
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28r/eagles[Berman] Landon Dickerson went to Medellin, Colombia, to undergo stem cell thera...indig0sixalpha4750%8363.7stem cell therapy2026-03-09
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u/burratnaExciting Whites and the Stem Cell Boysnegative268
u/jawadali415Can we send Embiid therenegative248
u/Alive_Bodybuilder288I am Queens Boulevardneutral84
u/bkist267Columbian stem cell therapy is so hot right nowpositive66
u/HyrogrifixNeither guy looked right last year, them Being healthy this year is more important than signing anyone in free agencyneutral44
u/mb0205OL was playing crippled last year Jesus Christ lolnegative20
u/larson00I didn't know this was even a thingneutral17
u/wire28Our fate is in your hands, Colombianeutral10
u/HotSaucePalmTreeslol the US healthcare system is a fucking jokenegative10
u/Spare-Half796Columbia is heaven for large strong men who have joint problemsnegative8
u/IllbloodHope I can get stem cell therapy for my back pain one day. If only we gave a shit about medical research in this country, who knows what else could be done with stem cells.positive8
u/Overall-Specialist37My purpose of travel to Medellin? <squints at sweaty crib notes on palm of hand> uhh umm stew celery theory ?negative7
u/huck_I guess Cam Jurgens was the guinea pig.negative5
u/Competitive-Umpire18“Stem cells”neutral5
u/baconcheesytots_They just going for the Colombian girls with fat assesnegative5
u/ZhangtheGreatI think a lot of us knew they weren’t healthy last season. Hopefully, we’ve fixed our major OL woes now.positive4
u/Responsible-Fix9684[deleted]neutral4
u/rodrigoa1990What is his injury, specifically? I know it's his knee, but like, ligament, meniscus? And why is it lingering so much ?negative3
u/Onlypaws_I’m sure the blow helped, too.neutral3
u/scottylightningHis Uncrustables are stem cell fillednegative2
u/doughball27having worked with researchers who are studying this stuff, there is absolutely no evidence yet that stem cell therapies work. this is just really expensive snake oil, unfortunately. the fact that he had to go to columbia to pursue this should be all you need to know about its efficacy.negative1
u/CardiffGiant7117lol drug test inboundnegative1
u/Forsaken_Crow_7707As long as the stem cell boys didn’t pick up any nose candy habit while in townnegative1
u/redditzaneIsn't Medellin where Escobar was based? ?neutral1
u/gimmethatfiletofishThis will be worth it when we get a highlight reel of Jurgens and Dickerson pancaking defenders set to the theme song from Narcospositive1
u/MathRockEnjoyer420Nah our O line is still gonna be cooked lolnegative1
u/WhyDoTheyAlwaysRun"Stem cell therapy"neutral1
u/phillabadboy05I would imagine this would be pretty successful for the average person who's body isn't pounded every week. I wonder how long it could effective for a professional athleteneutral1
u/PA_MallowPrincess_98Philadelphia Eagles 🤝 Philadelphia Phillies Finding new ways to heal injuriesneutral1
u/osirus35You always hear praises of stem cells but like is there a recovery timeline where the healing from the stem cells is most effective? Like will they be 90% this year vs 50% last year. ?neutral1
u/MyKidsArentOnRedditAnyone with some actual knowledge want to chime in? Is this therapy real or is it a bunch of BS? If the former, why is it not offered in the US? ?negative1
u/mmuoioGod I hope it works, we need them both playing better.negative1
u/AC_deuceyGuess they both love medellin with stem cells Rest of the league like “we would have sacked Jalen if it weren’t for those Medellin kids!” That’s all I got, I’m outpositive1
u/Different_Inside_546There both cooked…neutral1
u/Ill-CommsOLINE heavy draft incoming.negative1
u/weezyverseA reminder that cocaine is all natural.negative1
u/Aerolithe_LionWhy of all times of the year are you breaking this right nownegative1
u/burnernov2023Please go easy on the tush pushes this year Nick.neutral1
u/Drewraven10Should’ve did it after the Super Bowl tbhnegative1
u/phthalo-starMom get in here, the whites are getting ready to be exciting again!positive1
u/phillabadboy05I would imagine this would be pretty successful for the average person who's body isn't pounded every week. I wonder how long it could effective for a professional athleteneutral
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29r/ValueInvesting$SLS Part 2 and FINAL (Deepest Due Diligence for REGAL Trial) (Results from Mach...Confident-Web-7118300%2963.2stem cell therapy2026-03-08
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u/Accurate_Pay_2242Love SLS10
u/Confident-Web-7118Thanks for this. I’ve previously read both parts of your analysis and tried to stress test it myself. Not having biostatistics expertise this has been hard to do. I began to think about other ways to prove the trial is working through looking at other evidence (investigator testimonials, clinical supply and logistics, etc). Did not find anything to contradict your conclusion Have you looked at any of these avenues? Any new thoughts or evidence since you did your analysis a while back?7
u/Remarkable-Big-9849Hello, We discussed things a few days ago on one of these threads and I've spent the last week doing even more testing and wanted to update you since a few things you said inspired me a bit. First you mentioned I was using an agnostic 50% prior and that a literature-informed prior would be closer to70% with a pessimistic prior at 20%. While I agree that if we take overall oncology phase-3 trial success rates and the biological mechanistic plausibility, it would imply around 70% as a reasonable prior but vaccines and immunotherapies like this especially in diseases like AML have had much lower success rates so I actually think a 20-40% prior is more supported with the 40% being driven by the phase-2 evidence and biological plausibility. Second, you mentioned that you looked at what the failures actually looked like and that inspired me to look into the failures myself and other trial data where the trial was a statistical miss but the biological signal was strong enough that another trial happened. Using those conditions, I was able to separate out failures where the drug works but failed due to statistical power and another trial happens. Combining that with the prior range I mentioned earlier, I got the following scenario probabilities: Final derived scenario probabilities Scenario Probability Strong success (cure tail) 70-85% Moderate success 8–15% Statistical miss but signal 3–6% No effect 1–2% which actually brings me a bit in more line with your reproduction of my methodology where you got 98-99% chance the drug works. I do think we should treat the statistical miss scenario as a 50% value haircut due to extending the timeline out a few years and increasing early costs (which may or may not increase dilution, as they do have a lot of cash) I also wanted to share a histogram I produced in my initial testing for the probabilistic feasible region for cure fraction but reddit doesn't let me post images in a comment it seems. So here is some of the data: Number of feasible draws: 50000 Mean implied cure fraction: 0.578 Median implied cure fraction: 0.590 Probability cure fraction >= 0.20: 1.000 5th, 10th, 25th Percentiles: [0.39379246 0.43575868 0.51072057] Probability of Cure Fraction above 35%: 0.9784 Talking about the economics a bit: Revenue=N*Penetration*Price*Duration and we know that a cure fraction is going to increase both Duration and effective N over time as patients stay alive longer so if the average treatment duration without cure is represented by D and cured patients that stay treated by kD, we have: Duration=(1−p)D+p(kD) =D[1+p(k−1)]= D[1 + p(k-1)]=D[1+p(k−1)]=1+p(k−1) where k represents how much longer the patients stay treated and p is the cure fraction. If the baseline therapy duration is ~12 months and durable responders last 3-5 years on the treatment, we would have a revenue model of 1 +2p to 1 +4p and if an acceptable cost per quality life-year gained is ~$100-150k in the USA then we could have a 2-3.5x revenue effect over baseline (current population) based on my histogram data. If the drug is extremely effective and adds 10-20 life years then the total price might be limited due to payer pressure so I didn't want to model that out.5
u/Limp_Leg3323Really appreciate the insights you shared here! Stress testing can feel like trying to solve a Rubik’s cube blindfolded, right? I’d love to hear if you’ve unearthed any fresh evidence or thoughts since your analysis!5
u/Adeus_AtticusI’ve already thanked you for this but will do so again! Do you see the basement value rising the longer REGAL goes on?3
u/hariharsharmaJust curious on 2 things: I don't see any disclaimer on this post, is it sponsored? don't get offended please. Just curious. how far the stock will go if the result is positive as the model/analysis indicates most important, how likely SLS will release more stocks during up coming meeting in 2 weeks, like they did in early January 2026 taking benefit of higher market price. Thanks for reading and responding my comment.
u/Ok_Choice_3228I evwn got bored of scrolling. I can't imagine anyone has a whole free day to read all of this...-6
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30r/Hairtransplantday 3 post OP absolute hair , doctor R.Enough-Bother6932270%3363.2stem cell therapy2026-03-13
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u/ThemeAppropriate575Hello bro, that looks amazing, do you have pictures of the sides and back before HT please? Your case very interesting because I think we are very similar, thanks5
u/JohnMcCainsCapturersvery interesting case and would love to see how it looks like at around month 7 onwards, i hope you wont have to come for a 2nd time!4
u/Forever778That looks amazing. How long was the procedure? How much does Dr R do? What was the cost? And was it easy to go out travel after? Thank you!2
u/Ok-North10Dr Ratchatborn?2
u/markiemark6I’m on day 3 as well.. and this healing process is rough. I swelled a good bit and my donor area aches pretty good.. how’s your experience been so far?2
u/Enough-Bother6932<image> day 6 back in us after long flight ✈️ today2
u/go_get_your_hyungThank you for posting!! I’m booked with her too! Albeit, a long time from now. Questions: What is her HBOT price for the 3 sessions? Just trying to get a ballpark idea. Do you do HBOT in morning —>rest—> LLLT in the afternoons and if not, how does the sequence go? I see you are only staying 6 days post-op and realize you will not be taking advantage of it, but did you see if they offered a service to remove scabs between day 10-14? I have seen some clinics offer an olive oil treatment for that; regardless of how they do it i’m terrified of doing it myself so was hoping they could. I’ve been through all her pre-op and post-op instructions. Anything you have learned more or would do differently if you had to repeat? Is a neck pillow enough, or would you bring an inflatable wedge pillow too?1
u/Enough-Bother6932<image> Day 5 post op after last wash and llt at absolute . bittersweet leaving tomorrow, as id love to stay till scaps come off . They take such good care of you . If you can stay for 10 days post id recommend so you dont have to do it yourself , but also they have given me the tools and knowledge i need to perform the rest of the care1
u/Enough-Bother6932<image> donor day 5 post op1
u/Enough-Bother6932<image> Day 8 POST OP back in US as of yesterday1
u/Enough-Bother6932<image> Day 8 donor area1
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31r/sellaslifesciencesNew Sterg Postmad_papooser890%6162.4stem cell therapy2026-03-06
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u/United-Collar-944He doesn't actually talk much about the REGAL result itself. Instead, he talks several times about what happens after REGAL – new indications, platform thinking around GPS and the broader WT1 track. This seems to be a pattern in his communication on LinkedInpost the last month or two: REGAL is not presented as a single binary event, but more as a first step if the data holds up. Maybe I'm overinterpreting, but it's interesting that the focus several times is on post-REGAL strategy, not just the study.26
u/CaptainWhiplashMy man Sterg ain't mincing words talking about "curative". Fellas, this is bullish af23
u/mad_papooserSomething that is being overlooked is that while Sterg and SELLAS may be technically blinded to the patients, they know 100% real time if GPS is working. They are managing the supply chain!! The know every vial that gets ordered by every testing center. Real time. They know if patients are living longer based on live order volume at each center.20
u/mad_papooserOr…bulls on parade :) Anyone notice that word “curative” in there? He’s dropping breadcrumbs to us. This thing is hitting.20
u/TemporumdeiPerfect timing.14
u/ShawnniegUAn<image> What is this statement. No more maintenance but cure???12
u/Desperate_Work_7742In the movie business, these are called “Easter eggs”. Very encouraging and I think there would be ZERO of these types of updates if things were trending in the wrong direction. I remain VERY BULLISH on a binary event and hopefully and meaningful buy out 🔥🔥🔥11
u/neo2551At least, he seems bullish on his assets.9
u/Such-Leg4898I like it............ but ........... to be honest I don't think he would write it while in the middle of buyout negotiations. Therefore I don't think we are that close to an announcement. I'm super bullish but that's how I view it.7
u/Prestigious_Age5422Guys, do you know how risky it would be to post this frequent of content and the nature of this content unless…. 🙏🏻7
u/nicklank4This is huge!! FOMO will kick in today and take the stock over $66
u/United-Collar-944<image> 👏👏👏3
u/bsep4Are analysts PTs assuming BO? I’m curious how much a BP might offer knowing they’d have to pay royalties to MSK.3
u/Ramuh321Which is plenty of time to read all the DD, watch the Oct call, and come up with a reasonable guess on valuation. Not sure what your point is.1
u/SilverFoxSixNo photo?-2
u/Julbas01After thats words i'd say Sterg is in love with Sellas. I have the impression that he would like to retain Sellas and would prefer to enter into a partnership with BP. Or sell only 50%, so that he can keep Sellas as his own venture.-3
u/Remarkable-Apricot77bro is fishing for the BO-6
u/Old-Smile785They should team up with $IBRX !!-7
u/InfiniteChallenge981he is a desperate man-30
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32r/VeteransBenefitsUnconventional treatment options for knee issues. Any suggestions?jvn1983150%4261.4stem cell therapy2026-03-15
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u/Common-Jackfruit-974Bpc 157 & tb 5007
u/ski2311Curcumin Physical therapy Tai chi Ice Recumbent bike Tylenol Viscosupplementation injections5
u/manokpsaThe VA in Hawaii hooked me up with a Thermazone unit and I'm really glad they did, because I've told my primary doc, orthopedist, and podiatrist that I've seen since moving to Texas that I have one with the knee and ankle/foot pads and they all have no idea what it is. I was trying to get my primary doc to put in for the head shaped pad for my migraines and she said that isn't something the VA does (WTF? They mailed the whole thing to me on Kauai, I'm sure they can send extra parts to Texas). It's just a little machine that pumps distilled water through some tubes into the pads, and you can alternate between hot and cold. It's my favorite thing. I also highly recommend Voltaren (Diclofenac Sodium). It's a topical NSAID. I have bulging discs in my back, osteoarthritis and bone spurs in my knees, and my podiatrist just told me I can use it for my heel pain. Works well for all three. The VA first started me on it while it was still prescription-only. My mom, who worked in a pain management clinic for 8 years, begged me to share it with her. Now you can buy it at Costco.3
u/Agree_T_DisagreeI’ve tried everything as well and actually was referred for acupuncture but no one has reached out yet. For reference I had a crush injury in my left ankle and it has permanent weakness and chronic pain. Hope you get the help you need.2
u/CandidDay3337Accupuncture, physical therapy2
u/Sea_Perspective8729Ask your provider for a mri or consultant to ortho and go that route. Xrays will tell you or show you if you have arthritis or whatever else. After that get a 2nd opinion and go from there2
u/Effective-Frosting38I get steroids & anti inflammatories injected into the 3 nerves on my knee caps.2
u/ikaw-nalangI'm thinking of trying it out a year of physical therapy ( with some shockwave and aqua) and traditional Thai medicine. Bangkok hospital offers some interesting packages and is familiar with the FMP program requirements. I have tried tons of things though. Tens machine, braces, acupuncture, physical therapy helped a ton but had diminishing returns.2
u/HonestOctoWhat a great post! I had my meniscus repaired in the military. My Dad and My Gram both had knee replacements. So, it's coming for me. Thanks for sharing.2
u/Chronic_Overthink3rI have suppartz injections every 6 months. They work well.2
u/Flat-Opening1068PT helps a lot..have them put you in for it… I just had mine last week and my doctor put me in for it for my back, knee and hand.. 🫡2
u/Ok-Cheek-5487Change in your diet, I was diagnosed with celiac and found out foods can cause inflammatory issues. Cinnamon can help with inflammation which can help with the muscle tissue around your joints.2
u/Fantastic_Day3076Stem cells in Mexico1
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33r/SpinalStenosisDisc regemeration for the rich?Exact-Task-7433160%2960.5stem cell therapy2026-03-29
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u/spindlebloodGonna preface this by stating I'm no where near an "elite athlete" or have infinite money to throw at my pain. I do have DECENT health insurance (by US standards) and I've been in pain since 2022, so over time, I'm sure I've thrown a decent chunk of money at this problem (I would rather not think about how much exactly bc it's depressing.) I've tried just about everything you can possibly think of. I did contact a clinic in town here about PRP/stem cells initially for my hip labral tear which I believe contributed to my eventual back injury that occurred the same year. This clinic (Bluetail) is specifically working with the FDA to try to get insurance to start covering these procedures. And even THEY told me they would not advise getting either stem cell or PRP for my back. They indicated it might work better for my hip. Fast forward about a year after my injury, I finally saw a very well respected hip preservationist surgeon at Washington University in St. Louis about it and she basically told me not to bother with any stem cell procedures. She indicated that the "type of stem cells needed to make an actual difference would be illegal to administer in the US." I'm paraphrasing here a bit bc it's been ages since I've seen her but that's the gist. Since insurance doesn't cover it, I figured it would be a very expensive gamble. Instead of this procedure, I opted for Intracept procedure bc I was able to get my insurance company to approve it. Without insurance, it costs $45,000, roughly. It's been since January 21, 2026 that I had it. I just traveled over 4 hours on a plane last week and my back did really well, so maybe the surgery is helping me. Also a coworker of mine has had both PRP and stem cells on his bad knee and neither of them helped so he basically just lit like $14k on fire. Ugh. I've heard some ppl say they work. I'm starting to wonder if it's just a placebo effect though. I had a post surgical MRI that confirmed my BVNs were fully ablated post op from Intracept so at least I know my surgeon was effective at killing those nerves that live inside my L5-S1 bones that are responsible for carrying discogenic pain signals to the brain. Anyway I just wanted to share my perspective as someone dealing with this crap since 2022. I also worked with some of the very best PTs including Aaron Horschig (Squat University) and a guy at the Central Institute for Human Performance (McGill certified clinic.) have also communicated with Stuart McGill directly over email. I thought about saving up some money to go see him in person for an eval but I'm waiting to see if Intracept helps first. My diagnosis is DDD at L5-S1, multi level lumbar facet arthropathy, disc herniation and annular tear of L5-S1, right moderate foraminal stenosis, left mild foraminal stenosis, modic type I changes, slight retrolisthesis, and a few disc bulges at other levels that are more minor. Plus L hip tear, hip dysplasia, impingement, B/L acetabular retroversion, and persistent bone marrow edema of the right SI joint which may be nr-AxSpA.8
u/CapitalElk1169I was just approved for PRP/Stem cells here in Canada Will only cost me about $1000 CAD I looked into it in USA first and was looking at $15k USD until I found out it was available in Canada as well... Happening in a few weeks, I'll post about it after it happens and we'll see what the results are like....3
u/rvega666!remindme 1 day2
u/CoffeejiveReally wish they would write a book or just talk freely, athketes that is. If you look at Tiger, he has had 7 surgeries, says a lot re $$$ thrown at injuries. Have various tears, stenosis, impingement, oa,etc, lordosis, cervical, lumbar, knee2
u/Eastern-Sector7173Tiger woods hooked on oxys. That tells me a lot.2
u/CoffeejiveAlso, intracept, radio frequency ablation, have had x2 procedures with c being more effective than l, but the si absolutely kills pain wise1
u/Kind_Swan_7124Please look into BPC-157 and TB-500 Peptides. They will change your life.1
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34r/CerebralPalsyStem cell therapySillyPinguin50%4256.7stem cell therapy2026-03-28
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u/EffectiveFickle7451As someone with CP I honestly hate when parents are trying to “fix” their child. Kids with CP and adults can live for filling lives. Quality of life for disabled children does not mean walking or talking. It means having a safe and loving environment for them to grow and be proud of their disability in a way that they don’t believe they are a burden because of their disability. Disability is something that doesn’t need to be cured. Another quality of life is their mental health how can do things if they are depressed or have anxiety. So no i don’t think stem cell is worth it. And make sure to teach your child that their disability is nothing to be ashamed of. Honestly CP has given me a lot of opportunities. I do some public speaking for different stuff and honestly i don’t think i would be doing that or as confident if i didn’t have CP. Whether they walk or talk is something that the future holds. You should focus and building a loving relationship because people with disabilities in general are more prone to get PTSD. Thanks for coming to my ted talk!negative11
u/abayjWe are actually going to be going to Duke in the US for our second round next month. We got so many benefits from the first round. We got mood regulation [he was a very fussy baby], better eye tracking, some babbling, and arm movement. We also do a ton a therapy, so that helped too but I feel like the stem cells gave him a boost he wouldn't have otherwise gotten. Highly reccmonend an intensive therapy program after for PT and OT. Was super helpful as well. Also though, as I tell all parents, go in with the mind set it is a therapy. It isn't going to effect every child the same and you may see more or less gains then another parent. But as long as you go to a reputable clinic and it is safe, I think it is a wonderful resource!positive6
u/JAW402We are currently down in Panama getting his first treatment. He will be 2 on Saturday. We got denied for the Duke trials, and yes it's expensive. He has CP from congenital CMV, along with a couple other issues.neutral2
u/EbronsteinI live in New Jersey and I'm trying to get any info I can on stem cells. Does anyone know anything? ?neutral1
u/WatercressVivid6919Have you tried posting this in the Discord server? https://discord.gg/tEuptRdKDz ?neutral1
u/bob-the-liciousAnd since we are all here - any recommendations around PHX for stem cell practitioners? We have our stem cells banked for the kiddo but our doc retired. We have a ton of therapy in PHX in July and would avoid flying around (coming from Belgium and all). ?neutral1
u/Dark_Rottie18I tried to apply quite a few years ago but at the time they were only taking children, not adults. Which makes sense, but still.....😡😡negative1
u/curious-dev199Can someone please share some light on the cost it takes for someone who is not in the US for this treatment? Also what's the max age this treatment is done? Thanks in advance! ?neutral1
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35r/SecretsOfMormonWivesWhat do the girls want from Demi?Positive-Canary93471170%5756.4stem cell therapy2026-03-13
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u/jake3h7mI’m so glad you said this! I was so confused at their reaction to her not hanging out with them before DWTS as well. Whether it’s to her face or behind their back, they make it very clear that they do not consider her their friend or that she ever will be again. But then they got upset that she was staying at a separate hotel and was just meeting up with them for DWTS? What other obligation does she have other than that event? Why do they make it seem like it’s so terrible that she doesn’t want to hang out with them beforehand or stay at the same place when they make it clear that they collectively hate her?103
u/Fear_PearI personally want a full cover of "True Colors" because that was the funniest thing I've ever seen57
u/Own-Ad-7201They want her to be the polarizing villain because without her the attention goes back to showcasing their own problematic behavior. It was comical when Taylor was like her absence puts so much pressure on us and we have to scramble. There’s like 7 of them, how is her absence making that much of a difference for yall.50
u/jake3h7mThat part! plus Whitney is the only one whose consistently been spot on when it comes to shit like this even when her opinion may not be popular she’s usually been proven right and I just think it’s very telling that despite how much she loves momtok now and is in the show she still supports Demi and I dont think she would still bring it up or be by her side unless she felt she had a reason, especially with how important her career is to her. idk.47
u/bephanaThey wanted to bully her again, at this point they just always need a person present that they can shit talk to.44
u/SupportPretty7228But they don't care what Taylor does? Taylor can flirt with Chase and it's no big deal? How the girls choose who to hate on for what makes no sense. They have the maturity of middle schoolers24
u/SarppaliTHIS!!!! Like it makes no sense. It is all just for clout to make it more interesting. Like I would NEVER go back to people like that, the way they treated her even if its somewhat justified.23
u/karenscafeI was thinking the same thing. I couldn’t understand why they were so pissed she wasn’t around when they made it clear they didn’t want her there? It’s weird. They should’ve been happy she wasn’t showing up and quit filming. But they’re not because they realize this is a TV and they need a villain. Which makes all their talk about who’s “genuine” sound ridiculous.23
u/GaladrielllllOkay sorry this message is long: Okay, I obviously don’t know any of these people personally — I only know what’s shown on the show, social media, and what’s discussed online. I do have a Master’s in Psychology (I’m not a practicing therapist, and I finished the degree within the last couple years), so take this purely as an observation from someone who studies behavior — not as a professional diagnosis or anything like that. Honestly, the biggest factor that people often forget with reality TV is production. Producers shape storylines every season because conflict keeps viewers engaged. Editing, selective clips, and encouraging certain conversations can amplify issues that might otherwise be small or resolved quickly in real life. So when something feels confusing or inconsistent to viewers, a lot of the time it’s because we’re seeing a highly curated narrative, not the full context of what actually happened. From a behavioral standpoint though, I can see why tensions around Demi keep resurfacing. On the show, she sometimes communicates in ways that come across as blunt, confrontational, or dismissive toward the other women. Whether that’s editing or her actual communication style, that kind of delivery can trigger strong reactions in group dynamics — especially in tight social groups where loyalty and perceived respect matter a lot. Group psychology also plays a role here. Once a group forms a shared perception about someone (fair or unfair), it tends to reinforce itself. People start interpreting that person’s actions through the lens of “this is who she is”, even when the behavior might be neutral or unrelated. That can create a situation where the person is “damned if they do, damned if they don’t.” If Demi shows up, people may interpret it as performative; if she doesn’t show up, it’s taken as proof she doesn’t care. Another thing that often happens in reality TV groups is what psychologists call social contagion or group polarization. When several people share frustrations with one person, those feelings can intensify over time as the group validates each other’s perspective. What might start as a disagreement between two people can quickly become a larger group conflict. That’s why the reactions you’re describing can look contradictory: • They say they don’t trust her or want distance, • but then they’re upset when she actually creates distance. Psychologically, that tension often comes from unresolved conflict. People may say they’re done with someone, but emotionally they’re still reacting to the situation. And then you add the pressure of filming, public scrutiny, social media commentary, brand obligations, and producers pushing for conversations — and it becomes a perfect storm where conflicts keep getting revisited. So from my perspective as someone who studies psychology (again, not diagnosing anyone): it’s probably a combination of reality TV production, group dynamics, communication style differences, and unresolved conflict. When all of those things collide on camera, it can make everyone’s reactions seem confusing or hypocritical from the outside. That’s just my take watching as a viewer though — the reality is we’re all seeing a very edited version of a much bigger story.21
u/Sea_Papaya_419They all, including Demi did the same thing to Whitney. They don’t think you should come and go into mom tok/ decide when you’re going to be friends with the girls whenever you want something. I also think a lot of it is edited especially the confessionals because they all follow Demi except Jen on socials so🤷‍♀️19
u/Greedy_Bit8650Their tryna bring her back for a storyline  tbh the whole Marciano thing would work if they didn’t broadcast and try to create a storyline with the sa accusations, they wouldn’t have much of an controversy bringing her back14
u/LittleBabyOprahI was hoping to tune in this season and finally see the problematic ass storyline left behind but no, Hulu just haddddd to revamp this beef that no one cares about except Jessi because it distracts from her own actions and her weird sad marriage, and Jen because she has the maturity of a zygote. Calling Demi on speakerphone gave me middle school flashbacks, that was so cringe.11
u/haleykatThey want her to be the villain so they can be catty and not get any hate.10
u/Inevitable-Past-4069These women equate showing up for any and all events to how much worth they think someone has as a friend, but only selectively. They barely shit on Jen for not making maycis book launch because she was sick (not because she was, you know, busy rehearsing for DWTS 6-8 hours a day everyday) but they DRAGGED Whitney for not coming when she was doing the same thing as Jen??? Also Taylor has missed plenty of events but I never hear them shitting on her, she's always excused for her absences and her atrocious behavior...8
u/shay_shawI’m watching the episode with the reunion and it’s even more clear that Jen fucking lied about what she saw. And Jesse is out of her mind for being so judgmental when she was the one who actually cheated on her terrible husband. I don’t think she went hard enough on Jen, I would’ve lost my mind. That kind of betrayal on national television, I would’ve hit below to belt too.7
u/libreotusi am sure a lot of it has to do with them feeling like it isn't fair that she is being paid under contract when she isn't "working". i'm sure they're all tired of the cameras 24/7. i know the moms on dance moms would get pissed at melissa for not "doing her job" and participating in the drama the producers were orchestrating. the show makes them all look bad and they probably think that if they have to keep showing their asses on TV then demi does too if she wants the benefits. though really they should consider how hated demi is even without the screentime lollll they really don't need to go so hard on her at this point. i'm not a demi fan but good lord some of the scenes were intense6
u/whydoyou_caresomuchI think a lot of the issue is all the shit Demi was posting online during this time. The comment sections too. That’s what is hard about the show coming out later on. I was legit so confused when it started out with them all being cool. In my mind filming started after the Reunion, but as we know, it didn’t. Hahah6
u/Rosemary-Sea-SaltProbably to disappear but the producers said 🙅‍♀️3
u/bigtimechipDemi is the biggest cry bully ever and was piggy backing off of Macy and Mikayla's abuse situations to garner sympathy for herself. Low key disgutsing behaviour2
u/Hollinsgirl07I think it’s the hypocrisy of it all. She chose not to go to Whitney’s event for mental health but couldn’t accept that from anyone else as a valid excuse. She got upset after the reunion and “quit” but still wants to go to on camera events with the girls. I think they feel like if she wants to leave she should fully leave or fully stay. Which I get. Like pick one and really show up or don’t ever be on the show again. If she wants to stay for the clout fine but like own up to that and move on.2
u/CaterpillarNearby422They all need therapy lol1
u/KLC_BIt really feels like Demi is in an abusive scenario. If she’s saying different things in private I feel she just doesn’t want anything on camera than the story she may have fabricated to her geriatric husband1
u/lquintelI thought they were mad she went to DWTS? Why would she go and sit with them and play nice for the cameras when they aren't speaking? Doesn't make sense. Thats how I took it anyways, that they didn't want her there at all1
u/snipsnap987what demi said in the reunion crossed so many lines, and to girls that are less confrontational or good at confrontation (miranda, mayci, and jen). i really don’t think demi should come back to the show after that, and i think the girls are annoyed demi is pretending to be part of the group but doesn’t show up. and in a way that’s hypocritical since demi has bullied the other girls (whitney, taylor, and jen) when they didn’t show up to film for mental health reasons
u/Few_Essay_5197they want accountability and for to just own up to her BS. also this a scripted reality show as well as they are influencers who get views for drama. I don't think they don't want to be her friend, they just want her to be a better her.-2
u/OppositeSpare2088Demi is still a snake I wouldn’t trust her or Whitney actually I wouldn’t trust anyone on this show lmao. I think Demi doesn’t want to be seen as the villain anymore and wants to get on everyone’s good side again. Imo she’s also doing it to try to get more people to side with her with the Marciano situation.-3
u/CreepyRelation968They don't want anything from Demi, that's the point. No one wants to be around Demi so they are rationalizing their thoughts by discussing it.-4
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36r/KneeInjuriesGrade IV chrondromalacia patella. HELP.Tight_Imagination19440%3354.9stem cell therapy2026-03-18
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u/fireflysucks1Hi CMP Grade 4 here.. Took PRP Injection , i am too 33, doctor said this is the right age to took the injection. At first it was a relief but after a month or two the pain came back.5
u/RacacooonieConsider yourself lucky if not in pain. My chronic pain for five years led me to do MACI/TTO. I’d tried all conservative treatments and even surgery prior. This is helping, though, thankfully! Do you have a really great PT? I had to go private pay to get one that actually knows what she is talking about and has helped me in conjunction with my surgeon. There is hope. Keep working on it and advocating for yourself.3
u/idkman1768I had severe chondromalacia patella and had partial knee replacements in both knees3
u/StrictOrganization76Hola yo soy de España 50 años estoy con condromalacia rotuliana grado 4 con hueso expuesto y rótula alta ya an probado con una infiltracion de ácido hialuronico y dos de prp y sigo con más dolor después de todo, en junio me dicen cual es el próximo paso, alguien que aya pasado por lo mismo, muchas gracias por todo y fuerza a todos3
u/milobindiMight be a good candidate for MACI surgery if it is causing you pain in day to day activities. You could ask your ortho.2
u/Immediate-Lecture-20hi i have had grade 3 in one and grade 2 in another knee ans same age as you..my pain was healed with good consistent pt and then i later joined gym to strengthen my thigh muscles and stuff! That has made a lot of difference for me! I am not a fit person. so it still does pain every now and then if I push myself a bit. but it has improved for me. It took almost an year for me. let me know if any other questions2
u/jumaamubarakbitchesBe thankful it’s lateral and not medial. I’m 5 weeks into microfracture surgery with autocart on medial femoral condyle and I should be partial weight bearing by the end of next week despite my knee currently at 83 degrees. It’s not fun! At least lateral is not the weight bearing part of the knee. Silver lining.2
u/Sea_Perspective8729With this condition PT helps for the time being i dealt with these symptoms in my early 20s and yea I felt pain walking up stairs but just dealt with it.In my late 40s I ended up tearing my meniscus on the medial and lateral side of my right knee due to degenerative changes within my knee.Eventually I had my left knee replaced as I had grade IV chondro.So yea get a 2nd opinion and go from there. Good luck.2
u/HauntingAd1585Next step is going to be surgery. Theres no reversing it unfortunately1
u/StrictOrganization76From what I see, everyone with this type of injury ends up with a knee replacement; I have an appointment with my orthopedist in June.1
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37r/InterstellarKineticsA 21-Year-Old New Yorker Became The First In The State Cured Of Sickle Cell Anem...InterstellarKinetics470%154.2stem cell therapy2026-04-03
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u/InterstellarKineticsThis is not the absolute first sickle cell cure. FDA-approved gene therapies have succeeded since late 2023, but it is New York’s first, and Beauzile’s symptom-free status after 21 years underscores the therapy’s impact. The real bottleneck now is not efficacy, but the $3 million price tag and manufacturing capacity. Bone marrow transplants were the prior “cure,” but donor scarcity limited them to Approximately 20% of patients. Lyfgenia uses the patient’s own cells, solving that entirely.3
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38r/physicaltherapyIs trying shockwave / hyperbaric / stem cell stuff actually worth it?Glittering_Seesaw_3250%1553.3stem cell therapy2026-03-22
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u/MindlessPromise5164nah save your money 💀11
u/sapionaturalI don't think there's any danger in trying shockwave, especially since the classic approach didn't work for you. No guarantee it'll work, but it may help restarting the healing process and increase your pain tolerance. Sure many physios here will disagree because of all the passive (and sometimes manual) modalities hate8
u/CommercialAnything30Hyperbaric is over rated unless your job relies on your Achilles. I researched this for someone not long ago and it requires 90 minutes a day for 12 weeks to get the benefit. Beyond that, no one knows the minimum requirement for maintenance beyond that initial protocol. Shockwave is worth it imo since you have tried everything else. Shockwave plus exercises.5
u/DrgnFly5[deleted]4
u/Ezdoesit1Anecdotal but I like shockwave for stubborn tendinopathies that are more chronic4
u/SentientScarecrowThere is some good research for it and it can't hurt to try if you have the money. I would also recommend you look into percutaneous needle tenotomy. If there's a provider in your area who offers it, I would recommend consulting with them. We see good results in treatment-resistant Achilles issues. ETA it's typically done by Ortho MDs4
u/OddScarcity9455No3
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u/halfserious3two years in with solid pt means the fundamentals are there. shockwave has legit research but the real issue is usually how people ramp back up, not the tissue itself. most get the same result from being way more conservative with the progression and that's free.2
u/VO2VCO2Since it's lasted so long I would try combining few Shockwave treatments with heavy resistance exercise. Did you actually go hard with the exercises for an extended period of time? Skip on the other two. Placebo effect at best but small chance of serious consequenses = skip.2
u/Living-Protection250I think most people I’ve seen in that situation end up realizing it’s less about finding the “next thing” and more about how well the loading and progression actually sticks long term. Some of those options do get used, but from conversations I’ve had, they seem to work best as an adjunct, not a replacement for a solid, consistent loading plan. Otherwise it’s easy to get temporary relief without real carryover. You’re definitely not overthinking it though, chronic tendinopathy can be frustratingly slow and non-linear. Curious what others here have actually seen move the needle in these stubborn cases.1
u/1giftedangelShockwave has produced results in myself and others.1
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39r/diabetes_t1Question for people living in countries with free healthcaren - do you think ste...Virtual-Medium-589140%1251.6stem cell therapy2026-04-01
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u/ben_jamin_hStem cell therapy would become free in countries with healthcare when the cost of the treatment becomes equal to or less than the cost of insulin treatment, or when the people in charge of the healthcare budget decide that the benefits are worth the cost. They would probably prioritise children and pregnant women at first, and then younger adults, and then middle aged adults, and then older adults, as the young would live a longer life without relying on insulin therapy... So whenever it does happen I'll be way down the list 😂 If stem cell therapy is scaled and prices go down, it might be possible one day. It would all depend on the cost.10
u/amanset[deleted]5
u/anti-sugar_dependantDepends on how well it works I think. The NHS, well NICE, requires evidence that a new treatment is worth the cost. So the reason all T1Ds now automatically qualify for a CGM in England is that NICE looked at the evidence and decided that it's cost effective to give all T1Ds a CGM because it enables better control, which reduces complications, which cost a lot of money. Basically the same reasoning for why we get free prescriptions. So if stem cell treatment works out cheaper than treatment with a hybrid closed loop, taking into account all the long term effects, that's probably what they'll do. And if it's not cheaper they'll probably stick with HCLs.3
u/DamnknitI don’t think it would be free. Maybe eventually but definitely not at first. We don’t have to pay to go to the doctor or hospital but we still have to pay for all prescriptions including insulin and CGMs. There’s government programs that can help but don’t cover the whole cost. It’s significantly less than somewhere like the US but some medications are still very expensive unless2
u/YlsaniLikely yes but probably 10-15 years if not more after it's approved.1
u/Chance-Ask7675Of course. It will follow the same trajectory as every other drug or treatment that comes to market. And that very rarely includes an expectation to pay out of pocket in places with socialized healthcare. First it will be experimental, then covered for priority groups, then more widely available. Drug companies price drugs with this in mind and negotiate with healthcare authorities, they dont just set the price at a million dollars and say "too bad, you dont pay no one gets access" lol. They'd never get anywhere if it was only available to rich people willing to pay out of pocket and doctors wont waste their time learning the necessary protocols if thats their patient pool.1
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40r/ParkinsonsTV Report on Kenai's Stem Cell Trial in LAIll-Lavishness4274140%251.2stem cell therapy2026-03-27
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u/OneWingedJokerLove your posts. Particularly as an EOPD lottery winner, keeping a hopeful eye on the future definitely helps. Thanks for these updates!3
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41r/covidlonghaulersThrone Biotechnologies stem-cell educator therapy for LCsaintmars77780%451.0stem cell therapy2026-03-06
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u/Many-Market-9941This is the kind of conversations we should be having on this sub! We have spent enough years speaking about supplements, mind body work, or even medications like LDN, which can provide relief to some but are not the solution we need to ‘nuke’ this syndrome for once and for all2
u/berryenthusiastI'm in the process of sending them my information. They're done with trials it's now considered treatment. I was hyped about it until they sent me this: "Payment in full for treatment is due before or upon your arrival the day prior to your first scheduled treatment. At this time, the charge for the first treatment is $39,000. If you elect for the follow-up treatment 8-14 days after the first treatment, the charge for that is an additional $10,000. Payment should be made by wire transfer. Wire transfer instructions will be provided" https://patients.thronebio.com/further-details-of-thrones-stem-cell-treatment-for-autoimmunity/ I also can't find any testimonials. So. I'm a bit disappointed.2
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42r/KoreaSeoulBeautyHas anyone tried stem cell skin treatments in Seoul?Lonely-Jackfruit-54620%1048.0stem cell therapy2026-03-09
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u/External_Cost1541I did the stem cell recently, there are like many different types of stem cells that you have to choose one of them as it all has a different purposes u know, for 7 days couldnt drink, smoking, or do saunas but yeah I think it was worth it oh and one important thing that I heard with the stem cell thing it is a recent treatments so you have to go to the clinics where it is gov certified1
u/Icy_Working_3732I actually tried a regenerative skin booster when I was in Seoul last year. From what the dermatologist explained, a lot of what clinics call “stem cell” treatments are more like growth factor or regenerative boosters rather than literal stem cells. It helped my skin look smoother and more hydrated after a few weeks, but it wasn’t like an instant dramatic change. The improvement was more in texture and glow.1
u/Apprehensive-Car3588I did a stem cell/rejuvenation at Wooa dermatology and you probably already know it was more of an anti aging treatment using your own blood and then they followed it with Vitaran/PDRN injections and finished with LDM treatment as part of the package. I wouldn’t say it gave me some crazy overnight transformation but my skin did look a bit healthier and more refreshed afterward1
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43r/diabetes_t1NewcelX and Eledon partner up for a new stem-cell + immune modulation therapyDavidAGMM100%147.5stem cell therapy2026-03-15
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u/_ducttape_I don't know why this news is not getting more press - maybe it is just early? The news right now is around the islet act passing - but if this would be islet cadaver transplants, which are not the path forward for large scale. Or maybe that is for the next 5-8 years and in 8-15 years it goes with these type of cells? <insert joke about 5 years here>1
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44r/AgingDoes stem cell therapy increase you lifespan?SpecialK23520%847.3stem cell therapy2026-03-21
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u/thelostdutchman68Local therapeutic stem cell injection does not have an effect on lifespan. Injected stem cells are not integrating into you systemic stem cell pool or depleting it. They act locally and transiently.3
u/peglyhubbaWow that is great to know. I’ve had my own stem cells put into my knees. And my own protein rich platelets also injected intro my non existent cartilage. My knees are so happy. They will live on without me! Haha 😂2
u/pandit_the_banditI have had almost $100,000 of treatment from Regenexx in Cayman Islands and there is ZERO chance it will extend my life. It’s solely to treat orthopedic problems2
u/WanderirGenetics is first when it comes to longevity, them environment and lifestyle they follow by a wide margin. I’ve not seen or heard of any evidence for stem cells. Do a search for studies.2
u/raj_uvGenetics and lifestyle balance is key. Stem cells only increases chances of positive outcomes as everything is subjective to the individual case at hand. I get stem cell IVs and enough exosomes for anti aging twice a year in Switzerland but I’m overall healthy and no underlying issues or injuries. In your friends case if she is getting localized injections that’s not enough for longevity imo maybe good enough from injury to recovery and some added benefits but if she’s getting IVs with enough stem cells and exosomes or growth factors then she has increased odds but no guarantees2
u/iNap2MuchCan't speak for stem cell therapy, BUT... stem cell TRANSPLANT can save your life. If you need one.2
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45r/backpainExploring stem cell research for back painQuick_Rutabaga_935630%446.8stem cell therapy2026-03-14
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u/Waste_Opening_9920It’s definitely an interesting area of research. Mesenchymal stem cells from sources like Wharton’s Jelly are getting a lot of attention in regenerative medicine especially for things like joint and back issues. I think sharing educational info helps people understand the science better before making any decisions. For anyone curious about the topic, looking into resources from projects like Stem Cell Club can be a good starting point to learn more about the research and how these therapies are being explored.1
u/ReplacementLevel8619You're better adressing It with whats avaliable already, stem celss themselves wouldnt work without adressing aspects of spine and Disc degeneration1
u/AutoModeratorPlease check out the r/backpain wiki for some first steps for new low back pain & FAQs [ https://www.reddit.com/r/backpain/wiki/index/ ] PLEASE NOTE: When Asking for help it is up to you to recognize when to seek medical attention. Anyone giving advice in this group is doing so from anecdotes and holds no liability. Seek advice here at your own risk. Remember to be kind & respectful. There is always a way We are rooting for your success Posts and replies that do NOT show kindness and empathy towards others will be deleted. I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.1
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46r/backpainExploring Stem Cell Approaches for Chronic Back Pain – Evidence and Clinical Per...Quick_Rutabaga_935630%446.8stem cell therapy2026-03-13
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u/AutoModeratorPlease check out the r/backpain wiki for some first steps for new low back pain & FAQs [ https://www.reddit.com/r/backpain/wiki/index/ ] PLEASE NOTE: When Asking for help it is up to you to recognize when to seek medical attention. Anyone giving advice in this group is doing so from anecdotes and holds no liability. Seek advice here at your own risk. Remember to be kind & respectful. There is always a way We are rooting for your success Posts and replies that do NOT show kindness and empathy towards others will be deleted. I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.1
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47r/kidneydiseasemesenchymal stem cell infusion therapyFan_Fav10%1245.6stem cell therapy2026-03-11
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u/Select_Safe548Sounds new or experimental. What country are you in?2
u/TheAbominableAlfieI'd be hesistant to pay that without extensive research and guarantees. Dialysis is over 50k per year. If this treatment worked it would be a lot more than 27k. It looks like they've developed a price point which some people would be willing to gamble on.2
u/Here-2-Help2622Muse stem cells for 10k at DBC1
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48r/Science_IndiaJapan Approves Stem-Cell Treatment For Parkinson's In World FirstVCardBGone50%44.5stem cell therapy2026-03-06
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49r/AskTurkeyVisiting Edirne in April. I need information about TRAKYA UNIVERSITY HOSPITAL fo...ChangingSong10%743.8stem cell therapy2026-03-22
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u/GaelenmyrDo public hospitals even offer advanced treatments to foreigners? I thought they were for citizens and residents only. Foreigners (non-residents) usually go to private hospitals.4
u/ChangingSongOh my goodness! I truly appreciate your concern and your reply. I can tell that you only want to help me and I think you are very kind to care.1
u/danceofeternity_0Hi I am from Edirne. Actually u can contact secretary of hospital. I suggest that take appointment from directly to prof doc. I don't know if they ate doing stem cell therapy btw.1
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50r/InterstellarKineticsBREAKING: A One-Time CRISPR Gene-Editing Therapy Just Eliminated Painful Sickle ...InterstellarKinetics40%143.5stem cell therapy2026-04-02
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u/InterstellarKineticsThe 27 out of 28 number is the one that will anchor this story in the literature. Clinical trials for severe genetic diseases rarely produce outcome data this clean. The one non-responder in the cohort will be studied as carefully as the 27 successes because understanding what made that patient’s biology different is the key to predicting which future patients will respond. The donor registry disparity angle also deserves more attention than it typically receives in CRISPR coverage: bone marrow transplant as a cure for sickle cell disease has existed for decades but has functioned, in practice, as a cure primarily available to patients with a matched sibling donor, which skews heavily toward smaller families of European ancestry. An autologous therapy that requires no donor erases that disparity by design. If reni-cel moves through regulatory review with this data supporting it, the access question shifts from biology to economics, and that is a different and more solvable problem.1
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51r/SicklecellAbout 1% of eligible sickle cell patients have received gene therapy since appro...tucksedo40%43.5stem cell therapy2026-03-19
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52r/ScienceNcoolThingsA new stem cell therapy helped grow stronger bones in people with osteoporosis, ...sibun_rath1090%42.9stem cell therapy2026-03-25
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53r/stemcellsIs stem cell therapy for autism abroad even worth considering?hot55x20%242.8stem cell therapy2026-04-01
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u/hostofthetabernacleAre you aware of the GAPS diet for autism? We put our son on it and the changes were pretty noticeable. The nice thing is that it is cheap and risk free. The challenge is finding stuff that they are willing to eat especially after they are accustomed to the standard diet. Luckily Ai has been pretty helpful in this regard. That said I would recommend MUSE cells which are a type of stem cell that can cross the blood brain barrier. Our son has cerebral palsy and autism and the stem cells have definitely made a difference. Just beware of any clinic that claims that one treatment will be enough and make sure they are used to dealing with pediatric patients. Feel free to dm me for clinic recommendations we did a crazy amount of research before deciding on a clinic that we felt like we could trust.1
u/Ryan_MedConsultantIt totally makes sense you’re looking into this, but the hard part about the "abroad" search is separating the actual medical protocol from the clinic's marketing. The fastest way to make this less overwhelming is to pin down one missing piece. Instead of focusing on the destination or how fancy the hospital looks, it usually helps to narrow down the exact cell source and administration route (like IV vs intrathecal) first. When you were looking at those clinics, did they actually explain why they use a specific route for a 6-year-old, or was it left pretty open-ended?1
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54r/phlebotomyWhat type of phlebotomy am I doing at a stem cell therapy clinic?alyssapere20%242.8stem cell therapy2026-03-25
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u/Constant-Quality-692You'd be the phlebotomist at that office,  but still performing regular lab testing just like at any other lab, hospital or office. It's not donor phlebotomy, it's just at an specialty office but same as "regular" phlebotomy,  so not considered a step up exactly. Except that most people really enjoy working as a phlebotomist for a single medical office.  But congratulations! I work at a specialist office as well and absolutely love my job.1
u/Ambitious-Candy-4190You probably won’t actually be collecting the stem cells, I would think it would be like any other clinic and you’ll still just be getting routine draws or maybe some specialty tests1
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55r/ibsStem Cell Therapy for IBSusername63842910%542.7stem cell therapy2026-03-22
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u/goldstandardalmondsIt’s only in clinical trial stages and experimental. You’d have to join a clinical trial.1
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56r/BANDOFBROTHERSOFSRNEWith FDA go ahead, a China biotech notches a first in cell therapy testing - Hop...Leather_Landscape_20190%42.3stem cell therapy2026-03-14
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57r/kbeautyHas anyone tried stem cell skin treatments in Seoul?Lonely-Jackfruit-54630%42.3stem cell therapy2026-03-09
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58r/StemCellsForumWhat are your thoughts on stem cell therapy for chronic diseases?Quick_Rutabaga_935620%140.5stem cell therapy2026-03-20
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u/GordianNaughtIt won't be mainstream in the United States any time soon. In other countries the treatments are widely accepted1
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59r/backpainCan stem cell therapy actually heal injuries instead of just hiding the pain?Quick_Rutabaga_935620%140.5stem cell therapy2026-03-15
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u/AutoModeratorPlease check out the r/backpain wiki for some first steps for new low back pain & FAQs [ https://www.reddit.com/r/backpain/wiki/index/ ] PLEASE NOTE: When Asking for help it is up to you to recognize when to seek medical attention. Anyone giving advice in this group is doing so from anecdotes and holds no liability. Seek advice here at your own risk. Remember to be kind & respectful. There is always a way We are rooting for your success Posts and replies that do NOT show kindness and empathy towards others will be deleted. I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.1
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60r/IHaveParkinsonsStem cell transplants are sounding like the best prospect yet. I’d love to see t...dannieandme20%40.5stem cell therapy2026-03-20
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61r/TheCreativeContentTop Benefits of Adult Stem Cell Therapy in Chicago for Joint Painerepresent20%40.5stem cell therapy2026-03-14
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62r/Science_IndiaStem Cell Therapy Enables Two Women With Asherman's Syndrome To Become MothersVCardBGone20%40.5stem cell therapy2026-03-12
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63r/stemcellsISO Stem Cells. NYStill-Arugula577310%239.8stem cell therapy2026-03-18
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u/Primary-Ruin8830I was involved in a study here in Houston For my TBI, where they injected, stem cells from my own adipose tissue via IV. I think it has helped me out 10 to 15% I am Looking into more stem cell treatment. Let me know what you find.1
u/Still-Arugula5773I heard Dr. Calapai in Garden City NY is the go-to for stem cells, alternative and regenerative medicines. Will have to check him out.1
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64r/OrthopedicsChronic reactive synovitis after meniscus surgery – stem cells or partial synove...Queasy_Pea493010%137.5stem cell therapy2026-03-29
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u/SeL-MoGRCForget stem cells, as helpful as placebo. Do you have underlying connective tissue disease? 'Chronic reactive inflammatory synovitis' is a throwaway term used by the unskilled to explain a patients poor outcome. Synovectomy has limited indications. Age, sex, occupation, BMI, xrays would help me give you a better explanation.1
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65r/WealthyPFSaw Reddit post on stem cell travel vs local care—hope meets budgetjaredscrawford10%37.5stem cell therapy2026-03-24
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66r/BiohackersAnonymous Stem Cell SurveyDifferent_Cancel_62610%137.5stem cell therapy2026-03-10
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u/AutoModeratorWelcome to r/Biohackers! A few quick reminders: - Be Respectful: We're here to learn and support each other. Friendly disagreement is welcome, but keep it civil. - Review Our Rules: Please make sure your posts/comments follow our guidelines. - You Get What You Give: The more effort and detail you put into your contributions, the better the responses you’ll get. - Group Experts: If you have an educational degree in a relevant field then DM mod team for verification & flair! - Connect with others: Telegram, Discord, Forums, Onboarding Form I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.
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67r/PrefectContentThe Future of Pain Treatment: Stem Cell Therapy Clinics in Chicagoerepresent10%37.5stem cell therapy2026-03-14
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68r/TheWideContentIs Stem Cell Therapy in Chicago Right for You? Everything You Need to Knowerepresent10%37.5stem cell therapy2026-03-14
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69r/PrefectContentStem Cell Therapy Chicago: Can It Help You Avoid Surgery?erepresent10%37.5stem cell therapy2026-03-14
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70r/TheWideContentStem Cell Therapy Chicago: Benefits, Process, and What to Expect from Adult Stem...erepresent10%37.5stem cell therapy2026-03-14
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71r/TheCreativeContentHow Stem Cell Therapy in Chicago Is Transforming Regenerative Medicineerepresent10%37.5stem cell therapy2026-03-14
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72r/PrefectContentStem Cell Therapy Chicago: A Non-Surgical Option for Joint and Tissue Repairerepresent10%37.5stem cell therapy2026-03-14
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73r/TheWideContentWhy More Patients in Chicago Are Choosing Stem Cell Therapy for Pain Relieferepresent10%37.5stem cell therapy2026-03-14
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74r/TheCreativeContentStem Cell Therapy in Chicago: A Modern Solution for Chronic Pain and Joint Injur...erepresent10%37.5stem cell therapy2026-03-14
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75r/PrefectContentAdult Stem Cell Therapy in Chicago: How Regenerative Medicine Can Help Heal Join...erepresent10%37.5stem cell therapy2026-03-14
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76r/NoFilterNews/r/worldnews - https://realmwire.com/japan-approves-two-groundbreaking-stem-cell...Faction_Chief10%37.5stem cell therapy2026-03-06
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77r/AskDoctorSmeeeeAnonymous Stem Cell SurveyDifferent_Cancel_62610%37.5stem cell therapy2026-03-05
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78r/tryingtoconceiveIs stem cell therapy for autism even worth looking into?lunefaeryy0%137.5stem cell therapy2026-03-30
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u/AutoModeratorHi! Welcome to r/tryingtoconceive! Please be sure that you have read our rules before posting or commenting in this sub. Multiple rule breaks may result in a ban from this community. Please note: Discussion of current pregnancy, pregnancy announcements, and photos of HPT’s are not allowed outside of the designated thread. (“Weekly BFP/Line Eyes Post”). Don't see your post? Our automod filters posts due to keywords, images, and low post or comment karma. If your post is not showing up right away, it is likely awaiting moderator approval. Please be patient as we are not always online but will have your post approved or removed ASAP. We typically let you know why a post was removed. You may find our PSA post regarding the luteal phase helpful if you find yourself symptom spotting and wondering what is going on. We also have a designated thread dedicated to discussing OPK's, general topics like the TWW (two week wait) that is pinned. New to OPKs? You may find our PSA post regarding OPKs/Ovulation Tests helpful if you are unsure if your test is positive or have questions about taking them. Please report any rule breaking. If you are unsure if it breaks the rules, report it and mods will review it or reach out to the moderators via Modmail. Remember to keep discussions civil. I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.
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79r/newjerseyExploring Regenerative Medicine Options in NJ: Stem Cells, Exosomes, and Peptide...DecentDamage29200%37.5stem cell therapy2026-03-19
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80r/stemcellsAnonymous Stem Cell SurveyDifferent_Cancel_62610%137.4stem cell therapy2026-03-03
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u/Thoreau80How does it help?1
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81r/stemcellsStem Cells for Fetusesswarrenlawrence10%37.4stem cell therapy2026-03-03
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82r/upliftingtrendsJapan gives green light to first-of-their-kind stem cell therapieshata3970%31.0stem cell therapy2026-03-18
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83r/stemcellsWhat is your take on stem cell therapy for dementia?Obvious-SnowyDust20%430.0stem cell therapy2026-03-24
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u/GordianNaughtTBI yes....dementia no.3
u/DeyabMDDementia is a symptom that may be from several very different diseases that one solution (stem cell) won't be the answer for them all3
u/mother_jeongyeonIt works but you need specialized neurological stem cells for that, mesenchymal won’t do anything1
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84r/stemcellsDoes anyone know of anywhere in Illinois that provides stem cell therapy? I have...ethankrafft10%224.8stem cell therapy2026-03-30
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u/Tight_Stable_9355https://duckduckgo.com/?q=reputable+stem+cell+therapy+in+illinois&ia=web1
u/FaithlessnessOdd1346You can send me a PM and I can get you in a call with a provider in your area1
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85r/RegenerateEverythingStem Cell Therapy Offers New Hope for Joint and Ligament InjuriesMargotli10%22.5stem cell therapy2026-03-27
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86r/RehealthMexico vs USA stem cell therapy – is it really worth traveling?Equal-Procedure585110%22.5stem cell therapy2026-03-20
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87r/udemyfreebiesStem Cell & Gene Therapy Online Coursesmartybrome10%22.5stem cell therapy2026-03-13
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88r/INErectileDysfunctionThank you STEM CELL THERAPY for fixing my Erectile Dysfunction Permanently. If y...ED_Healer10%22.5stem cell therapy2026-03-11
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89r/u/Calm-Blueberry-9835✨️China reports experimental stem-cell therapy restoring insulin production in s...Calm-Blueberry-983510%22.5stem cell therapy2026-03-04
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90r/ScienceFeed[News] - Stem cell therapies ‘come of age’ with two conditional approvals in Jap...eventdawdling10%22.4stem cell therapy2026-03-03